Sentences with phrase «as uncertain risks»

So, instead of treating these continual processes as uncertain risks, engineers build in operations and maintenance procedures to track, minimize, replace, and correct material degradation problems before a disaster occurs.

Not exact matches

Actual results and the timing of events could differ materially from those anticipated in the forward - looking statements due to these risks and uncertainties as well as other factors, which include, without limitation: the uncertain timing of, and risks relating to, the executive search process; risks related to the potential failure of eptinezumab to demonstrate safety and efficacy in clinical testing; Alder's ability to conduct clinical trials and studies of eptinezumab sufficient to achieve a positive completion; the availability of data at the expected times; the clinical, therapeutic and commercial value of eptinezumab; risks and uncertainties related to regulatory application, review and approval processes and Alder's compliance with applicable legal and regulatory requirements; risks and uncertainties relating to the manufacture of eptinezumab; Alder's ability to obtain and protect intellectual property rights, and operate without infringing on the intellectual property rights of others; the uncertain timing and level of expenses associated with Alder's development and commercialization activities; the sufficiency of Alder's capital and other resources; market competition; changes in economic and business conditions; and other factors discussed under the caption «Risk Factors» in Alder's Annual Report on Form 10 - K for the fiscal year ended December 31, 2017, which was filed with the Securities and Exchange Commission (SEC) on February 26, 2018, and is available on the SEC's website at www.sec.gov.

So put such uncertain times to good use as a motivator to help ensure your investment strategy aligns with your long - term goals, timeline and stomach for risk.

The limitations of macroprudential policies reflect the potential for risks to emerge outside sectors subject to regulation, the potential for supervision and regulation to miss emerging risks, the uncertain efficacy of new macroprudential tools such as a countercyclical capital buffer, and the potential for such policy steps to be delayed or to lack public support.14 Given such limitations, adjustments in monetary policy may, at times, be needed to curb risks to financial stability.15

For years, Iran's nuclear programme has been regarded by most democratic countries as uncertain and seen by Israel, and later the United States, as a risk.

Until now, the risks of this exposure known as «third hand tobacco smoke» have been highly uncertain and not considered in public policy.

Wynne also suggests that risk is not only uncertain, but indeterminate, as are the social values embedded in risk assessment.

In brain imaging studies, the OPFC is highly active when people deliberate between actions with uncertain risks and rewards, and clinical reports describe patients, such as Gage, whose inability to consider long - term consequences can lead to tragic outcomes.

As a result, the balance between risks and benefits is still uncertain, says Gray, and it's ethical to keep enrolling women.

Conversely, having to provide customer support without the proper training demotivates employees, as they are uncertain how to handle certain support scenarios that occur (and thus nervous), and they risk appearing ignorant to the customer.

If it hadn't sold, I would have looked like a schmuck, but I'm with Jeremy, as long as a risk is carefully calculated, sometimes you have step outside your comfort zone, especially in these uncertain times.

Like the rest of us, they are seeking outcomes such as growth, income, reducing risk, and liquidity, amid an uncertain geopolitical, market and economic landscape.

Elite Access combines some of the most progressive investment strategies available today — as well as a disciplined methodology regarding the selection, review, and oversight of world - class money managers — to help you manage risk and stay invested during uncertain times.

So put such uncertain times to good use as a motivator to help ensure your investment strategy aligns with your long - term goals, timeline and stomach for risk.

We know the financial markets can be uncertain and full of risk, which is why we offer low risk IRA products such as CDs and savings accounts that offer more consistent returns and are FDIC - insured.

PR experts take advantage of poor Joe Public, misleading him with arguments such as science is uncertain, therefore the only risk to think of is risk of «huge disruption».

But in 2009, as I reported more and more on the inherent threat of climate extremes in some of the world's poorest places (sub-Saharan Africa, particularly) I became concerned that the uncertain impact of greenhouse - driven warming paled beside other drivers of risk (persistent poverty, doubling populations, and the existing pattern of super-drought).

If adapting to a projected climate shift cost less or even the same as prevention, adapting potentially minimizes the risk inherent in choosing actions based upon uncertain risk.

Proposed methods of extraction such as bioenergy with carbon capture and storage (BECCS) or air capture of CO2 imply minimal estimated costs of 104 - 570 trillion dollars this century, with large risks and uncertain feasibility.

