Sentences with phrase «as reactive oxygen»

Also, a 2012 study published on the Medical Journal 3 Biotech shows that the anti-cancer compounds in mushrooms play a crucial role as a reactive oxygen species inducer, mitotic kinase inhibitor, antimitotic, angiogenesis inhibitor, topoisomerase inhibitor all leading to apoptosis (cell death) and eventually checking cancer cell proliferation (4).

Many types of free radicals exist, but oxygen - derived radicals, known as reactive oxygen species (ROS), are the most concerning.

But the process of producing ATP creates a huge burst of damaging free radicals known as reactive oxygen species (ROS), which are the chief cause of mitochondria destruction.

Cadmium interacts with cells of the immune system (neutrophils and macrophages) and promotes the release of free radicals such as reactive oxygen species.

While there are many types of free radicals that can be formed, the most common in aerobic (oxygen breathing) organisms are oxygen free radicals, often referred to as Reactive Oxygen Species (ROS), which include superoxides, hydroxyl anions, hydrogen peroxide and singlet oxygen.»

This causes the body to create unstable molecules known as reactive oxygen species (ROS).

Free radicals, otherwise known as reactive oxygen species, are a byproduct of metabolism.

Not exact matches

When potent oxygen radical scavengers such as cerium oxide nanoparticles (nanoceria) were combined with a highly charged polymer (polyacrylic acid) and incorporated into extracted chloroplasts using the LEEP process, damage to the chloroplasts from superoxides and other reactive oxygen species was dramatically reduced.

One lit up in the presence of hydrogen peroxide, a prominent reactive oxygen species, whereas the other two acted as mitochondrial injury sensors.

The find is one of the first signs that such reactive oxygen species can build as well as destroy.

The surprise to biochemists was that the enzyme, called FtmOx1, produces a highly reactive «helper» known as a free radical that assists in putting the oxygen atoms in the right place.

«Our work highlights the need to take a nuanced view of the role of reactive oxygen species, as they are necessary when they are present at the right place and right time.

«Energy production can also generate reactive chemical species — often referred to as «reactive oxygen species» or «oxidants» — as by - products, which can be damaging to cells.

Sunlight and toxins do much of the damage, but the biggest culprit may be highly reactive byproducts created as cells use oxygen to turn sugar into energy.

High glycolytic activity leads to accumulation of toxic reactive oxygen species (ROS), as does rapid manufacture of mitochondria, which tend to leak the same chemicals.

Macrophages, as part of the inflammatory response, produce reactive oxygen species in order to attack bacteria.

That light is absorbed by the chlorine - based molecules, which then excite nearby oxygen molecules, creating a highly reactive form of oxygen, known as singlet oxygen, that rips apart nearby biomolecules and kills the tumor cell.

The Einstein team suspected that cysteine was helping to kill TB bacteria by acting as a «reducing agent» that triggers the production of reactive oxygen species (sometimes called free radicals), which can damage DNA.

But organisms from humans to algae also have another clock that doesn't rely on rhythmic gene expression to keep time, but instead uses the rise and fall of the reactive oxygen molecules that are formed as natural byproducts of metabolism.

More research produced the answer: Vitamin C induced what is known as a Fenton reaction, causing iron to react with other molecules to create reactive oxygen species that kill the TB bacteria.

As we age, the nitric oxide meant to cause dilation is increasingly destroyed by reactive oxygen species such as superoxide, which are produced by many components of our body's own cells, including organelles called mitochondriAs we age, the nitric oxide meant to cause dilation is increasingly destroyed by reactive oxygen species such as superoxide, which are produced by many components of our body's own cells, including organelles called mitochondrias superoxide, which are produced by many components of our body's own cells, including organelles called mitochondria.

In this case, they form naturally as ozone — a high - energy oxygen molecule — reacts with carbon chains that have double bonds, forming a compound that has two reactive pairs of electrons.

That phenomenon, known as oxidative stress, occurs when the cells of older adults begin to produce too much superoxide and other reactive oxygen species.

Also, in both cell culture and a mouse model of the condition, blocking the excessive splintering reduced production of reactive oxygen species, a potentially harmful byproduct of metabolism, as well as cell death.

Physiologist Dino Giussani and colleagues at the University of Cambridge in the United Kingdom theorized that hypoxia promotes harm in the womb primarily through stress caused when the low level of oxygen creates an overload of highly reactive molecules known as free radicals.

Technology such as this, scientists said, may have a promising future in the identification and surgical removal of malignant tumors, as well as using near - infrared light therapies that can kill remaining cancer cells, both by mild heating of them and generating reactive oxygen species that can also kill them.

It can make a cell glow as a guide to surgeons; heat the cell to kill it; and produce reactive oxygen species that can also kill it.

Consequently, massive amounts of reactive gases such as oxygen, hydrogen, and methane are continually being added to Earth's now «anomalous» atmosphere faster than they would otherwise be removed by inorganic chemical processes.

I've been experimenting with T10 dextran coated iron oxide nanoparticles, obviously not the same as fullerenes, but still a very interesting tool, I've been testing if the coating is giving the particle antioxidant abilities because of it's the (basically) indigestable sugar chains (glucose) creating a high surface area which are largely made from hydroxyl groups, I hypothesised this act's as a «sink» for reactive oxygen species converting them to water.

