Sentences with phrase «as time necessary»

Although Southern blot analysis has proved to be a gold standard method in the detection of clonal rearrangement, it has several technical disadvantages, such as time necessary to obtain results, the use of radioactivity, and the susceptibility of the method to various artifacts [5].

Not exact matches

Important factors that could cause actual results to differ materially from those reflected in such forward - looking statements and that should be considered in evaluating our outlook include, but are not limited to, the following: 1) our ability to continue to grow our business and execute our growth strategy, including the timing, execution, and profitability of new and maturing programs; 2) our ability to perform our obligations under our new and maturing commercial, business aircraft, and military development programs, and the related recurring production; 3) our ability to accurately estimate and manage performance, cost, and revenue under our contracts, including our ability to achieve certain cost reductions with respect to the B787 program; 4) margin pressures and the potential for additional forward losses on new and maturing programs; 5) our ability to accommodate, and the cost of accommodating, announced increases in the build rates of certain aircraft; 6) the effect on aircraft demand and build rates of changing customer preferences for business aircraft, including the effect of global economic conditions on the business aircraft market and expanding conflicts or political unrest in the Middle East or Asia; 7) customer cancellations or deferrals as a result of global economic uncertainty or otherwise; 8) the effect of economic conditions in the industries and markets in which we operate in the U.S. and globally and any changes therein, including fluctuations in foreign currency exchange rates; 9) the success and timely execution of key milestones such as the receipt of necessary regulatory approvals, including our ability to obtain in a timely fashion any required regulatory or other third party approvals for the consummation of our announced acquisition of Asco, and customer adherence to their announced schedules; 10) our ability to successfully negotiate, or re-negotiate, future pricing under our supply agreements with Boeing and our other customers; 11) our ability to enter into profitable supply arrangements with additional customers; 12) the ability of all parties to satisfy their performance requirements under existing supply contracts with our two major customers, Boeing and Airbus, and other customers, and the risk of nonpayment by such customers; 13) any adverse impact on Boeing's and Airbus» production of aircraft resulting from cancellations, deferrals, or reduced orders by their customers or from labor disputes, domestic or international hostilities, or acts of terrorism; 14) any adverse impact on the demand for air travel or our operations from the outbreak of diseases or epidemic or pandemic outbreaks; 15) our ability to avoid or recover from cyber-based or other security attacks, information technology failures, or other disruptions; 16) returns on pension plan assets and the impact of future discount rate changes on pension obligations; 17) our ability to borrow additional funds or refinance debt, including our ability to obtain the debt to finance the purchase price for our announced acquisition of Asco on favorable terms or at all; 18) competition from commercial aerospace original equipment manufacturers and other aerostructures suppliers; 19) the effect of governmental laws, such as U.S. export control laws and U.S. and foreign anti-bribery laws such as the Foreign Corrupt Practices Act and the United Kingdom Bribery Act, and environmental laws and agency regulations, both in the U.S. and abroad; 20) the effect of changes in tax law, such as the effect of The Tax Cuts and Jobs Act (the «TCJA») that was enacted on December 22, 2017, and changes to the interpretations of or guidance related thereto, and the Company's ability to accurately calculate and estimate the effect of such changes; 21) any reduction in our credit ratings; 22) our dependence on our suppliers, as well as the cost and availability of raw materials and purchased components; 23) our ability to recruit and retain a critical mass of highly - skilled employees and our relationships with the unions representing many of our employees; 24) spending by the U.S. and other governments on defense; 25) the possibility that our cash flows and our credit facility may not be adequate for our additional capital needs or for payment of interest on, and principal of, our indebtedness; 26) our exposure under our revolving credit facility to higher interest payments should interest rates increase substantially; 27) the effectiveness of any interest rate hedging programs; 28) the effectiveness of our internal control over financial reporting; 29) the outcome or impact of ongoing or future litigation, claims, and regulatory actions; 30) exposure to potential product liability and warranty claims; 31) our ability to effectively assess, manage and integrate acquisitions that we pursue, including our ability to successfully integrate the Asco business and generate synergies and other cost savings; 32) our ability to consummate our announced acquisition of Asco in a timely matter while avoiding any unexpected costs, charges, expenses, adverse changes to business relationships and other business disruptions for ourselves and Asco as a result of the acquisition; 33) our ability to continue selling certain receivables through our supplier financing program; 34) the risks of doing business internationally, including fluctuations in foreign current exchange rates, impositions of tariffs or embargoes, compliance with foreign laws, and domestic and foreign government policies; and 35) our ability to complete the proposed accelerated stock repurchase plan, among other things.

