Sentences with phrase «as osteoblasts»

Cells known as osteoblasts make new bone; other cells, osteoclasts, destroy old bone.

Not exact matches

Once there, the protein acts on the osteoblasts and inhibits Wnt activity, which is a cellular signalling pathway that is involved in the formation of the skeleton and in certain disorders, such as osteoporosis, arthritis and myeloma.

The parasites might trigger these problems, the scientists hypothesized, by upsetting the normal balance between cells known as osteoclasts, which dissolve bone, and cells called osteoblasts, which build it back up.

To find out, Deb and his co-authors genetically tagged cardiac fibroblasts in mice and watched as they transitioned into bone - forming, osteoblast - like cells after heart injury.

Furthermore, since the cells responsible for synthesising new bone tissue (osteoblasts) are known to attach close to the tip, it would appear that the electric field distribution signals this point as the centre of damage, becoming a moving beacon for repair efforts as the crack is healed.

These products, including the major malarial by - product hemozoin, malarial proteins and as yet undefined virulence factors, induce MyD88 - dependent inflammatory responses in osteoclast and osteoblast precursors, leading to increased RANKL expression (a key molecule inducing osteoclast differentiation), and over-stimulation of osteoclastogenesis favoring bone resorption.»

Our bones are in a constant state of flux as the number of bone - making (osteoblast) cells fluctuates, while the number of bone - degrading (osteoclast) cells also adjusts.

Mesenchymal stem cells express a surface protein called α4β1 integrin as they turn into osteoblasts.

Mineralized human primary osteoblast matrices as a model system to analyse interactions of prostate cancer cells with the bone microenvironment.

Human primary osteoblasts matrices as a model system for bone metastasis research.

In addition to iPS cells derived from progeria - patients, the researchers successfully applied their method to adult mesenchymal stem cells, which can differentiate into a variety of cell types, including adipocytes, osteoblasts, chondrocytes, cardiomyocytes, and, as described lately, beta - pancreatic islets cells.

All the more as of late, it has been found that expanding dietary protein raises the circling level of insulin - like development factor - 1, a development factor that advances osteoblast arrangement and bone development.

The reasoning goes as follows: estrogen is a sex hormone that is essential to female bone health because it promotes the activity of osteoblasts, which are cells that produce bone.

Although adiponectin's signaling pathways are generally thought to be distinct from those of insulin, in this case it acts through the same signaling pathway as insulin in both osteoblasts and in the brain.

Over time heavy impact work increases the activity of osteoblasts within your body which in turn leads to bigger and stronger bones — now this might not be something you've considered but when you get to middle aged, or elderly, and you fall over you might find yourself thankful for your years of pumping iron as you will likely walk away far less injured then your more sedentary friends.

The Opotowski team, which found that low vitamin A levels had as great an effect lowering BMD as did high vitamin A levels, suggested that vitamin A deficiency may contribute to increased fracture risk by allowing bone matrix to grow faster than it can be mineralized.12 Indeed, although the net effect of vitamin A is to stimulate osteoclasts and slow the growth of osteoblasts, vitamin A also causes osteoblasts to secrete a variety of enzymes and other proteins that are important to bone mineralization, including osteocalcin, which is a protein that plays a direct role in attracting and binding calcium within the bone matrix.6 By slowing the growth of the matrix but increasing the rate at which it is mineralized, adequate vitamin A helps to ensure sufficient bone density.

Here's a quote: «Lactoferrin: Lactoferrin found in foods such as yogurt and kefir will stimulate new bone growth while preventing further breakdown of existing bone tissue, lactoferrin enhances both the growth and the activity of osteoblasts (the cells that build bone), and reduces the rate of bone cell death by 50 to 70 percent and decreases the development of osteoclasts, the cells responsible for breaking down bone.»

I think that probably the signs of pano or the actual development of enostosis, as some prefer to call it, in the hemophiliac dog come about via bleeding in the marrow with osteoblast (bone depositing cells) activity.

Effects on osteoblasts are relevant to cartilage health as changes brought about by mediators on the bone underlying cartilage, known as subchondral bone, can lead to breakdown of cartilage.

Endogenous sex steroids such as estrogen and testosterone may serve as prodifferentiation agents that inhibit the malignant transformation of osteoblasts (31).