The vast majority of cats will then experience a very long
asymptomatic phase while the virus «quietly» resides in its host cells.
Recent studies have revealed the existence of a long
asymptomatic phase, where the pathological changes leading to AD begin — at least - decades before the first symptoms of cognitive decline appear [2 — 4].
Not exact matches
Our group has 3 major goals: Develop novel therapeutic approaches based on centrosomal clustering To further develop our first prototype inhibitors of centrosomal clustering preclinically and to establish a robust and specific high throughput small molecule screen Discover key events in myeloma pathogenesis To investigate the pivotal transition from the pre-malignant,
asymptomatic to malignant, symptomatic stages of plasma cell dyscrasias in order to understand the pathophysiology and thereby identify novel targets Translate small molecule therapeutics from bench to clinical trials To evaluate novel agents in the preclinical setting and to initiate early
phase clinical trials in hematologic malignancies with focus on multiple myeloma
Thanks to virus - fighting drugs (antiretrovirals), this
asymptomatic period, known as the «chronic» or «latency»
phase of the disease, can essentially be extended indefinitely.
However, even during this «
asymptomatic»
phase, immune function is declining as the virus has a negative effect on the infected T - lymphocytes.
Oral medications can be initiated in the preclinical (
asymptomatic)
phase of dilated cardiomyopathy and in some cases, these medications can delay the progression of the disease to the development of congestive heart failure.