The prevailing theory is that this reduces damage to mitochondria occurring as a result of the reactive oxygen species generated within these organelles, with localized antioxidants soaking up reactive molecules before they can cause harm.

Intracellular reactive oxygen species (ROS) levels were measured for all groups as described earlier [22].

DNA is constantly exposed to a variety of damaging factors such as genotoxic agents, environmental factors (e.g. UV light, irradiation) or normal metabolic activities (e.g. nucleotide misincorporation during DNA replication, reactive oxygen species) that causes a range of lesions.

At Emory, Kathy Griendling's group is well known for studying NADPH oxidases (also known as Nox), enzymes which generate reactive oxygen species.

Although many years ago we found that reactive oxygen species (ROS) are required for full expression of hippocampal LTP and memory, it is clear that the aged and diseased brain handle ROS much differently as many studies have pointed to a role for excessive ROS and oxidative stress in age - related cognitive decline and impaired memory associated with Alzheimer's disease (AD).

Over time however, mutations in these genes occur as a result of constant exposure to reactive oxygen species produced by oxidative phosphorylation, the mitochondrial energy generation process.

During the normal processes of metabolism the body generates what are called «reactive oxygen species» which are commonly referred to as «free radicals».

Mononuclear cells from the blood were isolated during the OGTTs to analyze if these cells were producing molecules known as ROS (reactive oxygen species).

Specifically, the research demonstrates that grape seed not only damages cancer cells» DNA (by means of an increase of reactive oxygen species), but also prevents the pathways which allow repair (as seen by reduced amounts of the DNA repair molecules Rad51 and Brca1 as well as DNA repair foci).

More than one hundred vitamin B6 - dependent enzymes have been identified, mostly involved in amino acid metabolism: for oxygen transport via hemoglobin synthesis; in blood sugar regulation via conversion of stored carbohydrate to energy; in the development of the myelin sheath surrounding nerve cells; in the conversion of alphalinoleic acid to the essential long - chain fatty acid DHA; 28 and in the synthesis of neurotransmitters, phospholipids and sphingolipids, the vitamin niacin from tryptophan, and other vital metabolites.5 In addition to its role in enzyme reactions, B6 appears to moderate the action of some steroid hormones such as the glucocorticoid hormones, which in turn influence the metabolism of protein, carbohydrate and lipids.5, 9 B6 also is a potent antioxidant, rivaling carotenoids and vitamin E in its ability to quench reactive oxidants in the body.29

However, the latter is preferred because it is a cleaner, healthier fuel, as it releases far fewer reactive oxygen species (ROS) and secondary free radicals.

Reactive Oxygen Species (ROS) and Reactive Nitrogen Species (RNS) are known as «free radicals» and have been shown to cause damage and death to the cells they come in contact with.

The immune defense against these infections is glucose - dependent (as it relies on production of reactive oxygen species using glucose) and thyroid hormone - dependent (as thyroid hormone drives not only glucose availability, but also the availability of iodine for the myeloperoxidase pathway).

Abnormal Krebs cycle and / or oxidative phosphorylation cause (s) not only glucose hypometabolism but also the increased generation of reactive oxygen species (ROS), oxidative damage, and programmed cell death such as apoptosis.

Research suggests that Vitamin C is a highly effective antioxidant and that small amounts can protect essential molecules in the body from free radical damage and reactive oxygen species generated during normal metabolism, as well as through exposure to toxins and pollutants.

It boosts the immune system, protects vision, stops the build - up of oxidised fats, and helps to convert carbohydrates into energy and most crucially reduces the damage done to important cell components caused by reactive oxygen molecules such as free radicals and peroxides7.

Various hypotheses have been put forward to explain the molecular reasons for aging, a prominent role among them being played by the free radical theory of aging.3, 4 Free radical components (reactive oxygen species or ROS) or lipid peroxide (LPO) is involved in the pathogenesis and progression of accelerated skin aging and chronic skin conditions such as acne vulgaris.

As a general rule, the shorter the carbon chain, the more efficiently the MCT will be turned into ketones, which are an excellent source of energy for your body — far preferable to glucose, as ketones produce far less reactive oxygen species (ROS) when they are metabolized to produce ATAs a general rule, the shorter the carbon chain, the more efficiently the MCT will be turned into ketones, which are an excellent source of energy for your body — far preferable to glucose, as ketones produce far less reactive oxygen species (ROS) when they are metabolized to produce ATas ketones produce far less reactive oxygen species (ROS) when they are metabolized to produce ATP.

Their protective abilities extend to the brain as well — brain tissue treated with acai shows that anthocyanins can limit the ability of reactive oxygen species to damage essential brain lipids and proteins.

Reactive oxygen species (ROS) are not universally bad, and one of their important functions is to signal the body to increase protein synthesis as part of the mTOR pathway.

Known as «delayed onset muscle soreness» (DOMS), we typically experience these pains when eccentric muscle activity is involved and the contracting muscles are forcibly lengthened.1 This mechanical stress triggers an inflammatory response and the production of reactive oxygen species (ROS).