Sentences with phrase «at site of»

This pigment is what darkens skin to form freckles and moles, creating a clearly - visible signal at the site of the implant, telling the person that something is wrong and they should visit a doctor.

Finch will incorporate its novel drug delivery technology to enable the targeted release of microbes at the site of the C. difficile infection in the colon.

Neutrophils recruit and activate Human Endothelial Colony Forming Cells at the site of vessel injury via PSGL - 1 and L - Selectin.

Microclimatic effects associated with the topography and vegetation patterns at the site of a borehole, along with local anthropogenic perturbations associated with land use change, can obscure the regional climate change signal.

Encapsulation allows for diffusion of pro-angiogenic cytokines and growth factors made by the hMSCs while maintaining them at the site of implantationâ $ ¦ Alginate encapsulated hMSCs attached to the heart with a hydrogel patch resulted in a highly significant improvement in left ventricular function after acute myocardial infarction.

1976 - An agreement is signed establishing a second outstation at the site of the Institut Laue - Langevin in Grenoble.

At a news conference attended by New York Mayor Michael Bloomberg, the authors unveiled the nearly complete fossil of a nine - month - old female primate that had been found at the site of Messel in Germany.

Additional evidence supporting the tumor - promoting role of inflammation is the observation that individuals with chronic inflammation are more susceptible to cancers at the site of that inflammation — e.g. patients with Crohn's disease show increased incidence of colorectal cancer.

We thus envisage the molecular mechanism of interallelic complementation to involve the exchange of XPD molecules within the TFIIH complex or turnover of TFIIH complexes containing different XPD molecules at the site of DNA damage during the course of the global genome as well as transcription - coupled repair of either UV - induced or endogenous DNA damage.

«After an injury to the cortex, chronic inflammation can emerge, not only at the site of the lesion, but also in the thalamus.

In order to determine whether cell division occurred in either the periphery of the corneal endothelium following mechanical wounding or at the site of the wound itself, corneas were tested with the AP - BrdU assay.

Unlike viral gene therapy, which permanently changes a person's genetic makeup, this approach is temporary and increases production of interleukin - 10 only at the site of the injection.

It's long been thought that white blood cells called macrophages destroy viruses at the site of an infection, like a mosquito bite.

MAIT cells accumulate at the site of bacterial infection and are protective in experimental infection models.

Next, they collected effluents from coal ash facilities at power plants in North Carolina and Tennessee and compared it to both coal ash residue they had previously collected at the site of the massive 2008 Tennessee Valley Authority power plant spill in Kingston, Tenn., and to the laboratory test results.

This study, led by Soo Young Kim and performed at the University of Texas at Austin and the University of California, Berkeley, found that such compensation produces structural brain changes at the site of the stroke in rats, limiting recovery of the injured side.

The continual flow of electrical current results in chemical reactions at the site of the electrodes delivering the signal, causing gas bubbles, corrosion and toxic byproducts to form.

Early signs of an MRSA infection may include redness and swelling at the site of the injection and sometimes pus leaking out, Shopsin said.

He proposed that upon Ca2 + binding, synaptotagmin opens a fusion pore at the site of the SNARE complex formation.

Wet - sieving at the site of Ras Mkumbuu, Pemba Island, Zanzibar, Tanzania.

When it finds a mismatch, it locks into place at the site of the error and recruits MutL to come and join it.

Using single molecule fluorescence methods, which allowed the researchers to watch one protein moving on one piece of DNA at a time, they determined that when MutS finds an error, it changes shape in a way that allows MutL to bind with it, holding it in place at the site of the mismatch.

Two ancient crania were unearthed about 4000 kilometers from Denisova Cave at the site of Lingjing in Henan province in China.

Then bone - making cells called osteoblasts and bone - absorbing cells called osteoclasts grow and sculpt new bone at the site of fracture.

«Historically, when treating early lung cancer with radiotherapy, progression at the site of the primary tumor was the most common failure resulting in suffering and death,» said lead study author Robert Timmerman, MD, professor and vice chair of the department of radiation oncology at the University of Texas Southwestern Medical Center in Dallas.

«There are more reactive glial cells and fewer functional neurons in the injury site,» Chen said, «so we hypothesized that we might be able to convert glial cells in the scar into functional neurons at the site of injury in the brain.

Scott's team designed a nanocarrier formulation that — after quickly forming into a gel inside the body at the site of injection — can continuously release nanoscale drug - loaded vehicles for months.

Early signs of Lyme disease include a distinctive circular «bulls - eye» rash at the site of the tick bite around three to 30 days after being bitten, although only one in three people develop this rash.

They were excavated more than 100 years ago at the site of Tebtunis (now Umm el - Breigat) in the Fayum region of Egypt.

Along with scar tissue, one of the main barriers to healing is the development of fluid - filled cysts at the site of the injury over the ensuing months.

By integrating the nanosponges into a hydrogel, we can retain them at the site of infection.»

The current studies are far less invasive, using surface ultrasound directed at the site of the clot from outside the body, which could potentially be performed by a medical technician.

The ultrasound penetrates through the chest tissue to hit and activate the intravenously infused microbubbles at the site of the blockage.

This helps ensure selective drug targeting only at the site of the tumor.

Previous field research by Bargar's team and collaborators at Lawrence Berkeley National Laboratory (LBNL) at the site of a former uranium mill in Rifle, Colorado, has provided a possible explanation for the longevity of the uranium contamination.

A new study published online today in Nature, led by dating experts at the University of Oxford in the United Kingdom (two of whom, Thomas Higham and Katerina Douka, are pictured here taking radiocarbon samples at the site of Chagyrskaya in Russia), concludes that Neandertals were entirely extinct by 39,000 years ago.

Patients who have prosthetic joints are at risk of an infection «seeding,» or anchoring, at the site of the metal, ceramic, or plastic device.

«Chernobyl: At site of world's worst nuclear disaster, the animals have returned.»

And because tumors typically have a leaky, ill - formed vasculature, the particles tend to leak out at the site of cancer tissue and be picked up and internalized inside tumor cells.

When DNA damage occurs in these cells, the GFP lights up at the site of the repairs.

The lung cancer drug — called gefitinib — helps by blocking a protein that is known to encourage cell growth, and which was found to be present in high levels at the site of ectopic pregnancies.

They also captured information on the presence of immune cells at the site of the tumor.

«Our observation that groups matched their compositions to the one optimal at their site of origin (regardless of their current habitat) is particularly important,» Pruitt and Goodnight write, «given that many respected researchers have argued that group selection can not lead to group adaptation except in clonal groups and that group selection theory is inefficient and bankrupt.»

A few have also developed cutaneous T - cell lymphoma at the site of old mustard burns.

We know hominins of this period had these, and an elephant skeleton with a wooden spear through its ribs was found at the site of Lehringen in Germany in 1948.»

Extracted from a sixteenth century pig found at the site of the Montsoriu Castle in Girona, the data obtained indicates that this ancient pig is closely related to today's Iberian pig.

But the most promising candidates — compounds called vaginal microbicides that thwart the virus at the site of infection — have failed repeatedly in clinical trials.

This only happened at the site of active synaptic transmission.

In Turkey, at the site of the eighth millenium B.C.E. settlement Çatalhöyük, the finest figurines of clay and stone were associated with the burials of high - status people in special shrines, whereas cruder figurines were found in houses [see «Women and Men at Çatalhöyük,» by Ian Hodder, on page 34].

In recent years, an excavation at the site of the Brochtorff Circle on Gozo has uncovered important evidence about the prehistoric rituals of death.