Not exact matches
Overall stool
microbiome community composition was characterized using generalized UniFrac analysis.30 Controlling for the effects of feeding method, delivery mode was strongly
associated with infant
gut microbiome composition (P <.001; Q <.001)(Figure 1A).
Oligosaccharides in breast milk are thought to promote Bifidobacterium growth, 35 and decreased Bifidobacterium in infancy has been found to be
associated with an increased risk for being overweight at age 10 years.36 Many formulas are supplemented with prebiotics such as short - chain galacto - oligosaccharides and long - chain fructo - oligosaccharides that increase the overall representation of Bifidobacterium in the
microbiome of formula - fed infants, and similar to breast milk, promote lactate and short - chain fatty acid prevalence in the infant
gut (reviewed in the study by Oozeer et al37).
The researchers explain that a high fat diet boosts cell metabolism, including the release of inflammatory chemicals, as well as influencing the
gut microbiome and
associated immunity.
Bread affects clinical parameters and induces
gut microbiome -
associated personal glycemic responses.
Alternatively, a combination of treatments might work, Hunt says, possibly using a probiotic to modulate the
gut microbiome, and an anti-inflammatory drug to dampen the immune response and problems
associated with immune activation.
«Early life exposure to lead causes a long lasting impact on
gut microbiome, and the change of
gut microbiome may partially contribute to the increased body weight in adult life,» said lead author Chuanwu Xi,
associate professor of environmental health science.
Since the bacteria are
associated with contributing to good health, Mangalam and his colleagues wondered whether those with a chronic autoimmune disorder, such as multiple sclerosis, would then have a
gut microbiome that is different than the
microbiome found in healthy individuals.
«Greater diversity of bacteria in the
gut microbiome is
associated with both a higher response rate to treatment and longer progression - free survival,» said study leader Jennifer Wargo, M.D.,
associate professor of Surgical Oncology at MD Anderson.
Reducing this
gut -
associated inflammation has been a goal of clinicians and researchers, and rebalancing the
gut microbiome has shown promise in small - animal studies.
«We set out to find out about human genes that are implicated in the regulation of the
gut microbiome, and we found some that are,» says senior author Ruth Ley, an
Associate Professor in the Department of Microbiology at Cornell University and the study's senior author.
Scientists at the Science Foundation Ireland - funded APC
Microbiome Institute at University College Cork, Ireland, have shown that, at least in mice,
gut bacteria play a key role in regulating abdominal pain and its
associated changes in the brain and spinal cord.
As mounting evidence continues to suggest that the makeup of a person's
gut microbiome may influence his or her risk for obesity, Loomba and team began to wonder if the
gut microbiome might also be linked to obesity -
associated liver disease.
A gene
associated with risk for Alzheimer's disease influences the
gut microbiome of mice, potentiating a novel treatment strategy (Ishita Parikh, abstract 476.02, see attached summary).
Anthony Fiumera,
associate professor of biological sciences, and Gretchen Mahler, assistant professor of biomedical engineering, are collaborating on a research project funded by a Binghamton University Transdisciplinary Areas of Excellence (TAE) grant to discover the role ingested nanoparticles play in the physiology and function of the
gut and
gut microbiome.
«We might someday be able to manipulate the
gut microbiome, and in particular Enterococcus faecalis, to attenuate alcohol - related liver disease
associated with gastric acid suppression,» Schnabl said.
«Our stomachs produce gastric acid to kill ingested microbes, and taking a medication to suppress gastric acid secretion can change the composition of the
gut microbiome,» said senior author Bernd Schnabl, MD,
associate professor of gastroenterology at UC San Diego School of Medicine.
While strides have been made in our effort to understand the importance of the complex human
microbiome, the exact functions of the majority of our
gut associates remain unknown, as is their impact on our metabolism and overall physiology.
Recent work by Gordon's group, for example, demonstrates that the commensal
gut microbiome of an individual influences the efficiency of energy harvesting from ingested foodstuffs and, as a result, can directly influence the extent of weight gain
associated with food consumption (Turnbaugh et al, 2006).
For example, lower diversity of the
gut microbiome has been
associated with obesity and inflammatory bowel disease (IBD), and higher diversity in the vagina with bacterial vaginosis.
