Performs genome - wide profiling of vector integration sites
as readout of cell growth at clonal level, in basic research studies and technology development, in preclinical safety studies and in gene therapy treated patients.
Finally, the study suggests new tumorigenic and cellular functions of BAP1 and shows for the first time the interest of studying the proteome
as readout of BAP1 inactivation.
The use of endogenous HMOX1 protein expression
as a readout allowed the identification of compounds that specifically derepress Bach1 and induce transcription of an Nrf2 - responsive gene.
Recently, GlaxoSmithKline isolated an RIPK2 inhibitor, GSK - 583 (6 -(tert - butylsulfonyl)- N -(5 - fluoro - 1H - indazol -3-yl) quinolin -4-amine), based on using the full RIPK2 protein to screen a DNA - encoded library collection with a fluorescence polarization — based binding assay
as a readout (Haile et al., 2016).
At the end of the experiment, counting the numbers of each barcode serves
as a readout that reveals how many cells from each cell line survived exposure to the compound.
In addition, part of SciLifeLab bioinformatics platform is extensively dealing with sequencing data and increasingly many other SciLifeLab platforms require sequencing services or use sequencing
as a readout.
Superresolution localization of single functional ip3r channels utilizing ca2 + flux
as a readout.
A further direction for researchers is to determine whether PCR testing for a panel of latent viruses could be used
as a readout of the state of a person's immunity.
Alternative methods, such
as readout of gene sequences, which is also done in paternity tests, are very time - consuming and expensive.
We use the behaviors that express those states
as a readout.»
Not exact matches
However, the reviewers noted that this is a fairly basic scale that lacks popular features such
as body fat
readouts and user profiles.
With his subsequent usher textbooks, autobiography (There Is life Beyond Name Tags, Dude Books, 2001), magazine (Badge and Bulletin, the only ushering magazine including a centerfold portrait) and cultlike following, Glibface had almost singlehandedly brought ushering into the sunlight of ecclesiastical celebrity ~ To his fame are credited such innovative strategies
as parhug valets; tour guides, computerized seating
readouts - for latecomers, and Roy Dude University's School of Usherology.
The new
readout came
as the economy continued showing signs of improvement and the tumultuous battle over the health care law that President Barack Obama finally signed in March faded into the background.
The paper - thin, credit card - size sensors on meat packaging may display text such
as, «Eat in X days,» or have a simple color
readout: green (safe), yellow (eat soon) or red (time for the trash).
Chief engineer Dave Munroe fiddles with a bolt
as he watches the cable
readout.
'» Indeed, some critics these days dismiss Damasio's once revolutionary ideas
as old news — an updated version of William James, who famously argued in the late 1800s that emotions were simply a
readout of the body's physiological state.
As a result, the
readout of your telomere length test won't come with detailed information about what to do about it.
One way to get many types of cells or proteins from the same genetic starting material is by mixing and matching different parts of one gene to produce multiple gene
readouts, a phenomenon known
as alternative splicing.
«This collaborative multi-disciplinary effort identifies «mitochondrial genome integrity»
as a vital
readout in assessing the proficiency of patient - derived regenerative products destined for clinical applications,» adds study co-author Andre Terzic, M.D., Ph.D., Director, Mayo Clinic Center for Regenerative Medicine.
These tags are detected and measured using a sensitive DNA analysis technique known
as massive, parallel sequencing, providing a quantitative
readout of the gene's activity levels.
He's excited to see a clear
readout for a process that would otherwise require decoding a complex pattern on a microarray, and he thinks the idea of simple alphanumeric display could be applied to other types of molecular logic
as well.
Readouts can show how a person responds to specific situations such
as jogging on a treadmill, weight lifting, and shopping for groceries.
The major obstacle, to my mind, is creating error - correcting software that can keep data from being corrupted
as the calculation proceeds toward the final
readout.
«So there is plenty of space to intersperse the key classical components such
as interconnects, control electrodes and
readout devices, while retaining the precise atom - like nature of the quantum bit.»
