Sentences with phrase «as programmed cell death»

Unlike their healthy counterparts, cancer cells lack the mechanism that tells them to stop multiplying, as well as the process known as programmed cell death (aka «apoptosis»), which gets rid of unneeded cells.

The Altieri laboratory is interested in how tumor cells evade apoptosis — also known as programmed cell death — which is the process that normally causes dysfunctional cells to self - destruct.

Checkpoint inhibitors are monoclonal antibodies that target certain proteins that downregulate the immune system, such as programmed cell death protein 1 (PD - 1), programmed death - ligand 1 (PD - L1) and cytotoxic T - lymphocyte antigen 4 (CTLA - 4).

If this fails, the UPR instructs the cell to self - destruct, a process known as programmed cell death or apoptosis.

Not exact matches

During that year, and subsequent years spent as a postdoc in Morata's lab (and later with Konrad Basler at the University of Zurich, Switzerland), Moreno was able to link the previously isolated phenomenon of cell competition to the well - established process of programmed cell death.

The function of these genes were involved in molecular maintenance strategies, such as DNA repair, chromosomal maintenance, immune response and programmed cell death The authors argue that the «slower rate of change in these functions is consistent with increased constraint on somatic cell maintenance as would be required in these relatively long - lived and large - bodied mammals, illustrated by the additional large and long - lived species with slower rates in these genes (e.g. double - strand break repair gene XRCC4 is also highly constrained in elephant.»

The study, published by the journal Proceedings of the National Academy of Sciences, demonstrates that the Disney lab's compound, known as Targaprimir - 96, triggers breast cancer cells to kill themselves via programmed cell death by precisely targeting a specific RNA that ignites the cancer.

The American Society of Hematology Policy Statement on Screening for Sickle Cell Trait and Athletic Participation opposes mandatory screening of athletes for sickle cell trait as a prerequisite to athletic participation and urges athletics programs to adopt universal preventive interventions in their training programs to protect all athletes from exertion - related illness and deCell Trait and Athletic Participation opposes mandatory screening of athletes for sickle cell trait as a prerequisite to athletic participation and urges athletics programs to adopt universal preventive interventions in their training programs to protect all athletes from exertion - related illness and decell trait as a prerequisite to athletic participation and urges athletics programs to adopt universal preventive interventions in their training programs to protect all athletes from exertion - related illness and death.

John Reed, M.D., Ph.D., a world - recognized expert in programmed cell death and cancer, took over as president and CEO in 2001.

Paligenosis, Mills explains, appears similar to apoptosis — the programmed death of cells as a normal part of an organism's growth and development — in that it seems to happen the same way in every cell, regardless of its location in the body.

Biologists often view cancer primarily as a genetic program gone wrong, with mutations and epigenetic changes producing cells that don't behave the way they should: Genes associated with cell division and growth may be turned up, and genes for programmed cell death may be turned down.

Manuscripts that increase our understanding of the processes through which stem cells and progenitors differentiate into committed progeny, the commitment cell death programs such as apoptosis and necrosis, aging, and the transition between proliferation and cell cycle arrest are welcome.

The drugs reduce pain and inflammation by inhibiting the cyclooxygenase (COX) enzymes, which are involved not only with inflammation but also with certain processes involved in cancer, such as blood supply to the tumor and programmed cell death (known as apoptosis).

Earlier research suggests these compounds are able to negatively affect critical cancer cell mechanisms, such as those responsible for programmed cell death (apoptosis) and for proliferation.

Our friendly flora's digestion of fiber also yields another short - chain fatty acid called butyrate, which may fight against cancer by slowing the growth of colon cancer cells and activating programmed cancer cell death — as well as preventing cancer in the first place.

Abnormal Krebs cycle and / or oxidative phosphorylation cause (s) not only glucose hypometabolism but also the increased generation of reactive oxygen species (ROS), oxidative damage, and programmed cell death such as apoptosis.

In cancer therapy, melatonin counteracts chemotherapy toxicity, by acting as an anti-oxidant agent, and promotes apoptosis (programmed cell death) of cancer cells, thus enhancing the toxicity of chemotherapy.

This disease - fighting nutrient can slow the growth and development of new blood vessels that nourish tumors, increase a type of programmed cancer cell death known as apoptosis and reduce the proliferation of new cancer cells.

Rutin and gallic acid have been shown to induce apoptosis (programmed cell death) as well as complete destruction of cancer cells too.

The study team discovered that GSE targets colorectal cancer through inducing oxidative stress that leads to the programmed cell death known as apoptosis.