Brent Taylor, Beyond Meat's VP of Corporate Development believes the firm's ability to focus on its core competencies has enabled it to grow rapidly without getting bogged down in such necessary time sucks as payroll, benefits and vacation time.

«As interest rates begin to rise over time, financial institutions will find it necessary to pass along their increased costs in the overall cost of credit to small business and commercial customers.»

Factors which could cause actual results to differ materially from these forward - looking statements include such factors as the Company's ability to accomplish its business initiatives, obtain regulatory approval and protect its intellectual property; significant fluctuations in marketing expenses and ability to achieve or grow revenue, or recognize net income, from the sale of its products and services, as well as the introduction of competing products, or management's ability to attract and maintain qualified personnel necessary for the development and commercialization of its planned products, and other information that may be detailed from time to time in the Company's filings with the United States Securities and Exchange Commission.

«For the record, we wish to make it clear that as we start this trial David Baazov and his counsel have not been given by the AMF or this court the time necessary to review the millions of documents disclosed and judged potentially relevant,» she said.

It's deep stuff, and it doesn't mean that you have to dwell on this all the time as you're trying to do what you have to do to succeed: Identify important customer needs, create solutions, develop a compelling value proposition, gather necessary resources, build credibility, and lead your venture to greatness.

The greatest basketball player of all time along with many other great leaders of our time only became great because they accepted setbacks as necessary steps along the journey.

«So we suggest that in all cases, if they're minor children, a trust structure is used to hold the assets and allot them to the children as the client and we recommend is necessary over time.»

Training full time, sacrificing studies and jobs, can have huge opportunity costs as well, as missing out on necessary education and prime years of work experience take tolls on later earnings.

It's abundantly clear that, as the speed of our days increases, we're losing the one - on - one time necessary to connect with the people in our lives and in our companies whose thoughtful input we need to make smart decisions and right choices for the future.

Science and engineering are necessary, but when it comes time to lead, use what works, such as empathy, field work, compassion, meeting people where they are, and living consistently by your values, with integrity.

Only collect information that is absolutely necessary as the user will likely give up if it is too time consuming.

The men were told to look at the images for as long as necessary to make their judgments, and longer time spent looking specifically at the faces and bodies of the gay male couples was taken by the researchers as another sign of attraction to men.

The ECB added at the time that it would adapt its policy as necessary depending on the trajectory of inflation.

In other words, the most successful entrepreneurs put no time or energy into stressing about their failures as they see failure as a small and necessary step in the process of reaching their goals.

When you have been around the block a few times in sales or as a business owner, you understand the mental strength necessary to cope with rejection.

For now, the best response is that a program such as the above — applied when necessary beyond Iraq, Syria, and ISIS to other challenges against the international order — would buy the Middle East time for the modernization and internal transformation needed to anchor the nation - state principle and provide homegrown disincentives to violence and upheaval.

At my company, Retention Science, I ask team members to submit their dates for time off, but only so managers can redistribute tasks as necessary before each person leaves.

«I follow up as many times as necessary until I get a response,» Steli explains.

China's official mouthpiece, Global Times, contended in an editorial: «If the Western countries accept India as a nuclear country and are indifferent to the nuclear race between India and Pakistan, China will not stand out and stick rigidly to those nuclear rules as necessary.

