Sentences with phrase «as predictive biomarkers»
GeneAssess, Inc., is dedicated to developing its breakthrough discovery of the FRY gene as a predictive biomarker for breast and other cancers.
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As a Genentech spokesperson told me at the time: «Despite looking at hundreds of potential predictive biomarkers, we do not currently have a way to predict who is most likely to respond to Avastin and who is not.»
The team's next avenue of research will be focused on identifying a «biomarker» that can identify this distinct suppressive cell elsewhere in the body — for example, in blood or other samples — as a potential predictive clinical tool to determine when these cells are present in patients, which currently can not be done.
In efforts to enhance pre-clinical drug testing, Thomas Gaddy of the University of Southern California, Los Angeles, and colleagues in the research group of Professor Stacey Finley investigated a potential predictive biomarker for a type of cancer drug known as anti-angiogenic therapy.
Therefore, it is useful to identify tumor features that can serve as «predictive biomarkers» to forecast how a person's tumor might respond to a particular treatment.
Major focus areas include human genome interpretation and genetic dissection of novel rare diseases, predictive genomic signatures of response to therapy — especially cancer therapy, and novel sequencing - based assays as biomarkers of disease.
As ER - α is considered a reliable biomarker in immunohistochemical analyses and is already used to guide endocrine treatment it would be a suitable treatment predictive marker for antiangiogenic therapies.
Batteries of biomarkers that measure allostatic load (also termed allostatic overload to highlight pathophysiology of the extreme)(38) tap into the major mediators of allostasis along with some key secondary outcomes, such as body mass index or waist — hip ratio and glycosylated hemoglobin (39), and provide a broad - based assessment of the dysregulation of these adaptive systems that has turned out to have predictive value in a variety of epidemiologic studies (40).