Sentences with phrase «association analysis identifies»

299/4: 30 Large - scale exome chip association analysis identifies novel type 2 diabetes susceptibility loci and highlights candidate effector genes.

Genome - wide association analysis identifies novel loci for chronotype in 100,420 individuals from the UK Biobank.

for article Large - scale association analysis identifies 13 new susceptibility loci for coronary artery disease.

«Gene variants modifying Huntington's symptom onset may lead to new therapeutic strategies: Genome - wide association analysis identifies sites associated with earlier - or later - than - expected symptom appearance in human patients.»

Not exact matches

For example, Clem Yates, sourcing and supply director of Off - Piste Wines, is going to talk about private label & bulk strategies for importers and distributors and how to meet the store brand challenge, in private label & channel conflict; Andrew Shaw, Group Wine Buying Director, Conviviality PLC will talk about bottled in market strategy and how suppliers can partner with Conviviality; Florian Ceschi, Director of Ciatti Europe will give a detailed statistical analysis of the current bulk market and will identify opportunities where producers and negociants can take advantage of; David Richardson, Regulatory & Commercial Affairs Director, The Wine and Spirit Trade Association (WSTA) will speak about regulatory issues specific to bulk products compared to cased goods.

To determine whether the presence and strength of the associations between individual risk factors and severe PPH vary among women undergoing prelabor CD or intrapartum CD, stratified analyses are needed according to CD subtype.To identify risk factors for severe PPH within 2 distinct CD populations, prelabor CD and intrapartum CD, we performed 2 case - control studies.

Had the aim of this analysis been to identify characteristics associated with PPH, clearly these covariates would have been included (as would many of the maternities excluded from the analysis as described earlier), so it would not be appropriate to use these results to draw conclusions about the association between PPH and covariates other than intended place of birth.

While the UniFrac analyses we performed suggest independent associations between microbiome composition and both delivery mode and feeding method, the substantial overlap between the communities defined by both factors suggests that there are other important drivers of microbiome community composition that remain to be identified in future analyses.

Meta - analyses of genome - wide association studies conducted in these ethnically - diverse populations identified a total of 878 genetic variants belonging to 18 loci associated with asthma risk.

The authors identified 68 publications meeting criteria for inclusion in the analysis: 59 reporting the prevalence of preoperative mental health conditions (65,363 patients) and 27 reporting associations between preoperative mental health conditions and postoperative outcomes (50,182 patients).

Although the team controlled for these factors in the analyses, the possibility of a partial confounding effect on the associations identified in the study can not be ruled out.

While several studies in the intervening years have investigated whether particular genes were responsible for modifying HD onset, this is the first to employ genome - wide association (GWA) analysis, which scans an individual's whole genome to identify chromosomal regions containing variants that are associated with the disease traits that are being studied.

Using a genome - wide association study (GWAS) that includes 1600 individuals living in Tanzania, Botswana, or Ethiopia, the authors identified regions of the genome that contribute to skin color variation and carried out a series of analyses to pinpoint the responsible genes.

GWAS meta - analysis identified an association between the gene TLR1 and H pylori seroprevalence, «a finding that requires replication in non-white populations,» the authors write.

Genome - wide association analysis comparing affected and unaffected PWC with the SOD1 mutation identified a haplotype within the gene «SP110 nuclear body protein'that was associated with increased risk of developing DM and early age of onset.

Corresponding author, Dr Seth Weinberg says «Our analysis identified several genetic associations with facial features not previously described in earlier genome - wide studies.

This research directly responds to a 2016 pharmacoepidemiologic analysis conducted using a large German health insurance database, which identified an association between dementia and long - term PPI use; however, these findings could not illustrate that PPIs caused dementia.

The study draws on an earlier analysis the lab conducted for the Western Governors» Association to identify areas where renewable resources are the strongest, most consistent, and most concentrated, and where development would avoid protected areas and minimize the overall impact on wildlife habitat.

