The researchers reprogrammed the cells to create induced pluripotent stem cells in an FDA - compliant facility at the Broad Stem Cell Research Center; the use of this facility is an important step in the process
as preclinical research moves toward human clinical trials.
Not exact matches
• Changes may be afoot for biomedical scientists
as a result of efforts at the National Institutes of Health (NIH) to improve the reproducibility of
preclinical research.
The
research into quantum dots containing single magnetic ions was funded with grants from the Polish National Science Centre and the Polish National Centre for Research and Development, as well as project funds from the Centre for Preclinical Research and Tec
research into quantum dots containing single magnetic ions was funded with grants from the Polish National Science Centre and the Polish National Centre for
Research and Development, as well as project funds from the Centre for Preclinical Research and Tec
Research and Development,
as well
as project funds from the Centre for
Preclinical Research and Tec
Research and Technology.
Recently published in the journal eLife and featured in a poster session at this year's American Association for Cancer
Research (AACR) annual meeting,
preclinical experiments show for the first time that PLK1 promotes the migration of prostate cancer cells by setting in motion a process that induces what is known
as the epithelial - to - mesenchymal transition (EMT).
Until now, those programs were managed by the National Human Genome
Research Institute (NHGRI) under the direction of Christopher Austin; he will serve
as director of the NCATS
preclinical division.
These encouraging
preclinical results suggest the compound, known
as GS - 5734, should be further developed
as a potential treatment, according to
research findings to be presented tomorrow at the IDWeek conference.
Finally, the wide diffusion of some of these diagnostic techniques in the clinical practice, such
as MR, US and CT, makes these tools a valuable translation bridge between
preclinical research and clinical trials.
Janssen GPH will also prioritise work with the International Partnership for Microbicides developing the investigational drug dapivirine for use
as a monthly vaginal microbicidal ring designed to prevent sexual transmission of HIV and continue its pact with Drugs for Neglected Diseases initiative for the
preclinical research of a reformulated form of flubendazole for lymphatic filariasis (elephantiasis) and onchocerciasis (river blindness), Janssen GPH is also developing a new, chewable formulation of Vermox (mebendazole) that will facilitate treatment of intestinal worms in younger children.
As an established, recognized
research facility, AGI has assisted our partners in conducting
preclinical primate
research studies in a variety of areas.
It enables scientists at Moderna's ventures and New Venture Labs,
as well
as our biopharma partners, to digitally design and order mRNA constructs for use in discovery
research and
preclinical studies through an encrypted and secure portal.
Having a strong R&D department with great experience and expertise in drug development, animal model and assay development and
preclinical efficacy evaluation, the contribution of Biomedcode has been greatly valued by our partners,
as documented by our participation in several collaborative
research projects.
As MD Anderson moves toward molecular characterization of the cancers of all our patients, allowing their optimal assignments to promising new targeted therapies and potential identification of biomarkers of response and resistance, the department's mission includes thematic translational
research and
preclinical molecular pathology
research.
Together, this translational program is developed within the National Cancer and Cognition Platform (CNO / Ligue Nationale contre le cancer), with the aim to collaborate in a structured way with French oncology groups,
research teams
as well
as pharmaceutical industry, by providing
preclinical models and guidance on standard operating procedures for ancillary or future studies in identified population at risk.
In an effort to further exploit the potential of Pexa - Vec to activate the immune system to fight cancer,
as seen in McDonald's
preclinical data, SillaJen recently announced a new clinical trial in collaboration with New York - based Regeneron Inc. to test Pexa - Vec and REGN2810, a PD - 1 checkpoint inhibitor, in combination against renal cell carcinoma, and recently signed a sponsored
research agreement with UCSF to enable joint support of parallel
preclinical experiments by McDonald's team.
They are mainly used in
preclinical tests, but also in basic biological
research,
as well
as in behavior and cognition programs.
Overall, SR - Tiget represents a multi-disciplinary
research environment, which provides a unique blend of scientific expertise in the development of innovative gene and cell therapy strategies, access to relevant
preclinical models to evaluate their efficacy and safety,
as well
as competence in conducting early phase clinical trials.
Thus, to support and enhance our collaborations with industry partners dedicated to improving the lives of children with nervous system disorders, the Translational Neuroscience Center (TNC) at Boston Children's Hospital has recruited Robin Kleiman, PhD,
as the head of
preclinical research.
Performs genome - wide profiling of vector integration sites
as readout of cell growth at clonal level, in basic
research studies and technology development, in
preclinical safety studies and in gene therapy treated patients.
He also served
as Executive Vice President for Worldwide Discovery and
Preclinical Research at Merck & Co..
Researchers at the Sanford Consortium for Regenerative Medicine have broad scientific goals in basic and
preclinical research,
as well
as preclinical development of discoveries.
Duke s
research will use patented multielectrode technology to directly measure the activity of hundreds of neurons to study brain dynamics in unique
preclinical models of diseases such
as Parkinson s and schizophrenia.
He was introduced to radiopharmaceutical development
as a postdoctoral
research associate and then
as a staff scientist in the department of radiology at Washington University School of Medicine, where he developed several
preclinical imaging agents to study brain tumors, atherosclerosis and Alzheimer's disease.
Sharing such information could irreparably harm our stockholder's AV411 asset by devaluing any competitive advantage that we currently hold through extensive know - how in the areas
preclinical and clinical
research,
as well
as intellectual property.