Sentences with phrase «at gladstone»

Research at Gladstone was supported by the NIH (National Institute of Neurological Disorders and Stroke; grants R00NS078118 and R01NS096369), the Gladstone Institutes, the Kavli Institute for Fundamental Neuroscience, the ILAE Michael Prize, the Department of Defense (grant EP150038), the National Science Foundation (grants 1608236, 1650113, 1144247), the Weill Foundation, the American Epilepsy Society, and the Dravet Syndrome Foundation.

SAN FRANCISCO, CA — Researchers at the Gladstone Institute of Cardiovascular Disease (GICD) and the University of California, San Francisco have unraveled a complex signaling process that reveals how different types of cells interact to create a heart.

«Heart failure afflicts many people worldwide, and we still do not have an effective treatment for patients suffering from this disease,» said Tamer Mohamed, PhD, first author on the study and a former postdoctoral scholar at Gladstone.

Meredith Calvert, PhD, is the director of the Histology and Light Microscopy Core at the Gladstone Institutes.

«Our study uncovered that alterations in the innate immune pathways could induce behaviors resembling obsessive - compulsive disorder in progranulin - deficient mouse models of FTD,» said Gan, who is also a senior investigator at Gladstone and a professor of neurology at the University of California, San Francisco.

«It was very gratifying to bring together investigators with different areas of expertise in this field and to share with them the successes we've had with our Behavioral Core at Gladstone.»

Yen - Sin Ang, PhD, a research scientist at the Gladstone Institutes, was awarded the Louis N. and Arnold M.

Scientists at the Gladstone Institutes and the University of California, San Francisco (UCSF), identified a common mechanism in two forms of neurodegeneration that affect young adults or the elderly.

Other scientists who participated in this research at Gladstone include Yu Huang, MD, PhD, Ian Spencer, PhD, Amy Foley, Vasanth Vedantham MD, PhD, Lei Liu and Ji - dong Fu, PhD.

Jae Kyu Ryu, PhD, Mario Merlini, PhD, Kim Baeten, PhD, Natacha Le Moan, PhD, Mark Petersen, MD, Dimitri Smirnoff, Catherine Bedard, MSc, Sara Gonias Murray, MD, and Jennie Ling also participated in this research at Gladstone.

«The SMDC has provided excellent services for scientists at Gladstone, but we were often waiting for access to their equipment and staff,» said Anke Meyer - Franke, PhD, a staff research scientist at Gladstone.

«The profound protective effects of progranulin against both amyloid - beta deposits and cell toxicity have important therapeutic implications,» said senior author Li Gan, PhD, an associate investigator at Gladstone and associate professor of neurology at the University of California, San Francisco.

Po - Lin So, a project manager and staff research scientist at Gladstone, describes how her love of science began in elementary school and continued to grow as she advanced academically and professionally.

In addition to directing his research program at Gladstone, Nakamura sees patients at the Parkinson's Disease and Movement Disorders Clinic at the UCSF, where he is an assistant professor.

At the Gladstone Lipid Clinic, which began as a resource for GICD, he provides patient care and teaches healthcare providers and community members about research related to blood lipid (cholesterol) disorders and preventing coronary heart disease (CHD).

Yu Zhang, a postdoctoral scholar at Gladstone, shares how training at Gladstone has benefitted her both professionally and personally.

Montana Horowitz, Fengrong Yan, Dr. Kurt Thorn, and Dr. Meredith Calvert comprise the outstanding Histology and Light Microscopy Core at Gladstone.

Combining the two most powerful biological tools of the 21st century, scientists at the Gladstone Institutes have modified how the genome of induced pluripotent stem cells (iPSCs) is read for the first time using a variation of the CRISPR - Cas9 system.

«We showed the fast - spiking interneurons act like gatekeepers for plasticity,» said Scott Owen, PhD, staff scientist in Kreitzer's laboratory at Gladstone.

Jae Kyu Ryu, PhD, Dimitri Smirnoff, Mark Peterson, MD, and Catherine Bedard also participated in this research at Gladstone, which received support from the National Multiple Sclerosis Society, the Nancy Davis Foundation for Multiple Sclerosis Research, the Pediatric Scientist Development Program, the March of Dimes and the National Institutes of Health (Grants NS052189 and NS066361).

I continue to work at Gladstone because it offers research and teaching opportunities that are simply outstanding.

«The damage from a heart attack is typically permanent because heart - muscle cells — deprived of oxygen during the attack — die and scar tissue forms,» said Dr. Srivastava, who directs cardiovascular and stem cell research at Gladstone, an independent and nonprofit biomedical - research institution.

A new study by scientists at the Gladstone Institutes shows that infection sites could affect the immune system's response to a virus and the way the virus spreads through the body.

At the Gladstone Institutes, neuroscientists rely on the Behavioral Core to research brain functions in both healthy and disease states, investigating the causes of neurological disorders and creating new therapies to overcome them.

Ogawa - Yamanaka Prize committee members include George Daley, PhD (professor of hematology / oncology and director of the Stem Cell Transplantation Program at Boston's Children Hospital), Hideyuki Okano, MD, PhD (chairman of Keio University Graduate School of Medicine), Shinya Yamanaka, MD, PhD (senior investigator at the Gladstone Institutes and director of the Center for iPS Cell Research and Application, Kyoto University), Srivastava, and Wernig.

