Sentences with phrase «as tumors of»

Vaginal and preputial discharge of any character as well as tumors of the reproductive tract are often found in spayed and neutered animals.

This same feature, tumor heterogeneity, may reduce the ability to identify critical gene expression changes when comparing mean gene expression in adjacent tumor and normal tissues, as tumors of the same type may have different sets of genes differentially expressed.

Not exact matches

Others have found that bacteria within the tumors themselves can influence the effectiveness of traditional chemotherapy as well.

Immunotherapy differs from more traditional cancer treatments, such as surgery (cutting malignant cells out of the body), chemotherapy and radiation (poisoning the deadly mutants), and even the newer, more precise molecular drugs that attempt to jam the protein signals that tell tumor cells to keep dividing and conquering.

It will focus its initial clinical sequencing efforts on cancer, teaming up with the Moores Cancer Center at the University of California, San Diego to sequence the genomes of every patient who is treated there, as well as perform a full genome sequence on their tumors.

But none of the control rats developed brain tumors as would have been expected, and the male rats exposed to radiation actually outlived their non-exposed counterparts.

(There are some exceptions to the rule, as certain tumor viruses demonstrate — see the sad, heroic tale of Nobel laureate Howard Martin Temin, who had the effrontery to challenge said dogma.)

The Kamens claim the main thing that distinguishes their foundation from other brain tumor foundations is their focus on pediatric brain cancer specifically, as well as their close ties with pharmaceutical and biotech companies working in the fields of immunotherapy and target gene therapy.

It's as if the Earth now has two moons instead of one and both are growing in size like a cancerous tumor that may threaten the financial tides, oceans and economic life as we have known it for the past half century.

Dr. Robert Marx, chief of oral and maxillofacial surgery for the University of Miami Health System, at a press conference discussing the removal of a 10 - pound tumor on the face of Emanuel Zayas, 14, as his parents Melvis Vizaino and Noel Zayas lis

The partnership will seek approval for a version of the Illumina's test, TruSight Tumor 170, as a companion diagnostic for Loxo's larotrectinib and another one of Loxo's experimental cancer drugs, across tumor tTumor 170, as a companion diagnostic for Loxo's larotrectinib and another one of Loxo's experimental cancer drugs, across tumor ttumor types.

As a cancer researcher, do you think the mechanisms of tumor growth are somehow changing to come into line with your perceptions, or is it possible that the process of our learning more about DNA mutations and cell architecture and nutrient exchange and epigenetic effects make it possible for us to inch ever closer to understanding that which is already going on under our noses?

At a time when individual tribulations seem to have grown with increasingly difficult economic times, it's no wonder that the ballroom was filled with at least 200 people from as far as New York, New Jersey and Virginia, many with testimonies of being cured of ailments from chronic sinus issues and financial woes, to smoking cessation and the disappearance of tumors.

Two other reports in the same issue of Cancer Causes and Control suggest that children born to mothers who eat at least one hot dog per week during pregnancy have double the normal risk of developing brain tumors, as do children whose fathers ate hot dogs before conception.

In an article posted on MD Anderson's blog, professor in the Department of Experimental Therapeutics, Dr. Bharat Aggarwal, Ph.D., points out that, «Symptoms common in cancer patients, such as depression, fatigue, neuropathic pain, metastases and tumor growth, are due to inflammation.

Similar to capsaicin, tumor necrosis factor is suspected to both induce and reduce cancer cell growth, and was shown to commit cells to survival when stimulating EGFR transactivation mechanisms, indicating that EGFR could act as a molecular switch determining the antiapoptotic effect of tumor necrosis factor (50).

Both TRPV1 / WT and KO mice treated with capsaicin and TPA together exhibited higher COX - 2 protein levels than groups treated with TPA alone (Fig. 2A), and tumors from TRPV1 / KO mice expressed the highest level of COX - 2 as a result of treatment with capsaicin and TPA together (Fig. 2A).

Prince Philip has been going around with a bandaged right wrist as a result of having had a cyst removed, a tumor that one London surgeon said was possibly a consequence of the Prince's polo playing.

Bad news for all Barcelona fans as Tito Vilanova is set to step down as the first team coach after suffering a relapse of a tumor he had removed last year.

The story is an allegory for the death of Pirola's own father, John, who suffered for years through searing neuropathic pain as a result of a brain stem tumor, and over several years, underwent more than 10 brain / skull - based surgeries.

After John's diagnosis, when Isabella was in third grade, the family relocated from North Carolina to Michigan, then later, on to New York and Minnesota as John underwent surgeries to remove tumors, implant pain pumps and reconstruct parts of his skull.

You can feel good about owning a Happy Napper ® too, as a portion of their sales is donated to the Home Sweet Home Fund, benefitting The Children's Brain Tumor Foundation.

They are believed to be behind hormonal imbalances as some of it is normally found in tumors.

Because Kraft, Coca Cola and Wal - mart are living proof that is possible for giant corporations to make and sell kid - friendly, family - friendly, and healthy processed foods so that we can give our kids some special treats — like the U.K. versions of Starburst and Skittles, for example — without necessarily exposing them to a chemical cocktail that might also give them brain tumors, or leukemia, or the symptoms of ADHD, as the Center for Science in the Public Interest recently highlighted in their report «Rainbow of Risks».

