Sentences with phrase «as thalassemia»

Exceptionally well - versed in genetics and hematology, with great focus on determining blood diseases such as Thalassemia and Leukemia.

Mia's statement above reminded me of an inherited trait I have which is Mediterranean anemia: Better known today as thalassemia (or as beta thalassemia or thalassemia major).

The Bone Marrow and Stem Cell Transplant Program is expanding the use of this technique for patients with solid tumors including neuroblastoma and brain tumors; a variety of high - risk hematologic diseases, such as thalassemia major and transfusion - dependent sickle cell disease; and other nonmalignant diseases.

Gene editing techniques have the potential to treat blood disorders that run in families, such as thalassemia and sickle cell anemia, but their application has been largely limited to cells in a laboratory and not living animals.

But Knutson does see this finding as more relevant for possibly treating other incurable iron overload disorders such as thalassemia.

Not exact matches

In many states, the test is required and is frequently done in conjunction with several other tests, such as Galactosemia, Thalassemia, etc..

Cord blood transplants are also accepted as treatment for thalassemia and sickle cell anemia, inherited blood disorders that are prevalent in certain ethnic groups.

Even today, such thalassemias occur relatively frequently in former malaria regions, such as the Mediterranean.

Harvard Stem Cell Institute (HSCI) scientists have taken the first steps toward developing a treatment that would make bone marrow — blood stem cell — transplantation safer and, as a result, more widely available to the millions of people living with blood disorders like sickle cell anemia, thalassemia, and AIDS.

Notably, research groups might be able to apply the approach described in this study to develop treatments for other blood diseases such as β - thalassemia, severe combined immunodeficiency (SCID), chronic granulomatous disease, rare disorders like Wiskott - Aldrich syndrome and Fanconi anemia, and even HIV infection.

Other plans include using CRISPR to reverse blood disorders, such as sickle cell anemia and beta thalassemia, caused by mutations in the hemoglobin gene.

However a human could rationalise the faulty belief by reinterpreting the metaphor in a newspaper style as «the cure for the political turmoil that beset the inhabitants of thalassemia».

The most common type in the United States is b thalassemia, also known as Mediterranean anemia in its mild form or Cooley's anemia in its severe form.

This causes only mild thalassemia, but because other genes are deleted as well, there are additional problems — such as birth defects and mental retardation — that do not occur in most thalassemias.

Because changes in the b globin gene are common in the Mediterranean area, people whose ancestors came from such areas as Greece or Italy may wish to be screened for thalassemia.

«For example, despite matching the ABO blood group antigens during red blood cell (RBC) transfusion, up to 45 percent of chronically transfused patients, such as those with sickle cell disease or thalassemia, develop antibodies to mismatched minor antigens on transfused RBCs; this process is known as alloimmunization.»

CRISPR / Cas9 could be used to develop therapies for humans for genetic blood diseases such as sickle cell or thalassemia, and this paper does not change that potential.

The hypothesis is eminently testable as iron reduction therapy is useful for chronic diseases associated with iron excess such as nonalcoholic steatohepatitis (NASH), atherosclerosis, hereditary hemochromatosis and thalassemia.

She is registred to the National Order of Biologists in the province of Palermo; collaboration in research project from 2012 to 2015 at the Department of Biopathology and Biotechnology, University of Palermo, focusing the study on the identification of molecules capable to modulate intracellular metabolic pathways for the prevention and treatment of infectious, tumor and degenerative disease, in collaboration with Prof. Angela Santoni, University of Rome; collaboration in research project in 2011 at the hospital «Villa Sofia Cervello» of Palermo to study methods can cure the genetic defect that causes thalassemia through genetic engineering; she studies different mechanisms of the differentiation and the activation of human gammadelta T cells as effector cells of the immune response against cancer and infectious diseases; she investigates about the identification and development of biomarkers of resistance and susceptibility to Mycobacterium tuberculosis infection; Valentina Orlando has published 13 papers in peer reviewed journals and 3 comunications at national and international congress.

Gene editing has emerged as a promising strategy to treat diseases like β - thalassemia and sickle cell disease which are both caused by mutations in the gene for β - globin (HBB).

Clinical research activities are focused on the implementation of experimental protocols based on gene or cell therapy for the treatment of genetic blood disorders such as ADA - SCID, Wiskott - Aldrich Syndrome, Metachromatic Leukodystrophy, Beta - thalassemia, Chronic granulomatous disease, Mucopolysaccharidosis Type I (Hurler).

An authority on the study and treatment of childhood cancers, as well as the biology and therapy of hemoglobinopathies — blood diseases such as sickle cell anemia and thalassemia — Cunningham is known for his work on understanding the molecular mechanism underpinning red blood cell production.

Beta thalassemia is a genetic disorder characterized by anemia and fatigue as well as bone deformities and organ problems.

However, keep ALL iron supplements away from children, even carbonyl iron, and do not take any kind of iron supplement if you have hemochromatosis, hemosiderosis or hemolytic anemia such as sickle cell anemia or thalassemia (aka Mediterranean anemia, a type of genetic anemia where hemoglobin is not well formed)

Less than 2 % of diseases, such as cystic fibrosis, Huntington's chorea, and beta thalassemia, result from a single faulty gene, and only about 5 % of cancer patients can attribute their diseases to heredity.