In this proteomic study, Jianyun Yu, Hu Zhou and colleagues
assessed brain protein levels after one or more concussions in rodents at multiple timepoints.
Not exact matches
Developing such biomarkers to
assess brain dysfunction will be a challenge, but in the same issue you draw attention to the excellent work of Abdul Hye and his colleagues who are developing a test to detect
protein biomarkers for Alzheimer's disease in blood (p 5).
In this study, we would like to further
assess the connection between sleep - wake states, aging, and
brain energy utilization and to determine how these factors influence Aβ as well as other
proteins relevant to AD and neurodegeneration.
Additional exploratory objectives include
assessing the impact that each compound has on the toxic mutant
protein known to cause loss of
brain cells in HD, as well as evaluating potential clinical effects and impact on
brain atrophy as measured by magnetic resonance imaging (MRI).
«Because of this finding, we propose that the body posture and sleep quality should be considered when standardizing future diagnostic imaging procedures to
assess CSF - ISF transport in humans and therefore the assessment of the clearance of damaging
brain proteins that may contribute to or cause
brain diseases.»