Sentences with phrase «at an increased risk while»

Not exact matches

Important factors that could cause actual results to differ materially from those reflected in such forward - looking statements and that should be considered in evaluating our outlook include, but are not limited to, the following: 1) our ability to continue to grow our business and execute our growth strategy, including the timing, execution, and profitability of new and maturing programs; 2) our ability to perform our obligations under our new and maturing commercial, business aircraft, and military development programs, and the related recurring production; 3) our ability to accurately estimate and manage performance, cost, and revenue under our contracts, including our ability to achieve certain cost reductions with respect to the B787 program; 4) margin pressures and the potential for additional forward losses on new and maturing programs; 5) our ability to accommodate, and the cost of accommodating, announced increases in the build rates of certain aircraft; 6) the effect on aircraft demand and build rates of changing customer preferences for business aircraft, including the effect of global economic conditions on the business aircraft market and expanding conflicts or political unrest in the Middle East or Asia; 7) customer cancellations or deferrals as a result of global economic uncertainty or otherwise; 8) the effect of economic conditions in the industries and markets in which we operate in the U.S. and globally and any changes therein, including fluctuations in foreign currency exchange rates; 9) the success and timely execution of key milestones such as the receipt of necessary regulatory approvals, including our ability to obtain in a timely fashion any required regulatory or other third party approvals for the consummation of our announced acquisition of Asco, and customer adherence to their announced schedules; 10) our ability to successfully negotiate, or re-negotiate, future pricing under our supply agreements with Boeing and our other customers; 11) our ability to enter into profitable supply arrangements with additional customers; 12) the ability of all parties to satisfy their performance requirements under existing supply contracts with our two major customers, Boeing and Airbus, and other customers, and the risk of nonpayment by such customers; 13) any adverse impact on Boeing's and Airbus» production of aircraft resulting from cancellations, deferrals, or reduced orders by their customers or from labor disputes, domestic or international hostilities, or acts of terrorism; 14) any adverse impact on the demand for air travel or our operations from the outbreak of diseases or epidemic or pandemic outbreaks; 15) our ability to avoid or recover from cyber-based or other security attacks, information technology failures, or other disruptions; 16) returns on pension plan assets and the impact of future discount rate changes on pension obligations; 17) our ability to borrow additional funds or refinance debt, including our ability to obtain the debt to finance the purchase price for our announced acquisition of Asco on favorable terms or at all; 18) competition from commercial aerospace original equipment manufacturers and other aerostructures suppliers; 19) the effect of governmental laws, such as U.S. export control laws and U.S. and foreign anti-bribery laws such as the Foreign Corrupt Practices Act and the United Kingdom Bribery Act, and environmental laws and agency regulations, both in the U.S. and abroad; 20) the effect of changes in tax law, such as the effect of The Tax Cuts and Jobs Act (the «TCJA») that was enacted on December 22, 2017, and changes to the interpretations of or guidance related thereto, and the Company's ability to accurately calculate and estimate the effect of such changes; 21) any reduction in our credit ratings; 22) our dependence on our suppliers, as well as the cost and availability of raw materials and purchased components; 23) our ability to recruit and retain a critical mass of highly - skilled employees and our relationships with the unions representing many of our employees; 24) spending by the U.S. and other governments on defense; 25) the possibility that our cash flows and our credit facility may not be adequate for our additional capital needs or for payment of interest on, and principal of, our indebtedness; 26) our exposure under our revolving credit facility to higher interest payments should interest rates increase substantially; 27) the effectiveness of any interest rate hedging programs; 28) the effectiveness of our internal control over financial reporting; 29) the outcome or impact of ongoing or future litigation, claims, and regulatory actions; 30) exposure to potential product liability and warranty claims; 31) our ability to effectively assess, manage and integrate acquisitions that we pursue, including our ability to successfully integrate the Asco business and generate synergies and other cost savings; 32) our ability to consummate our announced acquisition of Asco in a timely matter while avoiding any unexpected costs, charges, expenses, adverse changes to business relationships and other business disruptions for ourselves and Asco as a result of the acquisition; 33) our ability to continue selling certain receivables through our supplier financing program; 34) the risks of doing business internationally, including fluctuations in foreign current exchange rates, impositions of tariffs or embargoes, compliance with foreign laws, and domestic and foreign government policies; and 35) our ability to complete the proposed accelerated stock repurchase plan, among other things.

