Not exact matches
«This is a very important discovery that will guide future research efforts to explore the interactions of these
pigmentary genes with other genetic and environmental risk factors in cancers not linked to sun exposure, such
as eye melanoma.
Although many of the components of this syndrome, such
as cognitive, sensory, and motor disabilities, are shared by other congenital infections, 5 features differentiate CZS from other congenital infections: (1) severe microcephaly with partially collapsed skull; (2) thin cerebral cortices with subcortical calcifications; (3) macular scarring and focal
pigmentary retinal mottling; (4) congenital contractures; and (5) marked early hypertonia with symptoms of extrapyramidal involvement (Table).
There has been a great deal of discussion regarding
pigmentary uveitis since it was first described
as a disease of Golden Retrievers (Sapienza et al, 2000).
We have to be absolutely sure that the Goldens we think are clear of
pigmentary uveitis truly are clear
as we start screening genes.
Many dogs have
pigmentary changes
as they grow older.