Not exact matches
Pair bonding may not be the best or only way to serve our
genes but then there is no reason why we have to accept the so called «selfish
gene» theory, that we are of value only as gene carriers (the theory popularised by Richard Dawkins in The Selfish G
gene» theory, that we are
of value only
as gene carriers (the theory popularised by Richard Dawkins in The Selfish G
gene carriers (the theory popularised by Richard Dawkins in The Selfish
GeneGene.
Damage to human chromosome 9 (
of the cell's 24
pairs) where the
gene that codes for E-NTPDase2 resides is known to cause eye and brain defects, such
as microphthalmia — literally, small eyes.
They started with
pairs of fat yellow mice known to scientists
as agouti mice, so called because they carry a particular
gene — the agouti
gene — that in addition to making the rodents ravenous and yellow renders them prone to cancer and diabetes.
While chimps have only two copies
of the salivary amylase
gene (one on each
of the relevant chromosome
pair), humans have an average
of six, with some people having
as many
as 15 (Nature Genetics, vol 39, p 1256).
By using
pairs of sisters who spent differing amounts
of time living with their fathers, the study was able to control for inherited
genes and environmental conditions, such
as socioeconomic status or religious background, to isolate the effects
of fathering quality on daughters.
Yin is the corresponding author
of a study published in the peer - reviewed academic journal Nature Communications, which shows those interactions depend on a
pair of genes known
as BES1 and RD26.
But in
genes, differences
as small
as a point mutation — the alteration
of a single base
pair — can lead to disease.
They found up to seven variations
of the
gene — some differing by
as much
as 25 %
of their base
pairs — in a single snail.
«But perhaps the most exciting implication is that our tools, when
paired with appropriate activity modulator
genes, could enable non-invasive deep brain modulation for the treatment
of neurological diseases such
as Parkinson's disease.»
To show that technique worked, the scientists used DropSynth to make thousands
of bacterial
genes — each
as long
as 669 base
pairs in length.
Besides promoters located in the beginning
of genes,
gene expression is also regulated by enhancers which may be located
as far
as thousands
of base
pairs away from the
gene they regulate.
The human genome contains about 3 billion base
pairs, but only about 2 percent
of these base
pairs represent protein - coding
genes, meaning that whole - exome sequencing measures the genetic alterations focused on a small but very important fraction
of the genome (
as opposed to techniques
of whole genome sequencing, which measures every nucleotide across the entire genome, regardless
of whether these
genes are expressed or silent).
«This is the first study to examine mate choice among wild - spawning fish
of both hatchery and wild origin, and the results suggest that greater diversity
of immune
genes between wild - born
pairs of coho salmon may increase offspring survival,» said Amelia Whitcomb, who did the research
as a master's student at OSU and is lead author on the publication.
But the newly identified virus, known
as the Cafeteria roenbergensis virus, is a pack rat: It lugs around a staggering 730,000 base
pairs of DNA, including more than 500
gene - like regions, researchers report online today in the Proceedings
of the National Academy
of Sciences.
However, further sequencing analysis established that these germ line chimera were not present at the earlier time point,
as no sequences with the fully mature DJ regions
paired to the relevant germ line V
genes were detected at t = 54 whereas between 50 and 250 copies
of such clones were present at t = 174.
The remaining 2
pairs of primers, both derived from highly conserved sequences in the hexon
gene [26], [28], were able to detect TMAdV in culture
as well
as directly from clinical material.
The upper panel shows the distance
of read
pairs; the insertion
of the region probably occurred after the duplication
of the
gene into the subtelomeres,
as all reads from the duplications are connected over the insertion.
Stem cell researchers from UCLA used a high resolution technique to examine the genome, or total DNA content,
of a
pair of human embryonic stem cell lines and found that while both lines could form neurons, the lines had differences in the numbers
of certain
genes that could control such things
as individual traits and disease susceptibility.
Rather, HAR2 functions
as an enhancer, a DNA sequence that works to increase or decrease the level
of a
gene's expression.8 An enhancer can be located thousands
of base
pairs away from the
gene it regulates.
For more than a century, geneticists have known that, in organisms that
pair up to reproduce, most
genes have a 50 - 50 chance
of being inherited,
as Gregor Mendel famously showed in the 19th century with pea plants.
In the study, Setton and Sharma show that a
pair of genes, known
as Sp6 - 9 and Dll, normally involved in telling a developing insect or arachnid embryo where to grow legs, has been co-opted by a group
of arachnids to also help tell the embryo where to build its head.
The team's RGB system consists
of 18
genes, 14 promoters,
as well
as other bits
of DNA called terminators and plasmids, and 46,198 base
pairs.
But Spector argues that EpiTwin has already made valuable contributions — for example, through a study
of 15 twin
pairs discordant for breast cancer that pointed toward hypermethylation
of the DOK7
gene, which he believes could one day be used
as a biomarker to help identify women at risk for breast cancer years in advance.
During his long and fruitful
pairing with
Gene Siskel, Ebert stoked that passion
as the two frequently clashed on camera over a movie's merits, becoming the most popular and influential film critics
of their — and probably any — era.
Saturday brings a
pair of classics named after the dames that haunt our heroes: Gilda (1946), starring Rita Hayworth in her most iconic screen siren role
as a sex kitten who digs her claws into the bodyguard (tough guy Glenn Ford)
of her crippled sugar daddy husband (George Macready), and Laura (1944), with
Gene Tierney
as the beauty in a painting who obsesses homicide detective Dana Andrews.
Within each cell in the body,
genes are present
as pairs one on each
of two strands
of DNA (chromosomes).
These
genes are put together in
pairs as strains and form the 39 chromosome
pairs of a dog.
Not nearly
as simple
as those due to a single
pair of defective recessive
genes that some offspring inherit from their parents.
Although the visual effect can be the same, it is easy to confuse this with the subtle hint
of bronze (liver) that shows through in coats
of some black dogs that carry an incompletely - masked recessive allele (one
of the
gene pair) for «a dilute» such
as liver - chocolate.
The heart
of the innovation,
as I understand it, lies in the choice
of a particular and small region
of DNA shared by many animals; to say it in technical terms: it's «a 648 base -
pair region in the mitochondrial cytochrome c oxidase 1
gene («CO1»).»