While increasing debt means more spending, which is good for the U.S. economy, it also puts more Americans at risk of insolvency.

According to researchers at Texas A&M University, «a successful [sobriety] checkpoint program increases the risk of arrest (real or perceived), and influences a motorist to choose to not drive while intoxicated.

They can steadily increase their profits while concurrently minimising their risk of exposure as they invest their time in studying and mastering the limitless array of binary option trading scenarios that are now available at their fingertips.

«More families that have elderly heads are placing themselves at risk of running short of money in retirement due to their increased likelihood of holding debt while in retirement,» he concludes.

While overall wage costs remain contained at present, despite pressures in particular sectors, ongoing strength in demand would pose an increasing risk of acceleration of costs over time.

How could we have accepted the challenge and taken the increased risks while at the same time refusing to accept the enormous cost that history claimed?

Our place in the coefficient table is not at risk at present, and while we still stand a chance of finishing above THAT team in second - place, any increase in our chances of winning on Sunday I will take.

But, while it seems to show a slight increased risk associated with starting curveballs at a young age, it had far too few participants to determine such an association.

There is increased risk of getting the flu while pregnant because the immune system is not as effective at fighting off infections.

Because they still have poor head control and often experience flexion of the head while in a sitting position, infants younger than 1 month in sitting devices might be at increased risk of upper airway obstruction and oxygen desaturation.128, — , 132 In addition, there is increasing concern about injuries from falls resulting from car seats being placed on elevated surfaces.133, — , 137 An analysis of CPSC data revealed 15 suffocation deaths between 1990 and 1997 resulting from car seats overturning after being placed on a bed, mattress, or couch.136 The CPSC also warns about the suffocation hazard to infants, particularly those who are younger than 4 months, who are carried in infant sling carriers.138 When infant slings are used for carrying, it is important to ensure that the infant's head is up and above the fabric, the face is visible, and that the nose and mouth are clear of obstructions.

While all postpartum women need to be screened for depression, knowing which mommas needed pitocin for an obstetric complication will help healthcare providers identify women who may be at increased risk for postpartum depression.

Another study linked fetuses that had higher amounts of the stress hormone cortisol with lower IQ scores at 18 months, while another found that stress can lead to an increased risk of developing attention deficit hyperactivity disorder (ADHD).

THEM: * recite SOGC guidelines for induction after 41 weeks, cite data showing an increase in the risk of stillbirth after 39 weeks, particularly amongst older mothers, me with a narrow pelvis, a first - timer carrying a posterior baby estimated at 9.2 lbs, BPP / NST only a snapshot of what's happening right at that moment and while a bad BPP / NST is unequivocally a poor sign, a good BPP / NST is not always indicative of zero issues * And then they played the dead baby card.

While great progress has been achieved in recent years in preventing child occupant deaths and injuries, and increasing the correct use of child safety seats, booster seats and safety belts — thanks in no small measure to the tireless dedication of NHTSA and its many partners in the child passenger safety community — more work needs to be done to protect child occupants who remain at heightened risk.»

Cobedding of twins and other infants of multiple gestation is a frequent practice, both in the hospital setting and at home.174 However, the benefits of cobedding twins and higher - order multiples have not been established.175, — , 177 Twins and higher - order multiples are often born prematurely and with low birth weight, so they are at increased risk of SIDS.101, 102 Furthermore, there is increased potential for overheating and rebreathing while cobedding, and size discordance might increase the risk of accidental suffocation.176 Most cobedded twins are placed on their sides rather than supine.174 Finally, cobedding of twins and higher - order multiples in the hospital setting might encourage parents to continue this practice at home.176 Because the evidence for the benefits of cobedding twins and higher - order multiples is not compelling and because of the increased risk of SIDS and suffocation, the AAP believes that it is prudent to provide separate sleep areas for these infants to decrease the risk of SIDS and accidental suffocation.

