Current approaches focus on anticipation and prevention of pain, as well
as both pharmacologic and nonpharmacologic management techniques.
Residency programs encompass most veterinary clinical specialties as well
as pharmacologic, pathologic, and toxicologic fields.
Not exact matches
Wait, did you just quote the NLM saying that red clover in
pharmacologic amounts is likely unsafe in pregnancy
as support for your giving it to pregnant women?
Bierut: So there are multiple different pathways to alcoholism and some of them are
pharmacologic - type pathways of how a person metabolizes alcohol — how they respond to it with the alcohol dehydrogenase or acetaldehyde dehydrogenase, two important enzymes that are involved in the metabolism of alcohol, and we would kind of think [of] that
as a more direct alcohol - related route to the development of alcoholism.
«We wanted to use
pharmacologic means to get the same effect
as the gene variant,» says Alban Latremoliere, PhD, also of Boston Children's Kirby Center, who led the current study along with Woolf and Costigan.
«Our results suggest that
pharmacologic targeting of the CB with a CSE inhibitor, such
as L - PAG, might prevent apneas.»
«Nonetheless,» they conclude, «
pharmacologic modulation of the CB chemoreflex by an inhibitor of H2S synthesis,
as shown in the present study, has the potential to significantly improve the clinical management of sleep apnea.»
Referral to other
pharmacologic and non-
pharmacologic therapies also were agreed upon
as possible management options, but access to these treatments may be limited based on availability.
«While most
pharmacologic treatment for depression target monoamine systems, such
as serotonin, dopamine and norepinephrine, this intervention targets the parasympathetic and gamma aminobutyric acid system and provides a new avenue for treatment.»
The findings, which appear in the Journal of Alternative and Complementary Medicine, provide preliminary support for the use of yoga - based interventions
as an alternative or supplement to
pharmacologic treatments for depression.
The article, published in CMAJ (Canadian Medical Association Journal) looks at the latest
pharmacologic research
as well
as disease - modifying agents and the benefits and risks of various treatments.
In the study, the research team presented a novel
pharmacologic candidate that alleviates age - related degenerative joint conditions, such
as osteoarthritis (OA) by selectively destroying SnCs.
Most of his work focuses on the
pharmacologic manipulation of mammalian brain circuits which use the most abundant inhibitory neurotransmitter in the central nervous system gamma - aminobutyric acid (GABA)
as their chief signaling molecule.
Moreover, large - scale screens in the C. elegans DMD model allowed identifying genetic and
pharmacologic suppressors of dystrophin - dependent muscle degeneration; some of them positively impact mitochondrial functions or structure under stress conditions, or are involved in signaling pathways linked to mitochondria, and others are associated to proteostasis pathways such
as autophagy, proteasome and Unfolded Protein Response (UPR).
This prompted us to characterize in more detail shared mechanisms and pathways and to target them with genetic and
pharmacologic means so
as to identify some broadly efficient suppressors of muscle degeneration.
Competitive pathway analysis implicated the biological processes of neurogenesis and synaptic regulation,
as well
as the gene targets of two
pharmacologic agents: cinnarizine, a T - type calcium channel blocker, and LY97241, a potassium channel inhibitor.
Pharmacologic doses are used clinically to treat specific diseases and need a doctor's prescription; physiologic (or nutritional) doses are used to improve or maintain optimal health, such
as in dietary supplements.
Antioxidants such
as Vitamins E and C may have a
pharmacologic benefit during exercise of athletic dogs, inhibiting free radical production during rigorous exercise.
Pain is best managed from a multimodal perspective, which means using various techniques — both
pharmacologic (medications)
as well
as nonpharmacologic — in conjunction to achieve the goal of maximum comfort.
Pharmacologic intervention should only be considered
as a last option and only
as a part of an overall weight loss program because all too often people rely on the drug to do all the work and do not make the necessary lifestyle modifications of eating less and moving more.»