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Not exact matches
She believes her
research will give great value to a product that up to this time has been simply a waste product, the coconut residue, but which in fact has great
therapeutic value
at the fraction of the cost of expensive western medicines.
Dr. Janaki Gooneratne, the head of Food Technology
at the Industrial Technology Institute in Sri Lanka, conducted the
research while analyzing the
therapeutic value of coconut residue products in relation to heart disease.
New York City Councilman Antonio Olivieri, who died of cancer in 1980
at age 39, had lobbied for state medical marijuana use for
therapeutic research.
A
research group headed by Gustavo Turecki, professor of psychiatry
at McGill University in Montreal, Canada, recently used the platform to show that miRNAs can be used as prognostic markers for
therapeutic responses to an antidepressant medication in patients with major depressive disorder (3).
Of approximately 300 staff
at the Center for
Therapeutic Research, only nine postdocs and students are conducting basic research; the rest work in drug discovery and deve
Research, only nine postdocs and students are conducting basic
research; the rest work in drug discovery and deve
research; the rest work in drug discovery and development.
Gervais was so impressed by the apoptosis
research that he later approached Nicholson about doing a postdoc in his lab, which is based at the Merck Frosst Center for Therapeutic R
research that he later approached Nicholson about doing a postdoc in his lab, which is based
at the Merck Frosst Center for
Therapeutic ResearchResearch.
Richard Hargreaves, executive director of imaging
at Merck
Research Laboratories, says, «Nuclear imaging using radiotracers gives the opportunity to put your arms around proof - of - concept very early in a drug discovery and development program by focusing the selection of doses to study on those proven to deliver enough drug to the target
therapeutic sites.»
At a handful of sites across the country, after a four - decade hiatus, psychedelic
research is undergoing a quiet renaissance, thanks to scientists like Charles Grob who are revisiting the powerful mind - altering drugs of the 1960s in hopes of making them part of our
therapeutic arsenal.
«Targeting the drivers of aging and senescent cells may be a novel
therapeutic strategy to reduce hepatic steatosis and liver fibrosis in ALD patients,» commented co-author Gianfranco Alpini, PhD, Distinguished Professor in the Department of Medical Physiology
at Texas A&M College of Medicine, Senior
Research Scientist
at Central Texas Veterans Health Care System, and Director of the BSW DDRC.
Until now, EGFR inhibitors have only been effective
at treating the 10 to 15 percent of non-small cell lung cancers that have a variant of EGFR, but the two - drug combo could potentially work for all non-small cell lung cancers, explained Dr. John Minna, Director of the Hamon Center for
Therapeutic Oncology
Research and Professor of Internal Medicine and Pharmacology.
«Using approved therapies for one condition to treat another, or drug repurposing, offers new avenues to speed Parkinson's
therapeutic development,» said Dr Brian Fiske, senior vice president of
research programs
at MJFF.
«We are excited by the work of Dr. Pourdehnad and colleagues and believe these results are an important advance in understanding the role of myc pathway dysregulation in multiple myeloma, and ultimately allow for the development of
therapeutic strategies to address it,» said Jeffrey Wolf, MD, a UCSF blood disorder specialist and director of the Stephen and Nancy Grand Multiple Myeloma Translational Initiative
at UCSF, a sponsor of the
research.
University of Calgary researchers including Luchman, Weiss and Dr. Greg Cairncross — director of SACRI, and leader of the Terry Fox
Research Institute (TFRI) «Therapeutic Targeting of Glioblastoma research program at the university — are now working with cancer researchers Dr. Warren Mason (Princess Margaret Cancer Centre in Toronto) and Dr. Lesley Seymour (Director of the NCIC Clinical Trials Group's Investigational New Drug Program), and drug manufacturer AstraZeneca, to plan a clinical trial testing a similar, but newer, drug related to AZD8055 (called AZD2014), in combination with TMZ, in patients with gliob
Research Institute (TFRI) «
Therapeutic Targeting of Glioblastoma
research program at the university — are now working with cancer researchers Dr. Warren Mason (Princess Margaret Cancer Centre in Toronto) and Dr. Lesley Seymour (Director of the NCIC Clinical Trials Group's Investigational New Drug Program), and drug manufacturer AstraZeneca, to plan a clinical trial testing a similar, but newer, drug related to AZD8055 (called AZD2014), in combination with TMZ, in patients with gliob
research program
at the university — are now working with cancer researchers Dr. Warren Mason (Princess Margaret Cancer Centre in Toronto) and Dr. Lesley Seymour (Director of the NCIC Clinical Trials Group's Investigational New Drug Program), and drug manufacturer AstraZeneca, to plan a clinical trial testing a similar, but newer, drug related to AZD8055 (called AZD2014), in combination with TMZ, in patients with glioblastoma.
After a successful postdoc
at the Ontario Cancer Institute, where he developed a proprietary platform for the discovery of novel cancer
therapeutic agents, Bray was asked to join the former Amgen
Research Institute in Toronto (now called the Advanced Medical Discovery Institute and no longer part of the parent company) as the head of their quantitative biology group and act as liaison to Amgen Inc. in California.