We also discuss how the same underlying cultural beliefs that supported the idea that infants sleep best alone serve presently to permit the acceptance of an inappropriate set of assumptions related to explaining why some babies die unexpectedly while sleeping in their parents beds.9 These assumptions are that regardless of circumstances, including maternal motivations and / or the absence of all known bedsharing risk factors, even nonsmoking, sober, breastfeeding mothers place their infants at significantly increased risk for SUID by bedsharing.

In fact, the little data that is available on this says that infants who are in the adult be to breastfeed and are then placed back to sleep in a safe crib are not at increased risk of SIDS (those would be the infants like my babies who bedshared in adult bed accidentally because the mother did not plan or intend to bedshare but passed out while night nursing and woke up several hours later).

Proponents argue it would boost New York's natural gas supply to help keep energy costs down while creating jobs and generating tax revenue, while opponents, who rallied this month ahead of the decision, say it would increase fossil - fuel use, harm sensitive ecosystems and put the state at inordinate risk of dangerous methane leaks.

Drivers had no idea that this was going on, and while the state was collecting the money, residents were being put at increased risk of identity theft.

The medications excel at quelling hallucinations and delusions, yet largely fail to address schizophrenia's debilitating cognitive and social impairments, while increasing risk for movement disorders, weight gain, and other metabolic and cardiovascular side effects.

While tougher regulations have driven lead levels down globally since the 1990s, mercury levels in the North Pacific Ocean have increased 30 percent over the last 20 years, potentially putting humans at higher risk of exposure from seafood (See «Made in China: Our Toxic, Imported Air Pollution»).

While the Johns Hopkins team studies the likely effects of radiation on the brain during a deep space mission, other NASA - funded research groups are looking at the potential effects of radiation on other parts of the body and on whether it increases cancer risks.

Research at the time indicated the latter increased the virulence of the former when combined with each other, allowing the injections to induce the feverish effects while drastically reducing the risk of death.

«We need to be aware of the problem and prepare for it, either by vaccinating at an early age or by putting people on antiviral drugs while they're at increased risk,» says Patterson.

«While obesity at a younger age is associated with an increased risk of future dementia, obesity in people who have lived to about 60 - 80 years of age seems to be associated with a reduced risk,» they conclude.

«While IPV can impact women at any stage in the life course, research indicates that women between the ages of 18 - 24 are at increased risk.

«In this study, we show that a large increase in BMI during puberty is particularly important, while high BMI at age 8 is not linked to increased risk of cardiovascular death,» says Jenny Kindblom, associate professor at the University of Gothenburg's Sahlgrenska Academy.

While the genes themselves do not result in early onset menopause, variations of the genes — CYP3A4 * 1B and CYP1B1 * 3 — were found to increase the risk of entering menopause at an earlier age in white smokers.

While the risk of MCI increases with age overall, younger men were at a higher risk of developing MCI than younger women.

«While we can't guarantee that the partners of patients will not develop oral HPV infections or cancers, we can reassure them that our study found they had no increased prevalence of oral infections, which suggests their risk of HPV - related oral cancer remains low,» says Gypsyamber D'Souza, Ph.D., M.P.H., associate professor of epidemiology at the Johns Hopkins University Bloomberg School of Public Health.

And while human populations are largely adapted to local climates, researchers point to «an increase in mortality risk observed at both high and low temperatures in populations in temperate and cold climates... and tropical and subtropical areas.»

«Due to increasing concerns about the risks of long - term opioid therapy for chronic pain and limited evidence as to their benefit, the Centers for Disease Control and Prevention released its Guideline for Prescribing Opioids for Chronic Pain in 2016,» said Merlin, who completed this research while at the University of Alabama at Birmingham.

While this rapid response increases their likelihood of getting a good meal, it also puts them at risk of hastily misidentifying predators as parents.

Chokshi said, «in general, most individuals who increase their workouts gradually and feel well while doing so are at low risk and require no medical evaluation.

While Houston's yearly risk of experiencing a 500 - millimeter rainfall event was around 1 in 2,000 at the end of the last century, Emanuel found the city's annual odds will increase significantly, to one in 100 by the end of this century.