That means that the basis of Mr. Gore's suggested «material - risk factor» — as distinct from an uncertainty — is itself uncertain.

Developing countries need help gaining access to capital as they are seen as riskier places to invest in, while clean energy is still regarded by many investors as a high - risk investment with uncertain returns.

Within the climate change context, risk can be defined as the potential for consequences where something of human value (including humans themselves) is at stake and where the outcome is uncertain.

Similar conclusions could also be applied to risks for social systems, though the literature often suggests that any thresholds for these are at least as uncertain.

Too Many Pipeline Failures With fracking, then, it is a choice of tangible profits over «uncertain» risks (although some of those risks are as «uncertain» as human - caused climate change).

It has become more important than ever for scientists, their allies, and public officials to speak out in no uncertain terms about the risks we face under a business as usual scenario.

From the point of view of this class — a class I'll just call «lawyers» — it's too clear for argument that (i) law has things to do so that some instrumentalist theory has to be adopted; (ii) few things are simple, so that no single theory will work in every case, whether it's «wealth maximization», «corrective justice», «contract as promise», compensation or deterrence; and (iii) the demands of practice, the solicitor's need to create relations which will be projected into the (uncertain) future and to control the risks his or her client faces, the barrister's need to conduct litigation at a price the parties can afford and in the context of the adversary system, powerfully limit the consideration that a lawyer can give to theory.

In an uncertain period, such as the one we're going through now, how does an investment magnate such as yourself weigh up the risks involved in particular transactions?

As Justice Green stated in McGill, at para. 31: ``... [T] here is a risk of injustice in relying on a sentencing model premised on judicially - created fixed ranges of imprisonment from which the sole reprieve is resort to an uncertain doctrine of exceptionality... The fairer and, in the end, more «principled approach» to the law of sentencing — as repeatedly mandated by the Supreme Court — is that of individualized proportionality.&raquAs Justice Green stated in McGill, at para. 31: ``... [T] here is a risk of injustice in relying on a sentencing model premised on judicially - created fixed ranges of imprisonment from which the sole reprieve is resort to an uncertain doctrine of exceptionality... The fairer and, in the end, more «principled approach» to the law of sentencing — as repeatedly mandated by the Supreme Court — is that of individualized proportionality.&raquas repeatedly mandated by the Supreme Court — is that of individualized proportionality.»

As a result I have developed a somewhat unorthodox approach to the subject that borrows heavily from the strategic management and risk management disciplines that are effectively employed by corporations and government to manage in uncertain times.

Corporate clients in the current buyers» market are increasingly demanding lower, fixed prices and value - based Alternative Fee Arrangements («AFAs») in lieu of hourly billing — making law firms bear the «risk of loss» in uncertain but complex litigation and transaction matters — even as the costs of running law firms continue to climb.

Because we understand our clients» technologies and business environment as well as the law, and because our judgment has been honed in novel litigation at the limits of copyright law, Fenwick & West is uniquely situated to advise on managing risks in an uncertain legal environment and on safeguarding intellectual property assets.

The time needed for such development is uncertain, and trial - and - error learning is required, as is accepting the risk of failure — the cost of learning is repeated failure.

My experience has given me wide experience of managing success and failures, uncertain risks as well as opportunities.

Multiple factors reportedly increase the risk of suicide.44 - 49 Substance abuse has repeatedly been associated with suicidal behaviors, and depression has as well.1,50 - 62 Moreover, previous reports from the ACE Study have demonstrated strong, graded relationships between the number of adverse childhood experiences and the risk of alcohol or illicit substance abuse and depressive disorders.23, 24,28 Although a temporal relationship between the onset of substance abuse or depressive disorders and lifetime suicide attempts in the ACE Study cohort is uncertain, our analysis of the potential mediating effects of these known risk factors provides evidence that for some persons, adverse childhood experiences play a role in the development of substance abuse or depression.

Definitional variation over time also means that we are uncertain as to how much of the change in the cumulative risk for confirmed maltreatment is due to actual changes in rates of maltreatment vs changes in definitions of maltreatment.

As summarized above, Wellens» testimony indicated that the cure was controversial, there is limited research data, and there are uncertain risks.