It should include specific tasks to be accomplished — say, for a Web developer, creating a fully functional and easily navigable site, including sales mechanisms and search - engine optimization, as well as educating employees on how to keep up the site if necessary — and under what time frame.

As with any workplace technology, over time it's necessary to identify areas where functionality could be enhanced — either via internal resources or with the help of the IWMS vendor.

The goal of TRX is to find like minded individuals who don't have the time, the credit, or the start up costs that are necessary in acquiring an income producing property on there own, but wishes to reap the benefits as part of a group who does.

Executive sessions of independent directors are held in connection with each regularly scheduled Board of Directors meeting and at other times as necessary, and are chaired by the Chairman of the Board of Directors.

Executive sessions of independent directors are held in connection with each regularly scheduled board of directors meeting and at other times as necessary, and are chaired by the Lead Independent Director.

Our independent directors regularly meet in executive session, and at such other times as necessary or appropriate as determined by the independent directors.

As industry competition intensifies, hospitality businesses struggle to make time for comprehensive training initiatives that are necessary for a highly - personalized guest experience.

By creating an account, you agree to (a) provide accurate, current and complete account information, (b) maintain and promptly update from time to time as necessary your account information, (c) maintain the security of your password and accept all risks of unauthorized access to your account and the information you provide to us, and (d) immediately notify us if you discover or otherwise suspect any security breaches related to the Sites or your account.

Dealerships that sell a wide variety of brands, mostly gas - powered, would have little incentive to take the time necessary to sell something as unusual as a Tesla, said James Chen, vice president of regulatory affairs for Tesla.

Unless your organization functions on rigid time structures — such as medical facilities, service industries, etc where service and success is dependent on having enough staff in the right places at the exact right times to service customers — then having «core hours» or expecting employees to work insane overtime is really not necessary — who cares as long as the work gets done and the customer is happy!

Two income households are becoming increasingly necessary at the same time as single - parent households are on the rise.

The Board may, from time to time, establish or maintain additional committees as the Board deems necessary or appropriate.

Therefore, if you do not have the passion and commitment necessary for this business, it is best not to waste your energy, time and resources especially as this is a business that will require you to be proactive.

Specifically, Defendants made false and / or misleading statements and / or failed to disclose that: (i) the Company was engaged in predatory lending practices that saddled subprime borrowers and / or those with poor or limited credit histories with high - interest rate debt that they could not repay; (ii) many of the Company's customers were using Qudian - provided loans to repay their existing loans, thereby inflating the Company's revenues and active borrower numbers and increasing the likelihood of defaults; (iii) the Company was providing online loans to college students despite a governmental ban on the practice; (iv) the Company was engaged overly aggressive and improper collection practices; (v) the Company had understated the number of its non-performing loans in the Registration Statement and Prospectus; (vi) because of the Company's improper lending, underwriting and collection practices it was subject to a heightened risk of adverse actions by Chinese regulators; (vii) the Company's largest sales platform and strategic partner, Alipay, and Ant Financial, could unilaterally cap the APR for loans provided by Qudian; (viii) the Company had failed to implement necessary safeguards to protect customer data; (ix) data for nearly one million Company customers had been leaked for sale to the black market, including names, addresses, phone numbers, loan information, accounts and, in some cases, passwords to CHIS, the state - backed higher - education qualification verification institution in China, subjecting the Company to undisclosed risks of penalties and financial and reputational harm; and (x) as a result of the foregoing, Qudian's public statements were materially false and misleading at all relevant times.

The memo also demonstrated his willingness to rankle Times management, even though it was ultimately seen as necessary.

While some respondents said they would be willing to exchange certain benefits to have work flexibility, such as vacation time or 401K contributions, 43 % said that should not be necessary.

When setting up any account on the blockchain, please take your time and take all necessary steps as a precaution.

That said, the move in the past several days that lifted yields on 10 - year Treasury notes to a five - month high was absolutely necessary, as a story this week in the Financial Times so aptly put it.