While dietary supplements may be advertised to promote health, a forum at the American Association for Cancer Research (AACR) Annual Meeting 2015 by University of Colorado Cancer Center investigator Tim Byers, MD, MPH, describes research showing that over-the-counter supplements may actually increase cancer risk if taken in excess of the recommended dietary amount.

Researchers have found a way to increase the effectiveness of a widely used cancer drug while decreasing the risk of heart - damaging side effects, according to a new study by researchers from The University of Texas Medical Branch at Galveston and Texas Tech University Health Sciences Center.

«While these findings require further study into the mechanism that causes shingles patients to have an increased risk of heart attack and stroke, it is important that physicians treating these patients make them aware of their increased risk,» said Sung - Han Kim, MD, PhD, a physician in the department of infectious diseases at Asan Medical Center in Seoul and one of the study authors.

As in prior studies among older adults, we found that obesity was associated with a decreased risk of dementia, consistent with the hypothesis that, while obesity in mid-life may increase risk for later - life cognitive decline and dementia, obesity at older ages may be associated with cognitive and other health advantages.25 - 27 The trend toward a declining risk for dementia in the face of a large increase in the prevalence of diabetes suggests that improvements in treatments between 2000 and 2012 may have decreased dementia risk, along with the documented declines in the incidence of common diabetes - related complications, such as heart attack, stroke, and amputations.11 Our finding of a significant decline between 2000 and 2012 of the heart disease - related OR for dementia would also be consistent with improved cardiovascular treatments leading to a decline in dementia risk.

In a study in Lebanon, exposure to passive smoking at work was associated with almost double the risk of chronic bronchitis (an 89 percent increased risk), while passive smoking at home was associated with more than two - and - a-half times the risk of chronic bronchitis.

For the hydrological modelling of the Thames river catchment done at CEH we showed that the changes in atmospheric circulation and precipitation caused higher peak 30 - day river flow, while flood risk mapping revealed a small increase in flood risk for properties in the Thames catchment.

While the exact cause is unknown, some genetic conditions, hepatitis B infection, and biliary atresia (a blockage in the ducts that carry bile) can put a child at increased risk.

We are currently exploring this further, but this result suggests that while PTEN may increase sensitivity of at - risk neurons to death, at least some neurons also require PTEN for normal function.

A potential explanation for the secular trend may be that while improved treatment for cardiovascular risk factors or complicating diseases has reduced mortality in all weight classes, the effects may have been greater at higher BMI levels than at lower BMI levels.12 Because obesity is a causal risk factor for hypertension, diabetes, cardiovascular disease, and dyslipidemia,15,19 - 22 obese individuals may have had a higher selective decrease in mortality.18 Indirect evidence of this effect is seen in the findings as the deaths occur at similar time periods in the 3 cohorts, but cohorts recruited at later periods have an increase in the BMI associated with the lowest mortality, possibly suggesting a period effect related to changes in clinical practice, such as improved treatments, or general public health status, such as decreased smoking or increased physical activity.

They noted that while most sedentary behavior — like watching television — is known to increase the risk of death, previous studies have found that reading either reduces that risk or has no effect at all.

Another respected speaker at the conference was Gary Taubes, a Harvard physicist who argued that refined carbs fuel the over-production of insulin and stimulate fat storage, while increasing the risk of heart disease, diabetes and cancer in his book The Diet Delusion, published seven years ago.

â $ While the average woman should not take a drug to reduce the risk of breast cancer,» explains Julie R. Gralow, MD, the director of breast medical oncology at the University of Washington and Fred Hutchinson Cancer Research Center in Seattle, «I would consider them for a woman whos had a biopsy that shows an increased risk for development of cancer.»

One of the biggest dangers of sleep apnea — besides the fact that it raises blood pressure and increases the risk for heart disease and diabetes — is that it can put people at risk for falling asleep behind the wheel, or while operating machinery.

While they could theoretically increase breast cancer risk, at this point the risk is just that — theoretical — «and based on animal and other lab studies,» says Janet Gray, PhD, director of science, technology and society at Vassar College in Poughkeepsie, N.Y., who researches environmental impacts on breast cancer.