The two drugs in combination haven proven to be highly effective, and since each of these drugs is
at a low dose side effects are rare.
Not exact matches
Because there are no standard dosages based on a child's weight, stimulants are usually started
at a
low dosage and gradually increased to find a child's best
dose, which «is the one that leads to optimal effects with minimal
side effects.»
This would help tamp down antibiotic resistance, while allowing doctors to
lower the dosage of antibiotics that are toxic
at high
doses and that produce nasty
side effects such as deafness and kidney damage.
But
at the
low doses used in their initial experiment the
side effects were not serious.
«We tested combinations because
lower doses of each drug can be used, potentially decreasing
side effects,» said Dr. Fish, a Professor in the Department of Immunology
at the University of Toronto.
MTX is commonly used
at low doses to treat inflammatory diseases including rheumatoid arthritis, Crohn's disease and psoriasis and has few
side effects.
Methylnaltrexone, a drug designed to reverse one of the most troubling problems caused by opium - based analgesics without interfering with pain relief, is rapidly effective
at low doses with no apparent
side effects report researchers from the University of Chicago Medical Center in the January 19, 2000, issue of JAMA.
January 18, 2000 Drug blocks opioid
side effects: Could improve palliative care Methylnaltrexone can reverse opioid - induced constipation without interfering with pain relief, is rapidly effective
at low doses and has no apparent
side effects.
How
dosing works Because patients can experience
side effects like dizziness and sleepiness, Charles E. Argoff, MD, director of the Comprehensive Pain Program
at Albany Medical Center, in Albany, N.Y., recommends that patients begin with the
lowest dose possible (75 mg twice a day).
It is added to the stack
at a
low dose which will decrease the amount of
side effects that occur when taken taken orally including upset stomach and
at high
doses liver problems.
At low doses, usually less than 4.5 mg per day, naltrexone is considered very safe and has few
side effects.
Some dogs experience marked
side effects, so it's important to start
at lower doses to ensure they aren't extremely sensitive to it.
High
doses of rapamycin are already used in humans to fight cancer and prevent organ - transplant rejection, but
at low doses, it has also been shown to slow aging and extend life span in several animals with few or no
side effects.
This could be a problem in patients with congestive heart failure or other patients who require sodium restriction May stunt growth if used in young, growing animals May
lower seizure threshold and alter mood and behavior
At high
doses, this medication can cause birth defects early in pregnancy, be irritating to the stomach or cause higher than normal blood sugar levels If your pet has received high
doses, it should not be vaccinated without your veterinarian's advice as the vaccine may not work or it may actually give your pet the disease you are trying to prevent Less common
side effects include weight gain, insomnia, panting, diarrhea, vomiting, elevated liver enzymes, pancreatitis and behavior changes Serious
side effects are not expected with routine use.
Because Medrol is given
at lower doses, these
side effects are typically minimized.