Sentences with phrase «as pyramidal cells»

Along the way the signal can be amplified by excitatory neurons such as pyramidal cells (PYRs) or dampened by inhibitory neurons such as SST and PV cells.

Fast - spiking interneurons are part of a general class of neurons whose primary role is regulating the activity of the principal cells of the cerebral cortex, known as pyramidal cells.

Not exact matches

BRAIN CANDY A new database offers a deep look at living human nerve cells, revealing elaborate branching structures and myriad shapes, such as in this neuron called a pyramidal cell (cell image, left and 3 - D computer reconstruction, right).

Neuronal activity is correlated with an influx of calcium ions, which can be tracked with fluorescent dyes or proteins that bind to calcium, as in these pyramidal cells.

To see what was happening in the brains of these ankyrin - G mutant mice, the researchers analyzed the cell components in inhibitory synapses connecting with pyramidal neurons, finding that two proteins known as GAT1 and GAD67 — responsible for making the neurochemical GABA that dials back nerve impulses — were at much lower levels in the synapses on pyramidal neurons in ankyrin - G mutant mice than in normal mice.

Cembrowski shared some clues as to what's ahead for him and his colleagues: «We have identified suspect number one in terms of what's responsible for the electrophysiological differences between subiculum pyramidal cells and we hope to investigate that, perhaps using gene editing.»

The inverse relationship between the amyloid plaque density and pyramidal cell density in the AD brain regions also supports this possibility, as does the close correlation between plaque size and the size of local pyramidal cells.

A beta 42 first selectively accumulates in the perikaryon of pyramidal cells as discrete, granules that appear to be cathepsin D - positive, suggesting that they may represent lysosomes or lysosome - derived structures.