The phrase
"asymmetric cell" means that the cell is not the same on both sides. It has a different shape, structure, or function on one side compared to the other.
Full definition
In particular, we are investigating whether, and how, Numb and endocytosis - based mechanisms are involved in the regulation of
asymmetric cell division of human breast stem cells.
«Live cell imaging
of asymmetric cell division in fertilized plant cells: Insight into why leaves grow up and roots grow down in flowering plants.»
She also investigates
how asymmetric cell division impacts on the cellular potential to give rise to multiple lineages in vivo.
Li and her colleagues also determined that the association of aggregates with mitochondria gradually declines in the mother budding yeast cells with advanced replicative age, likely contributing to their diminished ability to rejuvenate
through asymmetric cell division.
Symmetry breaking transitions on curved surfaces are found in a wide range of dissipative systems, ranging
from asymmetric cell divisions to structure formation in thin films.
The group's results show that MTs are responsible for elongation of the zygote along the top - bottom axis, whereas F - actin plays a role in moving the nucleus towards the top part of the zygote, to make it ready
for asymmetric cell division.
«We were able to show by live cell imaging that polarization of the cell occurs after fertilization of the egg cell, and both MTs and F - actin play a role in
inducing asymmetric cell division to form the plant's body axis,» says Ueda.
Through live cell imaging, the group was able to visualize how fertilized egg cells in plants
undergo asymmetric cell division, which is responsible for determining the plant's body axis.
Vascular Cell Biology New Roles for BMP Signaling in Angiogenesis Victoria Bautch, University of North Carolina, Chapel Hill Coordination of angiogenesis
by asymmetric cell division Shane Herbert, University of Manchester
For his postdoc, he joined the laboratory of Lily and Yuh Nung Jan at University of California San Francisco to analyse the mechanisms
of asymmetric cell division.
This is the first time to visualize the real time event of
asymmetric cell division, and we were able to see other events such as cell elongation of the zygote and migration of the nucleus.»
This asymmetric cell division leads to small and large cells on the top and bottom part of the embryo, respectively.
The current study builds upon previous research, published by the Li lab in 2011 in Cell, that revealed that most aggregates of unfolded proteins are retained by the mother yeast cell during
the asymmetric cell division that characterizes this organism as well as stem cells.
An asymmetric cell division in non-stem cells can instead result in two daughter cells with very different fates, such as one large cell that reinitiates cell division prematurely and a much smaller cell that either grows very slowly or dies.
«I'd like to see what's different in
asymmetric cell division,» he says.
Not only did the group succeed in visualizing the real time events of zygote polarization and
asymmetric cell division, they were able to quantify the dynamic patterns of the cytoskeleton (i.e. formation of the ring structure and longitudinal array of MTs and F - actin, respectively).
The group succeeded in visualizing for the first time, how the cytoskeleton of plant egg cells is disassembled after fertilization and then reorganized to create a polarity in the cell that eventually leads to
asymmetric cell division.
«Although polarization and
asymmetric cell division of zygotes to form the body axis is a common phenomena found in algae, mosses, and flowering plants, the origin of cell polarity and how asymmetric cell division occurs have remained a mystery up to now,» says Dr. Minako Ueda, a lecturer at ITbM, Nagoya University and a leader of this research.
In order to investigate their specific roles, they used inhibitors of each protein to see their effect on zygote polarization and
asymmetric cell division.
Ana Fonseca (Corbeil, TUD)-- «New insights into cell migration and
asymmetric cell division of human hematopoietic progenitors» (2008)
In parallel, the roles of symmetric and
asymmetric cell divisions are investigated as a mechanism for governing stem cell self - renewal and differentiation during embryonic development and in the adult.
The First Cell Cycle of the Caenorhabditis elegans Embryo: Spatial and Temporal Control of
an Asymmetric Cell Division.
Asymmetric cell division in action.
«
Asymmetric cell division is the gold standard feature of normal stem cells,» Tang said.
Brummendorf TH, Dragowska W, and Lansdorp PM,
Asymmetric cell divisions in hematopoietic stem cells.
Centrosome asymmetry has been implicated in
asymmetric cell divisions.
We are also studying the mechanisms of
asymmetric cell division.
Phrases with «asymmetric cell»