Katerina Akassoglou, PhD, and her
research team
at the Gladstone Institutes uncovered a promising new
therapeutic strategy.
Now, a
research team based
at Nagoya University used plasma to activate Ringer's solution, a salt solution with existing
therapeutic functions, and showed that its lactate component had anti-tumor effects.
The
research is part of the
Therapeutic Hypothermia After Pediatric Cardiac Arrest (THAPCA) trials, which enrolled over 600 children over six years
at more than 40 clinical centers throughout the U.S., Canada and United Kingdom.
The paper, by S.S. Karuppagounder
at Burke Medical
Research Institute in White Plains, N.Y., and colleagues was titled, «
Therapeutic targeting of oxygen - sensing prolyl hydroxylases abrogates ATF4 - dependent neuronal death and improves outcomes after brain hemorrhage in several rodent models.»
«Our
research could lead to
therapeutic opportunities,» said Yang Xia, M.D., Ph.D., the study's senior author and a professor in the Department of Biochemistry and Molecular Biology
at the UTHealth Medical School.
«Physicians do use the database, but it's not yet common for them to use it for every prescription because it's still lacking a lot of information on pharmaceuticals,» said Lööf, chairman of the Drug
Therapeutic Committee
at the Centre for Clinical
Research in Västerås, which works with local physicians to provide drug therapy strategies.
Rod Kellems, Ph.D., study co-author and chairman of the Department of Biochemistry and Molecular Biology
at the UTHealth Medical School, added, «This
research provides insight into how red blood cells work, revealing that SphK1 - mediated elevation of S1P contributes to sickling and promotes disease progression and highlights potential
therapeutic opportunities for sickle cell disease.»
The one developed by Zhang and his team, including Ph.D. student Inga Haedicke, U of T Assistant Professor Hai - Ling Margaret Cheng and two
research groups (Dr. Timothy Scholl and Dr. Paula Foster) from Western University, can improve monitoring
at the cellular level, which is a crucial element in measuring the effectiveness of stem and
therapeutic cell treatments.
turned into 10 years of systematic
research to identify the enzyme PLK4 as a promising therapeutic target and develop a small molecule inhibitor to block it,» says Dr. Mak, Director of The Campbell Family Institute for Breast Cancer Research at the Princess Margaret Cancer Centre, University Health
research to identify the enzyme PLK4 as a promising
therapeutic target and develop a small molecule inhibitor to block it,» says Dr. Mak, Director of The Campbell Family Institute for Breast Cancer
Research at the Princess Margaret Cancer Centre, University Health
Research at the Princess Margaret Cancer Centre, University Health Network.
This clinical trial is the culmination of long - standing
research led by Professor John Greenwood
at the UCL Institute of Ophthalmology showing the potential
therapeutic benefits of using statins to treat autoimmune diseases such as multiple sclerosis and uveitis.
«It's the proof of concept that through
therapeutic vaccination we can really re-educate our T cells to control the virus,» says Beatriz Mothe, a clinician
at IrsiCaixa AIDS
Research Institute in Barcelona, Spain, who presented the results here
at the Conference on Retroviruses and Opportunistic Infections.
Expanding the
Therapeutic Window for Treatment As PI
at MSM, Ford takes what he learned during his training and applies it to stroke — caused by blockage or rupturing of arterial blood flow leading to or in the brain — and atherosclerosis — hardening of arteries over time due to fat - deposit build - up on their inner lining —
research.
The authors hope their hypothesis will promote
research to investigate the mechanisms that underlie this hypertension, as well as preventative and
therapeutic strategies for this potentially
at - risk population.
Blackburn, a cell biologist
at the University of California
at San Francisco, charges she was released for speaking out in favor of
therapeutic cloning and against federal funding restrictions on stem cell
research.
«It's probably premature to run large trials without evidence that they have a
therapeutic effect that [we] understand,» cautions Arnold Kriegstein, director of the Broad Center of Regenerative Medicine and Stem Cell
Research at the University of California, San Francisco.
The
research — published January 3, 2017 in the online journal eLife — was led by Joshua Galanter, MD, MAS, formerly an assistant professor of medicine, of bioengineering and
therapeutic sciences, and of epidemiology and biostatistics
at UCSF, who is now a scientist
at Genentech.
Dr Martin Reijns, Senior
Research Fellow at the MRC Human Genetics Unit, said: «We hope that this research will inform future studies into the development of improved therapeutic approaches
Research Fellow
at the MRC Human Genetics Unit, said: «We hope that this
research will inform future studies into the development of improved therapeutic approaches
research will inform future studies into the development of improved
therapeutic approaches.»
«The dBET1 and the dFKBP12 compounds are presently in a late stage of lead optimization for
therapeutic development in both cancer and non-malignant diseases,» says Prem Das, PhD, chief
research business development officer
at Dana - Farber.
