Sentences with phrase «as tumor suppressors until»
In cancer research, the CBP and p300 proteins were known as tumor suppressors until the Panne lab showed that several known cancer mutations could cause p300 to over-activate itself.
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«Several studies and clinical evidence suggest AIM2 functions as a tumor suppressor, but until now, we've had very little direct evidence to explains how this occurs,» said Justin E. Wilson, PhD, the study's first author and a postdoctoral fellow at UNC Lineberger, the UNC School of Medicine Department of Microbiology and Immunology and the Department of Genetics.