Previous genetic studies have examined the association of aspirin, NSAIDs, or both with colorectal cancer according to a limited number of candidate genes or pathways.6 - 10 Thus, to comprehensively identify common genetic markers that characterize individuals who may obtain differential benefit from aspirin and NSAIDs, we conducted a discovery - based, genome - wide analysis of gene × environment interactions between regular use of aspirin, NSAIDs, or both and single - nucleotide polymorphisms (SNPs) in relation to risk of colorectal cancer.

In this study, genes identified as differentially expressed by SAM analysis were examined for their biologic association to the gene ontology (GO) categories [34] as defined by the GO Consortium [33].

In the associated paper, Vitkup, Iossifov and others use a novel form of analysis called NETBAG (network - based analysis of genetic associations) to identify «the large biological network of genes affected by rare de novo CNVs in autism.»

Comparative genomic analysis from 82 wild and wild - derived species grouped by microhabitat - use identified variation corresponding with one of these QTL, further supporting broad association with habitat use across the Malawi cichlid radiation.

This issue was identified by follow - up on likely «false - positive» genetic associations with genome - wide statistical significance in case - control analysis.

Therefore, mining associated molecular markers via association analysis might be a more powerful approach for identifying causative variation.

We show how the HapMap resource can guide the design and analysis of genetic association studies, shed light on structural variation and recombination, and identify loci that may have been subject to natural selection during human evolution.

Twelve type 2 diabetes susceptibility loci identified through large - scale association analysis

An Italian association study and meta - analysis with previous GWAS confirm WNT4, CDKN2BAS and FN1 as the first identified susceptibility loci for endometriosis.

SNP & Variation Suite offers a complete set of tools for processing raw intensity data, identifying regions of copy number variation (CNV), visualizing copy number data, and performing association analyses on a variety of copy number covariates.

Despite type 2 diabetes having been well studied by genome - wide association studies in other populations, analysis in Mexican and Latin American individuals identified SLC16A11 as a novel candidate gene for type 2 diabetes with a possible role in triacylglycerol metabolism.

Genome - wide association analyses in 128,266 individuals identifies new morningness and sleep duration loci.

We identify three loci and seven genes associated with insomnia complaints, with the associations for one locus and five genes supported by joint analysis with an independent sample (n = 7,565).

Veröffentlichung Q. Fan et al., Meta - analysis of gene - environment - wide association scans accounting for education level identifies additional loci for refractive error, Nature communications 7, 11008, 6.

The genes were identified through population - and genome - wide linkage scans and association analyses of at - risk haplotypes utilizing genetic and clinical data from the 17,000 participants in deCODE's obesity program in Iceland.

The EBV genetic variants identified here provide a basis for future more directed analysis of association of specific EBV variation with EBV biology and EBV associated diseases.IMPORTANCE Incidence of diseases associated with EBV varies greatly in different parts of the world.

In response to the article authored by Dr. Vladimir Kogan of Ohio State University, «Value Added vs. Similar Students» Measures: Comparing Two Methods for Holding Ohio Schools Accountable,» the California Charter Schools Association (CCSA) has identified significant misrepresentations and analysis errors by Dr. Kogan.

Fisher Exact analysis, comparing genotypes of cases to controls, identified an association signal on CFA16 (Figure 3) extending over 6 Mb and including 28 SNPs that exceeded the Bonferroni corrected significance threshold -LRB-- Log10 (p) range = 6.39 — 10.09, Table 5).

Whole genome association analysis studies that utilize single nucleotide polymorphism (SNP) markers have been used to identify the molecular causes of various traits and conditions including genetic mutations within breeds that cause coat color variations [15], hairlessness [25] and defects in spinal development [26].

Molecular genome - wide association analyses have identified single nucleotide polymorphisms that segregate with the boldness - shyness axis in dogs [10, 11].