«There's a huge body of
research showing that alcohol hand rinses are actually much better
at getting rid of bacteria than soap,» says Elaine Larson, a professor of pharmaceutical and
therapeutic research at the Columbia University School of Nursing.
A team of researchers
at Mayo Clinic and The Scripps
Research Institute in Florida have developed a new
therapeutic strategy to combat the most common genetic risk factor for the neurodegenerative disorders amyotrophic lateral sclerosis (ALS or Lou Gehrig's disease) and frontotemporal dementia (FTD).
«This mechanism may offer the potential to develop an entirely new
therapeutic approach,» says C. Ronald Kahn, M.D., Joslin's chief academic officer, Mary K. Iacocca Professor of Medicine
at Harvard Medical School and senior author of a paper on the
research published in the journal Nature.
«In recent years, several
therapeutic medicines have been developed that spur a person's own immune system to fight cancer,» said Raul Torres, PhD, professor of immunology
at National Jewish Health, and senior author on the paper, published in the October issue of Cancer Immunology
Research.
«In cases where you are trying to make
therapeutic decisions, you want to have some numbers that you can fall back on,» says Vincent Liu, a graduate student in Cima's lab
at MIT's Koch Institute for Integrative Cancer
Research and lead author of the paper.
She holds a Tier 2 Canada
Research Chair in Aging & Immunity, and investigates how changes in the immune system of older adults and vulnerable populations predispose them to pneumonia infection.The aim of Dr. Bowdish's research at McMaster University is to develop novel preventative and therapeutic strategies that reduce the burden of pn
Research Chair in Aging & Immunity, and investigates how changes in the immune system of older adults and vulnerable populations predispose them to pneumonia infection.The aim of Dr. Bowdish's
research at McMaster University is to develop novel preventative and therapeutic strategies that reduce the burden of pn
research at McMaster University is to develop novel preventative and
therapeutic strategies that reduce the burden of pneumonia.
The findings, being presented as part of a poster presentation
at the Annual Meeting of the American Association for Cancer
Research (AACR) being held in Philadelphia this week, could have
therapeutic implications specific to this rare form of the disease, say the authors.
These students and faculty work on a broad spectrum of
research problems that share
at least one of the four goals of Bio-X: to image and simulate life from molecules to mind, to restore the health of cells and tissues, to decode the genetics of health and disease, and to design
therapeutic devices and molecular machines.
The conference aims
at bringing together international experts from different fields of cancer
research to present and discuss new
therapeutic approaches regarding different tumor entities as well as new findings in the field of tumor biology seeking to incorporate innovative platforms into cancer
research.
Before he joined Moderna in 2013, Dr. Frederick was a Translational
Research group leader
at Aveo Oncology, focused on the generation of biomarkers for
therapeutic response prediction, as well as avenues to modulate the tumor microenvironment for
therapeutic benefit.
The meeting featured a keynote address from Bruce R. Conway, PhD, Director of the Robertson
Therapeutic Development Fund
at The Rockefeller University, as well as a panel discussion on best practices for translational science featuring Dr. Conway, Michael L. Batten, MD, MBA, of the JDRF T1D Fund, Andres Hurtado - Lorenzo, PhD, Director of Translational
Research at the Crohn's & Colitis Foundation, Elizabeth Schwarzbach, PhD, Vice President of Business Development
at NYSCF, and Caren A. Heller, MD, MBA, of the Crohn's & Colitis Foundation.
To help Gladstone discoveries successfully cross through the valley of death, the Hellman Family Foundation Alzheimer's
Research Program subsidizes the myriad of early - stage, de-risking tests necessary to make a drug candidate more attractive to pharmaceutical - industry partners, such as tests that reveal
at what concentrations a drug stops being
therapeutic and instead becomes toxic.
However, patients are now able to participate in two
research projects aimed
at understanding this disease in order to make discoveries which may lead to better
therapeutic options.
Previously Dr. Martini worked
at Shire plc in Lexington, Mass., as Senior Director of Discovery Biology and Translational
Research, Mass., focusing on fibrotic diseases of muscle, kidney, skin, lung, bone marrow and metabolic liver diseases, with particular emphasis on different
therapeutic modalities for pathway modulation.
In addition, Dr. Gudkov has presented these new data today
at the
Research Workshop of the Israel Science Foundation 2016 called Cellular Senescence: From Molecular Mechanisms to
Therapeutic Opportunities, which attracted top internationally recognized experts in senescence and aging.
Two recent developments involving the California Institute for Regenerative Medicine (CIRM) again serve to underscore the reality that adult and other non-embryonic avenues of stem cell
research are advancing
at a far more dramatic pace toward providing actual
therapeutic benefits for patients than is human embryonic stem cell
research (hESCR).
The study conducted in the laboratory of Don Cleveland, Ph.D., UCSD Professor of Medicine, Neurosciences and Cellular and Molecular Medicine and member of the Ludwig Institute for Cancer
Research, shows that
therapeutic molecules known as antisense oligonucleotides can be delivered to the brain and spinal cord through the cerebrospinal fluid (CSF)
at doses shown to slow the progression of ALS in rats.