Whether you are a first - time homebuyer or on to make your repeat purchase, it is necessary to learn as much as you can about the Philippine real estate buying process.

A daily close over 2104.75 is necessary to project back to new all - time highs for S&P 500 futures as well as the S&P 500 Index (INDEXSP:.

For some websites, a time - consuming manual link building campaign is a necessary evil as the industry within which the site operates is very competitive from an SEO standpoint.

As you round the bend toward retirement, it's not a good idea to take on any more investment risk than necessary for your time frame, financial circumstances, and risk tolerance.

At these times, you may be able to get a temporary working capital line of credit, which allows you to draw on the credit line as necessary to meet cash flow shortages.

Examples of these risks, uncertainties and other factors include, but are not limited to the impact of: adverse general economic and related factors, such as fluctuating or increasing levels of unemployment, underemployment and the volatility of fuel prices, declines in the securities and real estate markets, and perceptions of these conditions that decrease the level of disposable income of consumers or consumer confidence; adverse events impacting the security of travel, such as terrorist acts, armed conflict and threats thereof, acts of piracy, and other international events; the risks and increased costs associated with operating internationally; our expansion into and investments in new markets; breaches in data security or other disturbances to our information technology and other networks; the spread of epidemics and viral outbreaks; adverse incidents involving cruise ships; changes in fuel prices and / or other cruise operating costs; any impairment of our tradenames or goodwill; our hedging strategies; our inability to obtain adequate insurance coverage; our substantial indebtedness, including the ability to raise additional capital to fund our operations, and to generate the necessary amount of cash to service our existing debt; restrictions in the agreements governing our indebtedness that limit our flexibility in operating our business; the significant portion of our assets pledged as collateral under our existing debt agreements and the ability of our creditors to accelerate the repayment of our indebtedness; volatility and disruptions in the global credit and financial markets, which may adversely affect our ability to borrow and could increase our counterparty credit risks, including those under our credit facilities, derivatives, contingent obligations, insurance contracts and new ship progress payment guarantees; fluctuations in foreign currency exchange rates; overcapacity in key markets or globally; our inability to recruit or retain qualified personnel or the loss of key personnel; future changes relating to how external distribution channels sell and market our cruises; our reliance on third parties to provide hotel management services to certain ships and certain other services; delays in our shipbuilding program and ship repairs, maintenance and refurbishments; future increases in the price of, or major changes or reduction in, commercial airline services; seasonal variations in passenger fare rates and occupancy levels at different times of the year; our ability to keep pace with developments in technology; amendments to our collective bargaining agreements for crew members and other employee relation issues; the continued availability of attractive port destinations; pending or threatened litigation, investigations and enforcement actions; changes involving the tax and environmental regulatory regimes in which we operate; and other factors set forth under «Risk Factors» in our most recently filed Annual Report on Form 10 - K and subsequent filings by the Company with the Securities and Exchange Commission.

The Trustee will, when directed by the Sponsor, and, in the absence of such direction, may, in its own discretion, sell such Bitcoins at such times as may be necessary to permit payment in cash of Trust expenses not assumed by the Sponsor.

Sophisticates may smirk at the great expectations of the Victorians - and there was no shortage of smirking sophisticates at the time - but the Victorians understood, as most in our culture do not, that there is a necessary connection between being good and pretending to be good.

The passage of time provides the «frame» necessary to discern those patterns — but only if the events themselves are faithfully recorded, «plotted» as on a graph.

The fossil record which shows millions of years of stable species, then an explosion of necessarily mutations, all occurring at the precise necessary time required for complex organisms to develop, and ALL escaping fossilization «the sudden appearance of most species in the geologic record and the lack of evidence of substantial gradual change in most species — from their initial appearance until their extinction — has long been noted, including by Charles Darwin who appealed to the imperfection of the record as the favored explanation» — Wikipedia

Persecution and mocking is as necessary now as in Jesus times.