The MSC is a core facility providing the use of high throughput screening technology (HTS),
as well
as expertise and reagents, necessary for the screening of the library of small molecules for biologically active compounds in a variety of
readout systems.
Normalized (QNORM): The shape of the expression profile for each cell line is normalized such that all of the data for the collection is on the same scale (4
as minimally / not expressed, 15
as a maximum
readout).
As a bioinformatician, I have the unfortunate duty of informing you that we haven't yet reached the point you saw in GATTACA: no machine yet exists to predict someone's entire medical future from the
readout of their genetic code.
The
readout that is measured in contextual and cued fear conditioning is a freezing response that occurs following the pairing of an unconditioned stimulus such
as a foot shock, with a conditioned stimulus such
as a particular context or cue (tone).
The cell assays are based on blood samples or tissue biopsies from these patients, and
readouts are either specific, such
as antibody production or the production of proinflammatory cytokines, or wider, such
as proteomic effects of the probes.
Golub's team used a barcode
readout system, which had been «battle - tested» in work with DNA, RNA, and proteins previously,
as a basis for the method.
We simulate a CCD
readout with CTI such
as that caused by charged particle radiation damage.
According to Dr. Gilberto Leon, a holistic medicine doctor who interpreted the EKG
readout at the scene, irregularities such
as these can overwork the heart, causing fatigued cardiac function.
The review board's report details numerous alleged instances in which Das improperly combined results from several experiments by altering a type of digital data
readout known
as a Western blot.
As in other AMG cars, the SLS offers performance - oriented in - dash
readouts for coolant, engine - oil, and gearbox - oil temperatures; the stability control setting; and the most recent lap and trip times.
(On my first night with the c, I took the interstate to get home and on the final curve on the entrance ramp, I flattened the throttle and watched
as the digital speed
readout slowly crept up one mile per hour, sometimes two, at a time.)
As a result, you'd think a car like the 911 R would ditch the high - tech setup to help the
readout on a scale.
The ST also gets variable - ratio sport steering, which is quite light at low speeds but firms up nicely
as the mph
readout rises.
On some cars the various trip computer settings can be cycled through to see an oil life remaining
readout - normally given
as a percentage.
Five of these turbine - bladed vents across the interior seem a bit much, but they ought to provide all the airflow anyone could want, and their centers serve
as controls and informational
readouts.
The digital speedometer and gear indicator are ringed by a tach
readout that turns yellow
as you approach the redline at 6500 rpm.
For the R / T Road & Track edition at $ 36,990, key additions include heavy - duty brakes and track suspension, 20 - inch cast aluminum wheels, a 3.07 rear - axle ratio, HID headlamps, the charming Performance Page
readouts and recorders, and interior goodies such
as leather - and - Alcantara performance seats.
Thanks to temperatures in the 30s, estimated range on the dashboard
readout could start
as low
as 36 miles, even after a full recharge.
As for how fast the Urus goes in a straight line on the skidpad's clean tarmac, less than 3.7 seconds to 62 mph is the official word, but 3.35 seconds is what the digital in - dash
readout says on location.
Some vehicles will have a dashboard
readout of service codes
as well.
Driver Information Center, with programmable personalization features such
as door locking and unlocking, a trip computer that contains trip odometer and individual tire pressure
readouts, fuel information such
as range, average mpg, gallons used and oil life and a message center that displays dozens of system messages such
as low fuel, door ajar, security, seat belt reminder, low coolant and oil pressure low
The elegant design incorporates the controls
as well, showing the climate
readout in the vent dial, and using the housing to control adjust temperature, seat heat and more.
As some consolation, the full - color instrument panel - mounted driver information display does give text
readouts of current - and upcoming road names.
Color schemes include black on black, plus a black on ivory two - tone,
as well
as a digital
readout behind the three - spoke steering wheel.
Only a large digital speed
readout is evident,
as the myriad of warning lights remain dark until trouble arises.
Ride along and watch the VBox
readouts as we run a Chevrolet Corvette Z06 around a lap of GingerMan Raceway in southwest Michigan.