Todd McDevitt is a senior investigator at Gladstone and lead author of the study.

«We found that people who carry progranulin mutations were nearly twice as likely to have retinal lipofuscin deposits than healthy people,» shared Michael Ward, MD, PhD, a former staff scientist at Gladstone and lead author of the study, as well as adjunct assistant professor of neurology at UCSF.

An expert committee of stem cell researchers made up of Dr. Daley, Hideyuki Okano, MD, PhD, chairman of Keio University Graduate School of Medicine, Marius Wernig, MD, PhD, an associate professor at the Stanford Institute for Stem Cell Biology and Regenerative Medicine, Deepak Srivastava, MD, director of the Gladstone Institute for Cardiovascular Disease and director of the Roddenberry Center for Stem Cell Biology and Medicine at the Gladstone Institutes, and Dr. Yamanaka, selected the first laureate.

At the two - day event, neuroscientists from across the nation gathered at Gladstone to present their discoveries about neurological conditions, such as Alzheimer's disease, Parkinson's disease, and autism.

«This new data indicate that latency is far from an accident — it is encoded in the virus's circuitry and is an evolutionarily advantageous strategy, likely increasing the odds of infection by a substantial amount,» Leor Weinberger, a coauthor and researcher at the Gladstone Institutes, a nonprofit focused on biomedical research, said in a statement.

«Alzheimer's is a complex disease involving multiple factors,» said Stephen Freedman, PhD, vice president of corporate liaison and ventures at Gladstone.

Michael Gill, PhD, director of the Behavioral Core at the Gladstone Institutes, presented a behavioral test that measures learning and memory at the 2016 Behavioral Neuroscience Symposium and Core Consortium Meeting held at Gladstone.

Underrepresented high school and community college students spent the summer at the Gladstone Institutes conducting hands - on research and learning about what it means to be a scientist.

Gladstone celebrates and honors its postdocs year - round by offering events and resources to help them thrive at Gladstone and beyond.

«So far, there has been a poor track record of moving things from preclinical discoveries into successful clinical trials,» says senior author Steve Finkbeiner, MD, PhD, a senior investigator at the Gladstone Institute of Neurological Disease and a professor of neurology and physiology at UCSF.

UCSF Graduate Student Genevieve Erwin also participated in this research at Gladstone, which was supported by grants from the National Institute of General Medical Sciences (#GM082901) and the National Heart, Lung and Blood Institute (#HL098179), A PhRMA Foundation Fellowship, a University of California Achievement Awards for College Scientists (ARCS) Scholarship and a gift from the Sam Simeon Fund.

Jeanne Paz, PhD, an assistant investigator at the Gladstone Institutes, has been awarded the prestigious Michael Prize, honoring her significant contributions to the field of epilepsy.

SAN FRANCISCO, CA — Scientists at the Gladstone Institutes today are announcing a research breakthrough in mice that one day may help doctors restore hearts damaged by heart attacks — by converting scar - forming cardiac cells into beating heart muscle.

In fact, scientists have gotten so good at gene sequencing that Nevan Krogan, PhD, a senior investigator at the Gladstone Institutes, is asking his colleagues to shift their focus to the interactions between the genes and the proteins they encode.

It is a historic time at the Gladstone Institutes; William S. «Bill» Price, III, has joined the Gladstone Trustees.

Our colleagues at Gladstone are using this knowledge to search for small molecules that can affect gene regulation and reverse some of the problems caused by the loss of these transcription factors.»

Shannon Noonan shares how a field trip motivated her to lead student outreach programs at Gladstone.

Saiyong Zhu, PhD, Shaohua Xu, PhD, Tao Xu, PhD, Yu Zhang, PhD, and Tianhua Ma, PhD also participated in this research at Gladstone, which was supported by the Roddenberry Foundation, the Eunice Kennedy Shriver National Institute of Child Health and Human Development, the National Energy Institute, the National Heart, Lung and Blood Institute, the National Institute of Mental Health / National Institutes of Health, the California Institute for Regenerative Medicine, the United States Department of Defense and the William K. Bowes, Jr..

Katherine Pollard, PhD, a senior investigator at the Gladstone Institutes, was invited by the OSTP to join a group of thought leaders to advise the NMI.

This phase will be implemented along with Sheng Ding, PhD, a senior investigator at Gladstone.

After learning about Sramek's goal to work in the medical field, his mentor at MESA encouraged him to apply for the Promoting Underrepresented Minorities Advancing in the Sciences (PUMAS) program at Gladstone.

Jorge Palop has been appointed to assistant investigator at the Gladstone Institute of Neurological Disease.

Now, scientists at the Gladstone Institutes have identified the molecular signals that direct this process.

The teams led by Pollard, Krogan, and Srivastava have teamed up with others at Gladstone to tackle this problem for congenital heart defects.

SAN FRANCISCO, CA — Scientists at the Gladstone Institute of Cardiovascular Disease (GICD) have found a new way to make beating heart cells from the body's own cells that could help regenerate damaged hearts.