Sentences with phrase «as scrapie»

Although endemic in Europe for centuries, the sheep disease known as scrapie achieved notoriety only during the 1980s, when it was apparently transmitted to cows in Britain via infected sheep remains in cattle feed, thereby causing mad cow disease.

They found that although the protein stayed soluble for a week or two, it eventually polymerized into long fibers resembling those in so - called prion diseases — brain diseases such as scrapie in sheep, «mad cow disease» in cattle, and Creutzfeldt - Jakob disease in humans.

Not exact matches

Prion specialist Moira Bruce of the Institute for Animal Health's Neuropathogenesis Unit in Edinburgh says that sheep experimentally infected with BSE become ill about as fast as sheep naturally infected with scrapie.

Degenerative brain diseases like mad cow disease (officially known as bovine spongiform encephalopathy, or BSE), scrapie in sheep, and vCJD in humans are thought to be caused by prions, misfolded versions of a normal cellular protein called PrPC.

Infamous for causing fatal degenerative brain diseases, such as bovine spongiform encephalopathy, known more commonly as «mad cow disease,» Creutzfeldt - Jakob disease, and scrapie, prions are proteins that have the ability to self - perpetuate when they assume a particular conformation.

Scientists have located two possible receptors for the so - called prion protein (PrP) believed to be at fault in fatal neurological conditions such as «mad cow disease,» Creutzfeldt - Jakob disease in humans, and scrapie in sheep.

It cause animal brains to turn into a spongy mess in scrapie, a disease of sheep, and in bovine spongiform encephalopathy (BSE or «mad cow disease»), as well as in human prion diseases such as CJD.

The new finding offers direct, physical evidence supporting protein - based inheritance, thus strengthening the «prion hypothesis» of the cause of neurodegenerative diseases in mammals, such as sheep scrapie, mad cow disease (or bovine spongiform encephalopathy) and the kuru disease of the Papua New Guinea tribes.

Dr. Cezar started her career at APHIS serving as a Veterinary Medical Officer, a role under Veterinary Services, where she worked firsthand in surveillance of critical public health diseases such as Chronic Wasting Disease and Scrapie.