Sentences with phrase «as tumors grow»

This is because as these tumors grow, they start to press on different areas of the brain.

Cancer cells and tumors at first rely on nearby blood vessels to get what they need to survive, but, as tumors grow, they need to form new vessels.

As tumors grow and develop, they shed micro-metastases, clusters of a few cells that take up residence in far - flung organs such as the brain, liver and bone.

The accumulation of new mutations as a tumor grows and metastasizes also complicates matters.

As a tumor grows, symptoms may include blood in the urine, pain or a lump in the lower back or abdomen, fatigue, weight loss, and swelling in the ankles or legs.

As the tumor grows and the lactate builds up, a metabolic condition similar to Type II diabetes ensues.

As the tumor grows, seizures can occur.

When they do, the symptoms that we see are due to the physical destruction of these organs as the tumor grows and crowds out healthy cells.

Over time, the dog's face might become distorted as the tumor grows.

As the tumor grows, abnormally fragile blood vessels are formed, which have the tendency to break open and bleed.

Not exact matches

It's as if the Earth now has two moons instead of one and both are growing in size like a cancerous tumor that may threaten the financial tides, oceans and economic life as we have known it for the past half century.

At a time when individual tribulations seem to have grown with increasingly difficult economic times, it's no wonder that the ballroom was filled with at least 200 people from as far as New York, New Jersey and Virginia, many with testimonies of being cured of ailments from chronic sinus issues and financial woes, to smoking cessation and the disappearance of tumors.

Have I seen what I could call a bona fide miracle (such as a leg grow or a tumor disappear..

As the pregnancy continued, the tumor grew.

X-rays also pick up white specks of calcium deposits that may be generated by a tumor as it grows.

Several studies have supported a role for cancer stem cells in the aggressive brain tumors called glioblastoma, but those studies involved inducing human tumors to grow in mice, and as such their relevance to cancer in humans has been questioned.

A glioblastoma tumor requires large amounts of energy as it grows, and the dietary intervention works by drastically limiting the tumor's supply of glucose, Reynolds said.

These modifications contribute to a tumor's ability to grow indefinitely, as well as making tumor cells drug resistant and capable of surviving treatments intended to kill them.

A fast - growing tumor (solid red) displaces nerve fibers (colored strands) in a false - color image of a 54 - year - old woman's brain, as seen from above.

Researchers said the importance of collecting tissue samples from recurrent tumors will grow as more targeted therapies become available.

But as noted in a recent Science news story, targeted therapies don't work as well on solid tumors, which usually develop resistance and start growing again.

Following cancer therapy, the dominant cells may die first, and other cells that were originally not as fit may find themselves better able to compete for necessary space and nutrients and continue to grow and take over the tumor.

As proof - of - principle of the potential efficacy, Zhang's team grew human ovarian tumors in immunocompromised mice, then injected short - interfering RNAs to block the tumors» growth using RNA interference against FAL1.

This may allow surgeons to look at the perimeter of a growing tumor and use the shape to guide their assessment of which regions could be more problematic — where they need to take out more tissue around the tumor and where they may not need to take as much.»

In some cases such as ovarian cancer, however, drug - free intervals are needed to allow patient recovery from side effects, during which tumors can sometimes begin to grow again or develop resistance to the drugs being used.

Block or remove the estrogen with different types of drugs, such as the commonly prescribed tamoxifen or aromatase inhibitors, and the tumor stops growing.

As such, their tumors grow more quickly.

Experimental and unregulated stem cell therapies have resulted in brain tumors, for example, as well as bones growing in eyelids.

As pancreatic tumors grow and evolve, they collect LINE - 1 insertions, Burns and colleagues reported in Nature Medicine in 2015.

In stage T4a larynx cancer the tumor grows through the thyroid cartilage and / or into tissues beyond the larynx, such as the thyroid gland, trachea, esophagus, tongue muscles, or neck muscles.

Because diseases such as cancer tend to evade detection by T - cells» receptors, allowing a tumor to grow unchecked, scientists have long sought «intel» on this process as a means of developing therapies that target malignant cells, but leave healthy cells alone.

As an additional safety feature, the researchers introduced two mutations that weakened the virus's ability to combat the cell's defenses against infection, reasoning that the mutated virus still would be able to grow in tumor cells — which have a poor antiviral defense system — but would be eliminated quickly in healthy cells with a robust antiviral response.

The researchers grafted breast or lung tumors in mice, allowed the tumors to grow to small size and removed these tumors surgically — essentially mimicking the situation in a human tumor patient in which the tumor is surgically removed as soon as possible after diagnosis.

These proteins, such as endostatin, inhibit the growth of blood vessels that the tumors need to grow and spread (ScienceNOW, 23 January 1997).

«Information and data is moved in real time to Deep Computing Visualization and can be used to view a tumor as it's growing — or hopefully not growing — because some other agents have been injected into the tumor,» Dodd said.

As evidenced by CT scan, the cancer did not grow or spread in all 31 patients who completed chemotherapy, thus all patients received three SABR treatments of 36 Gy each, including a 2 mm expansion around the gross tumor.

When such DNA damage occurs, proteins known as PARPs move to the site of damage and begin to mend these broken strands of DNA, allowing cancerous cells and tumors to recover, grow and proliferate, thereby escaping the effects of treatment.

These extraordinary effects suggested that the overgrowth of the sympathetic ganglia was more than simply a response to the rapidly growing peripheral field of innervation provided by the tumor, as Bueker had proposed.

NCI's efforts to develop new laboratory models of human cancer includes vastly increasing the number of human cancer cell lines (grown as two - dimensional and three - dimensional cultures) and patient - derived tumor xenografts.

The Joslin team found that intestinal tumors grow just as quickly in a mouse cancer model whose «epithelial» cells lining the inside of the intestine have been genetically modified so that insulin can't activate the cells.

Instead of talking about cures and remission, doctors are now talking about cancer as being more of a controlled equilibrium with a tumor, in which it does not grow or cause issues.

To answer basic research questions like these, investigators study bacteria, viruses, fungi, animal cells and human cells (both healthy and cancerous) grown in the lab, and tumors in animals, such as mice and rats.

They changed the way we think about many types of malignancy and provided new and effective ways to treat and prevent many hormone - driven tumors, a tradition that has expanded as the department has grown over the years.

A clear and growing body of evidence supports the notion that epigenetic alterations, such as DNA methylation, occur early in and contribute to tumor formation.

In parallel, Georgetown Lombardi's Stephen Byers, PhD, will grow the patient tumors in a novel «avatar» — zebrafish, to be used as a surrogate to predict response and determine resistance pathways.

It's called molecular - targeted therapy and it works as advertised: The drugs do disable the molecules that drive growth — but, again, tumors figure out a new way to grow.

As brain tumors grow, they can cause a wide array of challenging symptoms for patients due to pressure in the brain and / or interference with normal brain function.

Moreover, the ever - growing catalogues of tumor genome sequences — such as those created by the Cancer Genome Atlas (TCGA) and the International Cancer Genome Consortium (ICGC)-- enable integrated analyses of germline variation with somatic mutation data across tumor types (i.e. pan-cancer analysis).

In this study, human lung cancer cells with additional copies of the opioid receptor grew more than twice as fast as tumor cells that lacked extra receptors when transplanted into mice.

Genetic mutations that alter tumor suppressors such as the p53 gene are known to help tumors grow, and epigenetic modifications, too, can deactivate genes like this one.