Therefore, the sudden onset of a mental disorder is a red flag for biological abnormalities such as vascular disease, strokes, nutritional deficits, infections, hormone irregularities, tumors, or exposure to toxins.

«We also confirmed a role in PDAC tumor maintenance as inhibition of PRMT1 in patient - derived mouse models significantly inhibited tumor growth and extended survival,» said Giuliani.

Researchers at NYU School of Medicine found that the value of the drug infliximab, marketed as Remicade, in both applications proceeds from its ability to block the contribution of the protein tumor - necrosis factor alpha, or TNF alpha, to problem - causing inflammation.

After adjusting for age, tumor location, and stage, researchers from Cleveland Clinic's Dermatology & Plastic Surgery Institute discovered that women diagnosed with malignant melanoma during their pregnancy or within one year of giving birth were 5.1 - times as likely to die, 6.9 - times as likely to experience metastasis, and 9.2 - times more likely to have a recurrence.

However, the impact of the two methylation - regulating enzymes was still seen at 10 to 15 months, when scientists found decreased expression of hundreds of genes — many of which are key tumor suppressor genes such as BMP3, SFRP2 and GATA4 — in the smoke - exposed cells and a five - or - more-fold increase in the signaling of the KRAS oncogene that is known to be mutated in smoking - related lung cancers.

Gene therapy procedures in humans have been linked to the onset of leukemia and various tumors, as well as sudden death.

«Through this assessment of epigenetic regulators, we identified PRMT1 as a top scoring «hit» in these patient - derived tumors,» said Virginia Giuliani, Ph.D., senior research scientist, IACS.

«Once this novel tumor - homing agent binds to the EphA2 receptor, the oncogene functions as a cancer - specific molecular Trojan horse for paclitaxel, carrying the drug inside the cancel cell, killing the cell, and thwarting metastasis,» said Maurizio Pellecchia, a professor of biomedical sciences at UCR's School of Medicine who led the research.

The focus of those hopes is the liquid biopsy: a test that could detect and analyze a solid tumor from biomarkers in the bloodstream or other easily sampled body fluids, such as saliva.

«Nonetheless, the proof of concept studies we have obtained thus far are extremely encouraging, and we are confident that with proper support and efforts we could translate our findings into experimental therapeutics for a variety of solid tumors that are driven by EphA2 overexpression, including breast, lung, prostate, pancreatic, and ovarian cancers,» said Pellecchia, who serves as the founding director of the Center for Molecular and Translational Medicine at UCR.

Teixeira and his team also found that a malfunctioning tumor - suppressing gene that's associated with certain cancers, such as colon and pancreatic, and is known as Stk11, additionally influenced the development of BPH.

As researchers learn more about genetic profile of various cancers, other work is charging ahead to deliver personalized vaccines targeted to a patient's own tumor cells

Abnormal resistance in the abdomen, for example, can point to the presence of tumors as well as enlarged organs.

«The minimum sample volume required is only 1 µL for analysis of 92 proteins, which has been proven to be a great advantage for applications with limited sample volumes, such as pediatric applications, fine - needle biopsies, and tumor microbiopsies,» he says.

Recently, DNA shed from tumor cells has been identified as a noninvasive method of screening biomarkers for the early diagnosis and prognosis of cancer.

As a result, «immune cells can go to all corners of the body and eradicate tumors,» Smith says.

But when their functioning is altered, as the UCL researchers observed in tumor cells, the mitochondria can promote cell migration, thus leading to the formation of metastasis.

Recent advances in the understanding of cancer have led to more personalized therapies, such as drugs that target particular proteins and tests that analyze gene expression patterns in tumors to predict a patient's response to therapy.

«What is particularly encouraging is that we are now able to select, based on features in the tumor, approximately a quarter of advanced lung cancer patients who can receive immunotherapy as their initial treatment.

Types 6 and 11 account for about 90 percent of genital warts as well as non-cancerous tumor growths in the respiratory tract.

According to Srikumar P. Chellappan, Ph.D., chair of the Department of Tumor Biology at Moffitt, «these cells can also contribute to the metastasis of tumors as well as the reappearance of tumors after they have been eliminated from the body.»

X-rays also pick up white specks of calcium deposits that may be generated by a tumor as it grows.

For some years now, a new class of drugs called antibody - drug conjugates (ADCs) have been used, which work in two ways: they consist of an antibody that binds selectively to the tumor cell receptor and interrupts the signal to propagate; they also act as a transport vehicle for a chemical substance that enters the cancer cells with the antibody and triggers their death.

Currently, rising blood levels of prostate - specific antigen (PSA), a protein made by the prostate gland, are used as indicators of tumor recurrence.

Inspired by his own bout of leukemia to try to find a better cancer treatment, retired broadcasting station owner Kanzius guessed that as an alternative to chemotherapy, he could inject tumors with metal ions, then use radio waves to heat the metal and destroy cancerous cells.

This is one of the first research studies to highlight the importance of the location of the metastasis as well as the location of the original primary tumor, in predicting response to radiation therapy.