Sentences with phrase «at a novel mechanism»

Not exact matches

Meanwhile, Van den Eynde and his team are already hard at work looking for the other novel mechanisms of immune suppression in their model.

«This finding opens up a huge avenue of research in parrots, in trying to understand how parrots are processing the information necessary to copy novel sounds and what are the mechanisms that underlie imitation of human speech sounds,» said Mukta Chakraborty, a post-doctoral researcher in the lab of Erich Jarvis, an associate professor of neurobiology at Duke and a Howard Hughes Medical Institute Investigator.

A new study carried out under the direction of Professor Lutz Wiegrebe at the Department of Biology at Ludwig - Maximilians - Universitaet (LMU) in Munich sheds light on a novel mechanism that is employed by humans to estimate their relative distance from sound sources.

Researchers at the University of Alabama at Birmingham report the discovery of a novel mechanism in the brain involved in the formation of memory and learning.

Dr. Alan S. Cross, Professor of Medicine at University of Maryland School of Medicine, who was not involved in the research, shared his input: «This is a major conceptual breakthrough in our understanding of infection and immune disease mechanisms and may have implications for novel approaches to the treatment of other diseases characterized by cytokine storm.

Understanding the underlying protective mechanisms in the lower risk individuals could help design novel therapeutic strategies targeting those at higher risk of disease.

The question is — and it's a question at this point — can we learn from these novel biophotonic mechanisms that have evolved over millions of years of natural selection new approaches to making tunable and switchable photonic materials to more efficiently encode, transmit, and decode information via light?»

In the final step in bacterial cell division, constriction of the so - called Z - ring, an annular structure that forms on the plasma membrane near the midpoint of the cell, gives rise to the two daughter cells: A research team led by Erwin Frey, who holds the Chair of Statistical and Biological Physics at LMU, has now used mathematical modelling to understand the mechanism that drives formation of the Z - ring, and in so doing have uncovered a novel class of pattern - forming mechanism in biological systems.

Now, researchers at Johns Hopkins Medicine report that a novel laboratory tool that lets them find virus mutations faster and more efficiently than ever before has identified a biological mechanism that appears to play a big role in helping HCV evade both the natural immune system and vaccines.

This novel mechanism, in which the two parts of the prion protein have opposing functions, had not been fully appreciated before,» explained corresponding author David Harris, MD, PhD, professor and chair of the department of biochemistry at Boston University School of Medicine (BUSM).

In early 2012, Emmanuelle Charpentier, a little - known French microbiologist who would soon meet worldwide fame, contacted her old friend Rodger Novak to tell him about her recent studies at Umeå University in Sweden of the mechanisms behind a novel bacterial immune system.

«Identifying genetic mutations associated with disease risk is an effective way to better understand disease mechanisms, identify individuals at risk, and develop novel drug targets to treat the disease,» Dr. Peter added.

Based on these surprising therapeutic effects, the scientists initiated experiments aimed at unraveling the underlying molecular mechanisms of the novel combination therapy.

Researchers from the Department of Biomedicine at the University of Basel discovered novel mechanisms of cell migration by observing cells moving on lines of connective tissue.

«Next we aim to identify the exact biological mechanisms at these 15 novel sites in the genome that lead to the development of CAD,» Saleheen said.

Molecular microbiologists at the University of Southern California (USC) have uncovered intricate regulatory mechanisms within the cell that could lead to novel therapeutics for the treatment of cancer and other diseases.

A philosopher at Tufts University, Dennett advanced a novel perspective on the origin and mechanism of consciousness that, while not meeting the claim of the book (how could it?)

In this review topic, researchers looked at novel translational noise studies demonstrating the molecular mechanisms that may lead to impaired vascular function, recent epidemiologic evidence of noise - induced cardiovascular disease, and the non-auditory effects of noise and their impact on the cardiovascular system.

Researchers at the University of Illinois at Chicago have discovered a novel molecular mechanism that tightens the bonds between the cells that line blood vessels to form a leak - proof barrier.

Recognising a need to better understand the biology that produces ASD symptoms, scientists at Duke - NUS Medical School (Duke - NUS) and the National Neuroscience Institute (NNI), Singapore, have teamed up and identified a novel mechanism that potentially links abnormal brain development to the cause of ASDs.

Masters Student, Rotation, Dept. of Plant Pathology December 2005 — April 2006 Cornell University, Geneva, NY Principal Investigator: Dr. Chris Smart The lab focuses on the identification of novel plant defense mechanisms under field conditions and is looking at the relationship between pathogen and insect resistance.

Where research uncovers possible mechanisms for disease, those working in drug discovery can use these data to develop novel diagnostic or monitoring tools, to develop therapies that address the biological pathways concerned, or to develop companion diagnostics to ensure that new — or existing — therapies are targeted at the correct subgroup of patients.

Research in the Immunology, Microenvironment and Metastasis program is aimed at 1) merging basic mechanistic understanding of multidisciplinary pathways of host - tumor interactions and metastatic dissemination with novel translational opportunities for diseases diagnosis and immunotherapy, as well as 2) investigating mechanisms regulating immune responses in cancer and their potential therapeutic manipulation.

Dr. Peden has written or contributed to more than 160 peer - reviewed scientific publications on the kinetics and mechanisms of automobile exhaust catalysis; the development of zeolite catalysts for diesel engine emission control; hydrocarbon reforming over bimetallic catalysts; the structure of hydroprocessing catalysts; the development of novel, supported solid acid catalysts for petroleum refining; the growth and properties of oxide and semiconductor thin films; and model studies of adhesion at metal / metal - oxide interfaces.

7/17/2008 Discovery of a New Signaling Mechanism May Lead to Novel Anti-Inflammatory Therapy A team of researchers at the University of California, San Diego School of Medicine has uncovered a new signaling mechanism used to activate protein kinases that are critical for the body's inflammatory Mechanism May Lead to Novel Anti-Inflammatory Therapy A team of researchers at the University of California, San Diego School of Medicine has uncovered a new signaling mechanism used to activate protein kinases that are critical for the body's inflammatory mechanism used to activate protein kinases that are critical for the body's inflammatory response.

The prize, considered among the most prestigious in the scientific community, recognizes Schreiber for his work in chemical biology and for the use of small molecules as probes to uncover novel cellular mechanisms at the root of human health and disease.

While working with Jung at Harvard, she identified a novel molecular mechanism through which a protein in human cells called RIG - I mediates defense against viruses.

Partial copies of the extrachromosomal ribosomal DNA (rDNA) element are found at the ends of each chromosome, suggesting a novel telomere structure and the use of a common mechanism to maintain both the rDNA and chromosomal termini.

At Brandeis, Merrikh embraced the tools of molecular biology to unearth a then - novel mechanism by which bacterial cells respond to assaults on DNA.

Our current efforts are geared at understanding the mechanisms and functions of this novel concept in membrane biology, notably also using chemical biology tools to rebuild this process (synthetic biology).

«This is a significant accomplishment that reflects Avigen's strategic efforts to identify novel mechanisms to treat neurologic disorders and to protect the know - how and intellectual property of our scientific discoveries,» stated Kirk Johnson, Ph.D., Vice President of Research and Development at Avigen.

At this point, these are still novel and it is hard to incorporate effects into climate models when the physical mechanisms are not well - understood.

Over the course of the past two years, staff at the California Public Utilities Commission (CPUC) in the U.S. have introduced novel customer engagement opportunities to participate in wholesale energy markets via the Demand Response Auction Mechanism (DRAM) program.