Medical Affairs Liaison — Duties & Responsibilities Provide guidance and leadership with respect to the diagnosis and resolution of various issues in response to incidents reported by customers, working efficiently and effectively to implement related solutions and maintain high - quality customer service Administer all quality control functions while interacting professionally with outside contacts, including firm public relations professionals, representatives, client associates and other parties, providing relevant information, materials and support as needed Identify and deconstruct issues utilizing honed problem resolution techniques, collaborating with other professionals to address uncovered issues and shortfalls while acting as internal clinical and product - related expert Manage and oversee the development and implementation of critical systems and processes while coordinating support and customer service functions, working effectively to utilize all available resources and maintaining all relevant information Review proposed modifications to client operating environments, implementing fixes and resolutions to minimize service disruptions on an on - going basis, clearing duplicated and out - dated entries, and performing general account management functions Participate in the administration of various organizations, clinics, associations and other groups, assessing operational strategies regularly Assist in the performance of related analyses and needs - based assessments of product gaps, service requirements and operations - related areas to develop and implement required projects while determining the feasibility and functionality of proposed solutions Collaborate with sales and marketing professionals to drive revenue growth, improve firm visibility, expand product markets and integrate valuable customer feedback into future research and development Utilize talent among team members with effective communication and the promotion of a performance - based work environment Communicate all issues and user feedback to members of departments teams and vendor representatives as needed Create and maintain issue - tracking and resolution databases while auditing all entries for accuracy and completeness Develop and maintain a strong working knowledge of all relevant products, services, industry trends, tools and related information Lead through example with consistent work ethic, attitude, professionalism, and commitment to firm success

Finally, in case of redundant predictors (in comparison with the bivariate association low β coefficient / Wald statistic), a second regression analysis with a stepwise selection procedure was run to identify the best independently contributing predictors.

A logistic regression analysis was used to identify variables having a significant independent association with an improvement of 50 % or more in positive psychotic symptoms.

The aims of the analyses presented in this study were 1) to explore possible associations between the coping resources with achieved copying behaviors,... quality of life, pain - related factors and socio - demographic characteristics and 2) to identify patients with back pain who use different coping resources and to describe their respective socio - demographic and clinical characteristics.

The fact that «parental alienation syndrome» is not identified in the Diagnostic and Statistical Manual of the American Psychiatric Association, Fifth Edition (DSM - V), for example, does not mean that parental alienation does not exist; as Warshak's consensus statement and other meta - analyses have demonstrated, parental alienation is much more widespread than is commonly assumed.

Multivariate logistic regression analyses examined parity progression by birth order, while multinomial logistic regression was used to identify associations between sex composition and use of permanent, temporary and traditional contraceptive methods.

The main results can be summarized as follows: (1) Synchrony during early mother - child interactions has neurophysiological correlates [85] as evidenced though the study of vagal tone [78], cortisol levels [80], and skin conductance [79]; (2) Synchrony impacts infant's cognitive processing [64], school adjustment [86], learning of word - object relations [87], naming of object wholes more than object parts [88]; and IQ [67], [89]; (3) Synchrony is correlated with and / or predicts better adaptation overall (e.g., the capacity for empathy in adolescence [89]; symbolic play and internal state speech [77]; the relation between mind - related comments and attachment security [90], [91]; and mutual initiation and mutual compliance [74], [92]-RRB-; (3) Lack of synchrony is related to at risk individuals and / or temperamental difficulties such as home observation in identifying problem dyads [93], as well as mother - reported internalizing behaviors [94]; (4) Synchrony has been observable within several behavioral or sensorial modalities: smile strength and eye constriction [52]; tonal and temporal analysis of vocal interactions [95](although, the association between vocal interactions and synchrony differs between immigrant (lower synchrony) and non-immigrant groups [84]-RRB-; mutual gaze [96]; and coordinated movements [37]; (5) Each partner (including the infant) appears to play a role in restoring synchrony during interactions: children have coping behaviors for repairing interactive mismatches [97]; and infants are able to communicate intent and to respond to the intent expressed by the mother at the age of 2 months [98].