Sentences with phrase «as tumors form»

The memory and thinking problems experienced by cancer survivors, known as «chemo brain» or «chemo fog,» are not just the result of chemotherapy treatment, they may start as tumors form and develop, suggests a Baycrest - led study.

Not exact matches

Cancer cells and tumors at first rely on nearby blood vessels to get what they need to survive, but, as tumors grow, they need to form new vessels.

That light is absorbed by the chlorine - based molecules, which then excite nearby oxygen molecules, creating a highly reactive form of oxygen, known as singlet oxygen, that rips apart nearby biomolecules and kills the tumor cell.

This causes genomic instability in developing immune cells and, in the absence of a working tumor suppressor protein such as p53, an aggressive form of lymphoma develops in mice.

This allowed them to map a «family tree» of the changes happening at a genetic level as the disease spreads, forms new tumors, and becomes resistant to treatment.

The study's findings, published in the journal Cancer Research, are the first to use these combined agents as an immune stimulator and may have the potential to kill cancerous cells in solid tumors, including some of the most aggressive cancers that form in the lung and pancreas.

But as malignant cells multiply and form tumors, they release biochemical signals that suppress the immune system and the T - cells no longer function properly.

Record mice with tumors that are large and form close to the neck as these may give metastasis more efficiently.

In the replicators» hands, however, cancer cells with and without the PREX2 mutations both formed tumors within a week — not weeks as originally reported — making it impossible to tell whether PREX2 made any difference.

At a time when gene therapy has been revived as a potent form of cancer treatment, a new approach would use nanoparticles, rather than viruses, to deliver strands of DNA or RNA to tumors.

Thus, in a panel of breast cancer samples, we identified tumor cells that did not form part of the bulk tumor mass, but instead were interspersed within the adjacent stroma — as if forming the forefront of cancer cell invasion.

Proton therapy is an advanced form of radiation treatment that is especially effective for reaching tumors or remaining cancer cells close to key organs such as the brain stem or spinal cord.

«Our work supports the idea of exploring the use of Onyx - 015 in tumors that we presumed would be immune to the drug because they were thought to frequently have p53 genes, such as such as melanoma and glioblastoma [a form of brain cancer].

But scientists are now learning that cancer cells also make use of such regulatory cells, sometimes strategically luring them to the site of a tumor as a form of defense.

Doctors are already using drugs, such as Herceptin, that specifically target malfunctioning genetic pathways in tumors, but no such therapies are currently available for certain aggressive forms of the disease, such as the triple negative subtype.

CFE was calculated by dividing the number of tumor spheres formed by the original number of single cells seeded and is expressed as a percentage.

Blastoma: Tumors formed from embryonic tissue or developing cells are known as blastomas and are more common in children than adults.

According to recent research, the most common solid tumors (that is, cancer that occurs as clusters of cells in or on organs, rather than in liquid form within the blood or lymphatic system) have up to 66 mutations that influence how the cancer cells operate — how fast they divide, whether they are susceptible to the signals that would normally cause a cell to die, when they detach from the main tumor to colonize another organ in the body, when and where they attach blood vessels to healthy tissues.

The knowledge about how this cancer form arises and develops is still limited but new results from a research team led by Lene Uhrbom, Uppsala University / SciLifeLab, shows that disease progress and the malignancy are affected by the cell type from which the tumor originates as well as the age of the patient.

The tumors formed in mice co-treated with chidamide and decitabine were significantly smaller than those that formed in untreated animals or those treated with the single agents, starting from 15 days of treatment (Figure 4C, left panel), as visualized by 18F - fluorodeoxyglucose small - animal positron emission tomography — computed tomography at 21 days of treatment (Figure 4C, right panel).

As a tumor immunologist at UCLA's Jonsson Comprehensive Cancer Center, Dr. Ribas specializes in the research and treatment of melanoma, the deadliest form of skin cancer.

Neoantigens — called so because they are newly formed during cancer development — may represent ideal immunotherapy targets as they are solely expressed on tumor cells.

PNNL scientists will use proteomics instruments developed at EMSL, a Department of Energy national scientific user facility at PNNL, to study the expressed proteins and their modified forms in tumors that have been analyzed as part of the NCI's Cancer Genome Atlas.

I had a hunch based on this work that microRNA expression would be different in breast cancer stem cells than in more differentiated tumor cells or normal tissue and that it would change as the stem cells differentiated to form a tumor.

Researchers led by St. Jude Children's Research Hospital scientists have worked out how a crucial cancer - related protein, a «histone writer» called Ezh2, plays a role in suppressing as well as driving the most aggressive form of the brain tumor medulloblastoma.

For example, proteins related to angiogenesis, the process through which new blood vessels form to ensure supply of oxygen and nutrients to a tissue such as a tumor, are found to be clearly associated to clinical outcome in HPV - positive samples.

