Previous studies have shown that men have an advantage in tasks
assessing visuospatial and mathematical abilities, whereas women are found to outperform men in tasks assessing episodic memory and reading literacy, with no differences normally observed in category fluency and vocabulary.
To test whether clinicoanatomic heterogeneity in AD is driven by the involvement of specific networks, network connectivity was
assessed in healthy subjects by seeding regions commonly and specifically atrophied in three clinical AD variants: early - onset AD (age at onset, < 65 y; memory and executive deficits), logopenic variant primary progressive aphasia (language deficits), and posterior cortical atrophy (
visuospatial deficits).