A few interesting articles in early life human
microbiome, plus: A comparison between Staphylococcus epidermidis commensal and pathogenic lineages from the skin of healthy individuals living in North American and India; A new tool to reconstruct microbial genome - scale metabolic models (GSMMs) from their genome sequence; The seasonal changes in Amazon rainforest soil
microbiome are
associated with changes in the canopy; A specific class of chemicals secreted by birds modulates their feather
microbiome; chronic stress alters
gut microbiota and triggers a specific immune response in a mouse model of colitis; and evidence that the short chain fatty acids profile in the
gut reflects the impact of dietary fibre on the
microbiome using the PolyFermS continuous intestinal fermentation model.
Human
gut microbiome Gut microbiome composition in lean patients with NASH is associated with liver damage independent from caloric intake: a prospective pilot study — Sebastião Mauro Bezerra Duarte — Nutrition, Metabolism and Cardiovascular Disea
gut microbiome Gut microbiome composition in lean patients with NASH is associated with liver damage independent from caloric intake: a prospective pilot study — Sebastião Mauro Bezerra Duarte — Nutrition, Metabolism and Cardiovascular Disea
Gut microbiome composition in lean patients with NASH is
associated with liver damage independent from caloric intake: a prospective pilot study — Sebastião Mauro Bezerra Duarte — Nutrition, Metabolism and Cardiovascular Diseases
Fecal microbiota are a subset of the microorganisms present in the gastrointestinal tract that are shed during defecation, and as such give much information about an individual's core
gut microbiome as well as allochthonous bacteria
associated with ingested food, water and very likely, air.
Read «11 Health Problems That Can Start In Your
Gut» for the full list of health problems
associated with
microbiome dysfunctions.
Scientists have already understood that the
gut microbiome is
associated with metabolic markers and type II diabetes.
Alterations in
gut microbiome composition and barrier function are
associated with reproductive and metabolic defects in women with polycystic ovarian syndrome (PCOS): A pilot study.
The delicate balance between the human
microbiome and the development of psychopathologies is particularly interesting given the ease with which the
microbiome can be altered by external factors, such as diet, 23 exposure to antimicrobials24, 25 or disrupted sleep patterns.26 For example, a link between antibiotic exposure and altered brain function is well evidenced by the psychiatric side - effects of antibiotics, which range from anxiety and panic to major depression, psychosis and delirium.1 A recent large population study reported that treatment with a single antibiotic course was
associated with an increased risk for depression and anxiety, rising with multiple exposures.27 Bercik et al. 28 showed that oral administration of non-absorbable antimicrobials transiently altered the composition of the
gut microbiota in adult mice and increased exploratory behaviour and hippocampal expression of brain - derived neurotrophic factor (BDNF), while intraperitoneal administration had no effect on behaviour.
Unlike Reset Your Weight, the GAPS diet is very food restrictive in order to completely heal the
gut microbiome and
associated diseases; Reset Your Weight is a flexible, more long term approach specific to weight loss where overall good health is just one of the rewards!
In particular, alterations of the
gut microbiome can activate proinflammatory cytokines and increase intestinal permeability, leading to the development of insulin resistance, which has also been
associated with AD.
In fact, exactly how the
gut microbiome «interacts with foods to produce health conditions» is considered a new and dynamic area for further research by individuals on all sides of the red meat - colon cancer debate.10 For example, researchers at Harvard Medical School are studying fecal samples to assess the impact of red meat intake on
gut microbes and their byproducts, which the researchers speculate may influence «biological pathways
associated with colorectal cancer and other digestive diseases.»
The
microbiome community constituents can increase inflammation that is being
associated with Western diseases such as obesity and Type 2 Diabetes, autoimmune disease (RA, IBD, MS...) asthma, and here, autism, cardiac and metabolic metabolic diseases, and
gut - brain axis related illnesses such as anxiety and depression.
These are just some of the negative health effects
associated with alcohol, but let's get back to the main topic... how to protect the
gut microbiome from damage.
The presence of BPA in dogs was
associated with changes to their
gut microbiome and metabolism, the researchers found.
A number of studies have shown that variations in the human
gut microbiome are
associated with different diet compositions as well as a number of medical conditions.
Dr. Jasmohan Bajaj discusses the relationship between the microorganisms in the
gut and cirrhosis, and how
microbiome analysis can be used to predict the risk of cirrhosis -
associated hospitalizations.