Sentences with phrase «at cell division»

For instance, the laboratory has unraveled multiple roles of survivin at cell division, all of which ensure that the physical act of cell division occurs properly.

The Altieri laboratory has extensively used cell biological approaches to probe the function of survivin at cell division.

In these bacteria, the cells that are «born» at cell division can be distinguished by their poles.

Of the two different daughter cells generated by Caulobacter at each cell division only one is equipped with the capsule.

Paradoxically, the exception is at the very moment when chromosomes are most vulnerable, when they physically separate into two cells at cell division (mitosis).

Not exact matches

Most chromosomal abnormalities are the cause of a damaged egg or sperm cell or are due to a problem at the time that the zygote went through the division process.»

Too much stress suppresses glial cell division — and glial cells take care of myelinization at developmental plateaus (myelin is the capstone for a neuron and facilitates communication with other neurons).

The authors of the study referenced in the article found there was no causal connection between light and cell division in the brain of mice if they had artificial light shined at them at one - hour intervals.

Here's what they found — during cell division, UHRF1 recognizes newly copied DNA at sites that are missing methyl tags.

«When a new substance forms during a chemical reaction, many students think that the atoms and molecules have actually changed into something new, whereas they simply rearranged, that the mass increase of plants is due to minerals in the soil, or that cell division alone accounts for animal growth,» said Cari Herrmann Abell, a senior research associate at Project 2061.

At an early stage of development, the miniature organs grown from autistic patients» stem cells also showed faster cell division rates than those grown from the cells of non-autistic relatives.

The long - term persistence of CD8αα + T cells where initial infection occurs may explain why patients have asymptomatic recurrences of genital herpes because these cells constantly recognize and eliminate the virus, according to Jia Zhu, Ph.D., corresponding author, research assistant professor in Laboratory Medicine at the University of Washington and an affiliate investigator in the Fred Hutch Vaccine and Infectious Disease Division.

«We have developed a drug candidate, a next - generation biologic medical product, and are now publishing the fantastic results from the preclinical part where wound healing was strongly accelerated in mice,» says Mia Phillipson, Professor at the Department of Medical Cell Biology, Division of Integrative Physiology, Uppsala University.

«These findings stimulate new avenues for cell therapy approaches for regenerative medicine,» said Douglas Millay, PhD, study senior investigator and a scientist in the Division of Molecular Cardiovascular Biology at Cincinnati Children's.

«This research represents an important step toward the goal of being able to better treat thyroid diseases and being able to permanently rescue thyroid function through the transplantation of a patient's own engineered pluripotent stem cells,» explained co-corresponding author Anthony N. Hollenberg, MD, Chief of the Division of Endocrinology, Diabetes and Metabolism at BIDMC and Professor of Medicine at Harvard Medical School.

This complex biological machine gathers the chromosomes together and sorts them at the time of cell division, then sends them to the opposite poles of the daughter cells in a process called chromosome segregation.

The results show — for the first time, Briggs thinks — that the bacterial genomes change with depth: the micro-organisms at 554 metres carry more mutations in genes that code for energy - related processes like cell division and biosynthesis of amino acids than are seen in their shallower counterparts.

Austad recalls one conversation in which Muller made an insightful connection about telomeres, the DNA - and - protein caps at the ends of chromosomes that shorten with every cell division, eventually pushing cells into a nondividing state called senescence.

The protein puts the immune system's brakes on, keeping its T cells from recognizing and attacking cancer cells, said Dr. Antoni Ribas, the study's principal investigator and a professor of medicine in the division of hematology - oncology at the David Geffen School of Medicine at UCLA.

«Our cells may provide a substantial opportunity for the development of zero - emission vehicles with a driving range similar to that of gasoline vehicles,» says Elton Cairns, of the Environmental Energy Technologies Division (EETD) at Berkeley Lab.

After gaining a degree in molecular sciences from Wageningen University in 1991, he left the Netherlands to do his PhD on the structure of membrane protein at the Cell and Molecular Biosciences division of the University of Newcastle's medical school.

But exposure to the chemicals blocked cell division, which could lead to neurological disabilities in babies if their cells are exposed at particular times during fetal development.

But cell division was always at the back of my mind.

A combination of circumstances induced me to leave India and enroll in the graduate program in what was then the department of cellular and developmental biology at the University of Arizona, Tucson, in the U.S. My Ph.D. supervisor, Neil Mendelson, had been a well - known name in DNA replication and cell division in Bacillus subtilis, but by the time I had joined his lab, his interest had decidedly shifted to cell shape determination.

A group of scientists at Okinawa Institute of Science and Technology Graduate University (OIST) and collaborators at Stockholm University showed for the first time how this big protein complex inside living E. coli cells disassembles after each round of division.

«Why is the division of egg cells — which is so important at the start of animal life — why is that not very reliable?»

