Sentences with phrase «associated lymphoid»

While bacteria also live in our mouths, on our skin and in our urogenital tract, more than 70 percent take up residence in the mucosal tissue lining of the gut, which is known as the gut - associated lymphoid tissue, or GALT.

Normally, the immune system is prevented from acting on these whole protein molecules by the gut - associated lymphoid tissue, better known as GALT.

Proposed causes for human IBD include defective immunoregulation of the gut - associated lymphoid tissue that may be precipitated by permeability defects, 14 infectious and parasitic agents, 15,16 and dietary allergies.13, 17 There is provocative evidence from clinical observations and animal models to incriminate normal luminal bacteria or bacterial products in the initiation and perpetuation of canine IBD.18, 19 The clinical response to hypoallergenic or elimination diets suggest that dietary factors may influence the pathogenesis of canine IBD.8 - 11 The term «hypoallergenic» refers to a diet that is generally free of additives and preservatives, and contains a hydrolyzed protein source.

This peptide can gain access to the gut - associated lymphoid tissue, is recognized by an enzyme called transglutaminase, and this complex stimulates a T - cell mediated immune response, perpetuating chronic inflammation and autoimmunity.

Together with the gut - associated lymphoid tissue and the neuroendocrine network, the intestinal epithelial barrier, with its intercellular tight junctions, controls the equilibrium between tolerance and immunity to non-self antigens.

This activates the mesenteric lymph nodes and gut - associated lymphoid tissue (GALT) and instigates a downstream inflammatory cascade.

GALT stands for gastric associated lymphoid tissue, and MALT, mucosal associated lymphoid tissue.

Skin was once thought to be just a physical barrier from the outside world, though the existence of skin - associated lymphoid tissue shows that it is much, much more.

As things make their way through your digestive system, your gut - associated lymphoid tissue, or GALT, which is the term for the immune system in your gut, reviews everything to check for potentially harmful substances.

The aim of this study is to determine whether a 20 - week treatment course with 1 μg / kg / week of pegylated interferon alpha 2 b (peg - IFN - α2b) will reduce the levels of HIV - 1 proviral DNA levels in circulating PBMC and mucosa - associated lymphoid tissue (MALT) in HIV - infected individuals receiving long - term anti-retroviral therapy (ART).

Included patients had three subtypes of disease, mucosa - associated lymphoid tissue, nodal, and splenic.

A fact sheet about the relationship between H. pylori infection and gastric cancer, gastric mucosa - associated lymphoid tissue (MALT) lymphoma, and other cancers.

The diagnosis of 6 cases were as follows; three diffuse large B cell lymphomas, two mucosa - associated lymphoid tissue lymphomas and one of other B cell neoplasias.

Inductive sites include regions such as mucosa - associated lymphoid tissue (MALT) and local / regional mucosa - draining lymph nodes, where antigens from mucosal surfaces stimulate naive T and B lymphocytes.

Distribution of rotavirus - specific memory B cells in gut - associated lymphoid tissue after primary immunization.

Induction of rotavirus - specific memory B cells in gut - associated lymphoid tissue after intramuscular immunization.

Oral inoculation of mice with low doses of microencapsulated, noninfectious rotavirus induces virus - specific antibodies in gut - associated lymphoid tissue.

It causes gastritis, peptic ulcers, stomach cancer, and mucosa - associated lymphoid tissue lymphoma.

About 80 % of our immune system resides in our gut, specifically in the GALT (gut - associated lymphoid tissue), which protects the body from invasion of pathogenic bacteria, fungi, and viruses.

Not exact matches

Currently, most genetic mutations associated with lymphoid cancers have been identified.

Fully implemented targeted sequencing - based assays in routine diagnostic pathology laboratories are currently lacking in lymphoid cancer care,» explained Christian Steidl, MD, Senior Scientist at the BC Cancer and Associate Professor in the Department of Pathology and Laboratory Medicine, University of British Columbia, Vancouver, Canada.

Gregory F. Sonnenberg, PhD, research associate in the Department of Medicine, Gastroenterology Division, and the Institute for Immunology at the Perelman School of Medicine, University of Pennsylvania, with postdoctoral researcher Matthew Hepworth, PhD, report in Nature that innate lymphoid cells (ILCs) directly limit the response by inflammatory T cells to commensal bacteria in the gut of mice.

Masters et al. discuss the often overlooked contribution of the stromal microenvironment as an extrinsic factor to immunosenescence and inflammation.12 Accumulation of senescent stromal cells which demonstrate the senescent associated secretory phenotype (SAPS), may alter tissue structure and function, and increase local inflammation.13 The impact of altered lymphoid stromal microenvironment may be widespread and include altered haematopoiesis, reduced lymphatic flow and disrupted secondary lymphoid organisation, which consequently will alter antigen transportation and presentation to T cells.12

Diagnosis of BPDCN was confirmed by the positivity of the cells for CD4 and CD56, along with other markers that are more restricted to plasmacytoid dendritic cells (such as CD123), and the negativity of the cells for lymphoid, NK and myeloid lineage - associated antigens.

Clonality findings could often occur in some reactive inflammatory conditions such as Helicobacter - associated gastritis or lymphoid hyperplasia of the skin.

This is in accordance with previous reports that decitabine and 5 - azacytidine produce a marked synergistic effect in combination with suberoylanilide hydroxamic acid and romidepsin in T - lymphoma cell lines by modulating cell cycle arrest and apoptosis.26, 27 As a mechanism of action, KMT2D mutations of B - lymphoma cells promote malignant outgrowth by perturbing methylation of H3K4 that affect the JAK - STAT, Toll - like receptor, or B - cell receptor pathway.28, 29 Here our study indicated that dual treatment with chidamide and decitabine enhanced the interaction of KMT2D with the transcription factor PU.1, thereby inactivating the H3K4me - associated signaling pathway MAPK, which is constitutively activated in T - cell lymphoma.13, 30,31 The transcription factor PU.1 is involved in the development of all hematopoietic lineages32 and regulates lymphoid cell growth and transformation.33 Aberrant PU.1 expression promotes acute myeloid leukemia and is related to the pathogenesis of multiple myeloma via the MAPK pathway.34, 35 On the other hand, PU.1 is also shown to interact with chromatin remodeler and DNA methyltransferease to control hematopoiesis and suppress leukemia.36 Our data thus suggested that the combined action of chidamide and decitabine may interfere with the differentiation and / or viability of PTCL - NOS through a PU.1 - dependent gene expression program.

LEUKOCELL 2 is a multiple viral antigen vaccine for vaccination of healthy cats 9 weeks of age or older as an aid in preventing persistent viremia, lymphoid tumors caused by feline leukemia virus (FeLV) and diseases associated with FeLV infection.

However, not all lymphoid cancers are associated with infections, so other genetic and environmental factors are also important.

Some types of lymphoid cancer in dogs are also associated with virus infection.