Sentences with phrase «associated cellular factor»

DDX3, also named as CAP - Rf (1) or DBX (2), is a hepatitis C virus core protein — associated cellular factor that belongs to the DEAD box RNA helicase family (1, 3, 4).

Not exact matches

«A general message from these studies is that cancer cells benefit from modulating epigenetic factors like SIRT6 by acquiring the ability to override normal cellular growth control patterns,» says Mostoslavsky, an associate professor of Medicine at Harvard Medical School and an associate member at the Broad Institute.

After grounding himself in math, molecular and cellular genetics, and immunology, he embarked on a 1 - year master's project at the University of the Mediterranean (which has now gone through a merger to become Aix - Marseille University), characterizing the genetic factors associated with malaria resistance under the supervision of Pascal Rihet.

This factor is required for Tat trans - activation and is a substrate of an associated cellular kinase.

Once the bacterial cell signaling protein cagA reaches the host cytosol, it is capable of altering subsequent generations of progenitor cells, leading to the development of cancer through changes in mitotic activity, apoptosis, cellular assembly, and signaling.26 Although it should be noted that while the presence of the cagA protein doubles the risk of gastric cancer, cagA - negative strands also increase the risk of distal gastric cancer.27 Additional H pylori virulence factors include babA2, which encodes bacterial adhesion with gastric epithelial cells, and vacuolating cytotoxin A, which is encoded by the gene vacA.28, 29 H pylori strains carrying some combination of the babA2, cagA, and vacA genes were associated with the highest risk of developing intestinal metaplasia.

Telomeres have recently emerged as a read - out of human cellular aging and their shortening actually contributes, along with other factors, to various common age - associated diseases.

LAMP2A: The A variant of lysosome - associated membrane protein 2 is a receptor involved in the cellular maintenance processes of autophagy, but levels decrease with age, and in at least some species this appears to be one of the factors involved in the age - related decline of autophagy.

Long associated with enabling the proliferation of cancer cells, the ancient cellular survival response regulated by Heat - Shock Factor 1 (HSF1) can also turn neighboring cells in their environment into co-conspirators that support malignant progression and metastasis.

The amyloidolytic response was associated with a pronounced infiltration of the amyloidoma with neutrophils and putatively involved opsonization of fibrils by the antibody, leading to cellular activation and release of proteolytic factors.

First, Nanog opened two key cellular pathways, known as Rho - associated protein kinase (ROCK) and Transforming growth factor beta (TGF - β).