UTSW co-authors include: Co-lead author Maria Winter, a research associate; Dr. Luisella Spiga, a postdoctoral researcher; visiting fellow Lisa Büttner; graduate students Elizabeth Hughes and Caroline Gillis, all of Microbiology; Dr. Breck Duerkop, Instructor, Immunology; Cassie Behrendt, a research technician, Immunology; Dr. Lora Hooper, Professor and Chair of Immunology with appointments in Microbiology and in the Center for the Genetics of Host Defense, a HHMI Investigator and holder of the Jonathan W. Uhr, M.D. Distinguished Chair in Immunology, and the Nancy Cain and Jeffrey A. Marcus Scholar in Medical Research, in Honor of Dr. Bill S. Vowell; Dr. Luis Sifuentes - Dominguez, Instructor of Pediatrics; Dr. Kayci Huff - Hardy, clinical fellow, Internal Medicine in the Division of Digestive and Liver Diseases; Dr. Andrew Koh, Associate Professor of Pediatrics and Microbiology and in the Harold C. Simmons Comprehensive Cancer Center as well as Director of Pediatric Hematopoietic Stem Cell Transplantation at Children's Health; and Dr. Ezra Burstein, Professor of Internal Medicine and Molecular Biology and Chief of the Division of Digestive and Liver Diseases.

«Functional germ cells are special because they do not contain a double set of chromosomes and are no longer capable of division,» says Professor Christian R. Eckmann, a developmental geneticist and Heisenberg Professor at MLU.

The research team, led by senior author Timothy P. Cripe, MD, PhD, chief of the Division of Hematology / Oncology / BMT at Nationwide Children's Hospital, found that virotherapy doesn't always require a strong virus infection of cancer cells to cause tumors to shrink or die.

Ain attended the annual Endocrine Society meeting in Toronto, where Bryan Haugen, head of the endocrinology division at the University of Colorado School of Medicine, told Ain that several of his most popular cell lines were not actually thyroid cancer.

Located at the ends of chromosomes, telomeres typically shorten with each cell division, until the end of the chromosome becomes so frayed that the cell dies.

«There has been ongoing debate about whether the methylation mark can be passed on through cell divisions and across generations, and we've now shown that it is,» said corresponding author Susan Strome, a professor of molecular, cell and developmental biology at UC Santa Cruz.

During cell division, chromosomes acquire a characteristic X-shape with the two DNA molecules (sister chromatids) linked at a central «connection region» that contains highly compacted DNA.

The whole process is reminiscent of trial - and - error learning in which each cell explores — at its own rhythm and independently of cell division — different molecular possibilities (i.e. different genes turned on or off) before reaching a stable combination of active genes and the corresponding morphology.

The arithmetic is complex, but the consensus is that, to pose a health threat, cancers have to replicate at least 200 to 300 times, even though a clinically relevant tumor contains «only» a million million cells, which could be achieved by «only» 40 or so divisions if the originating cell had all the necessary mutations from the outset.

This was not known at all, and the idea that it could be a secret of cell division was so far from people's minds that nobody had ever suggested it.

Moffitt Cancer Center researchers have found that a protein called TBK1 plays an important role in the process of cell division, especially at a stage called mitosis.

Franco Folli, M.D., Ph.D., professor of medicine in the Diabetes Division of the School of Medicine at The University of Texas Health Science Center at San Antonio, is co-author on the findings presented in Cell Stem Cell.

«Our study suggests that although you need to have some level of IgE to trigger a food allergy response, you also have to produce MMC9 cells to get a severe response and anaphylaxis,» says Yui - Hsi Wang, PhD, lead investigator and a researcher in the Division of Allergy and Immunology at Cincinnati Children's.

«In other words, at that moment of cell division, the cell miss - identified its own telomeres as damaged DNA, which it then «repaired,» Dr. Orthwein says.

Paulo Navarro - Costa, first co-author of this study and researcher at the IGC explains: «Similarly to humans, fruit fly ovules also have a resting period during meiosis — the specialized cell division required for the formation of healthy reproductive cells.

«We found that expression of glucose transporters is completely shut down by bacteria, leaving insufficient fuel for the immune cells to fight off the infection,» said the study's first author, Subramanian Krishnan, PhD, of the Division of Infectious Diseases at CHLA.

Gabriela Cabral, a PhD student in the lab of Alex Dammermann at the Center for Molecular Biology of the University of Vienna, explains: «Many people thought that centrioles are held together by the same glue as chromosomes, a substance called cohesin, which is destroyed during cell division.

In a bid to progress beyond the shotgun approach to fighting cancer — blasting malignant cells with toxic chemicals or radiation, which kills surrounding healthy cells in the process — researchers at the Harvard - MIT Division of Health Sciences and Technology (HST) are using nanotechnology to develop seek - and - destroy models to zero in on and dismantle tumors without damaging nearby normal tissue.

«We found that harmine, likely by interacting with DYRK1A, increases levels of other known drivers of cell division,» said Peng Wang, PhD, Assistant Professor of Medicine, Endocrinology, Diabetes, and Bone Disease at the Icahn School of Medicine and first author of the paper.

Landry and colleagues have long been promoting the idea of getting stem cells from dead embryos, and have been scrutinizing embryos at various stages in order to develop watertight criteria for showing «irreversible arrest» of cell division.

They showed that when these cells experience warmer temperatures and get more nutrients they can double or triple their cell division rates, allowing them to potentially bloom into a large population fairly quickly at sea.

«We have immune cells called T - cells that are really good at killing off cancer cells, but there is an inhibition system in place to prevent autoimmunity,» said the study's senior author Maureen Su, MD, UNC Lineberger member and associate professor in the UNC School of Medicine Division of Pediatric Endocrinology.

Silvia Ardissone, researcher in the Department of Microbiology and Molecular Medicine at UNIGE's Faculty of Medicine, works with Caulobacter crescentus, a bacterium that shows a particularly interesting cell division.

The dense mass of the PCM that entraps the sister centrioles is itself disassembled at the end of cell division.