Many women are «triple negative» No one yet knows precisely why, but African - American women are roughly twice as likely as white women to have triple - negative breast cancer — so called because tumor cells in this particularly aggressive form of the disease test negative for estrogen receptor (ER), progesterone receptor (PR), and human epidermal growth factor receptor 2 (HER - 2).

The chronically stressed mice had decreased immune function and experienced tumor development significantly earlier than the non-stressed mice.16 Other mouse studies of ovarian cancer showed that chronic stress resulted in increased cancer growth as well as increased angiogenesis, the process with which cancer forms new blood vessels to feed itself nutrients for growth and metastases.17 Chronic stress has also been shown to decrease our body's ability to mount an attack against foreign invaders, including viruses.18 As we know that several viruses can cause cancer (HPV and cervical cancer, and EBV and nasopharyngeal cancer), we can extrapolate that any decrease in immune function could increase cancer risas well as increased angiogenesis, the process with which cancer forms new blood vessels to feed itself nutrients for growth and metastases.17 Chronic stress has also been shown to decrease our body's ability to mount an attack against foreign invaders, including viruses.18 As we know that several viruses can cause cancer (HPV and cervical cancer, and EBV and nasopharyngeal cancer), we can extrapolate that any decrease in immune function could increase cancer risas increased angiogenesis, the process with which cancer forms new blood vessels to feed itself nutrients for growth and metastases.17 Chronic stress has also been shown to decrease our body's ability to mount an attack against foreign invaders, including viruses.18 As we know that several viruses can cause cancer (HPV and cervical cancer, and EBV and nasopharyngeal cancer), we can extrapolate that any decrease in immune function could increase cancer risAs we know that several viruses can cause cancer (HPV and cervical cancer, and EBV and nasopharyngeal cancer), we can extrapolate that any decrease in immune function could increase cancer risk.

Antioxidants are important for fighting cancer as they fight free radicals before they can mutate a cell's DNA to form cancer cells and, subsequently, tumors.

Increased levels of circulating IGF - 1 as adults can promote unwanted growth, particularly in the form of tumors.

As more cancer cells develop, they form a tumor.

If true, then the use of this medicinal mushroom as an adjunct or preventative therapy may help many patients better fight the battle when challenged with tumor - forming cancers.»

And, although this effect may help to prevent heart attacks and other forms of heart disease, it may have the potential to promote cancer as well by increasing the growth of blood vessels in cancerous tumors.

«Besides affecting tumor cells» directly, phytates «can act on [our] immune functions» by augmenting natural killer cell activity, the cells in our body that hunt down and dispose of cancer cells, as well as neutrophils, which help form our «first line of defense.»

Cancer shortens the lives of nearly half of all dogs and cats in the U.S. Cancer in pets occurs when the body's immune system can not stop cells from replicating at an abnormally fast, disorderly pace and forming a mass known as a tumor.

Too many vets are still vaccinating in the scruff of the neck - which has been strongly recommended against since the mid-1990s, since tumors that form there are inoperable; whereas a leg can be amputated when cancer invades there, as long as the vaccines are injected far enough away from the body.

In one study of 41 dogs with either primary or secondary brain tumors, all dogs received some form of definitive treatment (such as surgery, megavoltage radiation, chemotherapy, etc).

The very rare, multiple, malignant form of pilomatricoma may spread throughout the body, often very rapidly and before the primary tumor is noted as a significant problem.

Blood turbulence after the RBCs are formed (as in hemangiosarcoma tumors or certain heart diseases) have also been associated with poikilocytosis.

A careful balance exists where there are the same number of new cells are produced as there are dying off - and if this balance is disrupted, extra cells begin to replicate, undergo genetic changes, and it is these excess, mutated cells that gather together to form masses and tumors.

Ultrasound does not require any form of sedation, and can quickly help our veterinarians identify and locate issues such as tumors, cysts, stones, and inflammation.

Lypomas are fatty deposits, sometimes described as tumors, which form just under the skin.

As these cells multiply unchecked, they form tumors.

«Dog lumps on skin (also called dog skin tumors) can have many causes such as an insect bite that results in an abscess where pus forms under the skin, lipomas (fatty tumors which are usually benign or not cancerous), skin tumors or cysts.

For dogs and cats, the most common form of tumor in the brain is known as a meningioma.

Large and small animal nuclear medicine is available and is a subspecialty of radiology in which radioisotopes (compounds containing radioactive forms of atoms) are put into the body to evaluate organ function or localize bone disease such as stress fractures or tumor metastasis.

As the tumor grows, abnormally fragile blood vessels are formed, which have the tendency to break open and bleed.

Mast cell tumors, as with many other forms of cancer, tend to be associated with age.

Bacteria, viruses and other microbes can cause a primary form of canine eye infection, but in many cases, it is possible that eye infections may occur as a secondary problem, which means it is a result of another condition such as glaucoma, atrophy (muscle weakness0, ulcers, dog Cherry eye, tumors and a parasitic infestation (mange, flea infestation) over the face.

Ni had a very aggressive form of cancer known as squamous cell carcinoma and the tumor cells extended all the way to the margins.