Sentences with phrase «at cell shapes»

«Due to the nature of how a cell nestles among its immediate neighbors, a scientist can now look at cell shapes and make a reasonable guess as to why, and how fast, those cells will migrate, remodel, or invade surrounding tissues.»

By looking at the cell shape in 3D with this approach, you can compare them.

Not exact matches

A good example of this behaviour is seen in the shape of an apple which can be explained in terms of the cells of the apple but «apple shape» has no meaning at lower levels of description.

Donald Ingber, M.D., Ph.D., Founding Director of the Wyss Institute at Harvard University, started investigating this «architecture of life» over thirty - five years ago, and discovered that Nature uses an architectural principle known as «tensegrity» (short for «tensional integrity») to stabilize the shapes of living cells and to determine how they respond to mechanical forces.

Mahmoudi and his colleagues previously identified several others overlooked biological factors that appear to contribute to discrepancies seen between results in the lab and in the clinic, including importance of personalized medicine at the nanobio interfaces, cell type, cell shape, and incubating temperature.

BRAIN CANDY A new database offers a deep look at living human nerve cells, revealing elaborate branching structures and myriad shapes, such as in this neuron called a pyramidal cell (cell image, left and 3 - D computer reconstruction, right).

Lagasse, based at Pitt's McGowan Institute for Regenerative Medicine, has discovered how to turn any one of the body's 500 lymph nodes — the small, oval - shaped organs where immune cells gather to fight invading pathogens — into an incubator that can grow an entirely new liver.

A combination of circumstances induced me to leave India and enroll in the graduate program in what was then the department of cellular and developmental biology at the University of Arizona, Tucson, in the U.S. My Ph.D. supervisor, Neil Mendelson, had been a well - known name in DNA replication and cell division in Bacillus subtilis, but by the time I had joined his lab, his interest had decidedly shifted to cell shape determination.

Liu and his team became interested in the phenomenon of Treg cell instability after earlier studies had hinted at Treg cells» shape - shifting abilities but no specific molecular mechanism ensuring their functional stability — or lack thereof — had been identified.

It's not the first attempt at artificial red blood cells, but these are the only ones so far to have the shape and elasticity of real cells, says Mitragotri.

Depending on which device they buy, researchers can photograph cells at anywhere from 20x to 60x magnification, and use the included software to sort them by purely visual characteristics such as shape and size, fluorescent markers, or both.

The 120 - foot - long, pickle - shaped prototype at Toledo Express Airport resembles a blimp: Its soft but tough skin, similar to a boat's sail, encases balloon - like cells filled with helium.

Nevertheless, as Tobias says, it is still ``... a field beset with relatively few facts but many theories... The story of early hominid brains has to be read from carefully dated, well identified, fossilised calvariae, or from endocranial casts formed within them... Such materials confine the Hercule Poirot, who would read «the little grey cells» of fossil hominids, to statements about the size, shape and surface impressions... of ancient brains...» The other major limiting factor at the moment is the lack of suitable fossil skulls for such studies.

To ensure this, Wandt developed a rod - shaped cell while he was a doctoral candidate in the group of Prof. Hubert A. Gasteiger, Chair of Technical Electrochemistry at TUM, that allows the formation of metallic lithium to be detected directly and with quantitative precision.

To do this without a brain or nervous system, says Ken Showalter, a chemist at West Virginia University, the organism relies on proteins and nutrients that «swish back and forth» through the cell to communicate the location of the food and allow the organism to change shape.

Sheldrake's basic folly, argues Wolpert, is that he is pushing the notion of morphic resonance at precisely the time when strictly biochemical analysis of cell structure and organization is close to providing a comprehensive explanation for morphogenesis, the process by which living creatures acquire their shapes.

While researchers at the Georgia Institute of Technology don't have a specific application for the doughnut - shaped droplets yet, they believe the novel structures offer opportunities to study many interesting problems, from looking at the properties of ordered materials within these confined spaces to studying how geometry affects how cells behave.

As a maximum number of target cells is to contact the array, a fishbone - shaped structure at the top of the channel stirs up the passing liquid.

New research at Rice University suggests actin filaments that control the shape of neuron cells may also be the key to the molecular machinery that forms and stores long - term memories.

To get a better grasp on the problem, bioengineer Christopher Chen and colleagues at the Johns Hopkins University School of Medicine in Baltimore played with the shape of growing stem cells.

If you rub your eyes too much, you send random, meaningless noise to your brain, and all the cells for all the shapes begin screaming at once.

It is Neuroscience 101 that neurons pass on electrochemical messages at communication sites called synapses, but it is less well appreciated that the vast majority of synapses are «tripartite,» consisting not just of a neuron sending a message and one receiving it, but also, nestled alongside each synapse, a star - shaped glial cell called an astrocyte.

Eggan has been working with Steve McCarroll, associate professor of genetics at Harvard Medical School and director of genetics at the Stanley Center, to study how genes shape the biology of neurons, which can be derived from these stem cells.

Physicists of Ludwig - Maximilians - Universitaet (LMU) in Munich now show that, at high concentrations, a crucial protein can assemble into ring - shaped filaments that constrict the cell, giving rise to two daughter cells.

«Our findings indicate the existence of long - distance interactions between lung tumors and bones: lung tumors remotely activate osteoblasts, and those bone cells, in turn, shape immunity by supplying tumors with cancer - promoting neutrophils,» says Pittet, who is an associate professor of Radiology at Harvard Medical School.

Some of these clusters form at the cell poles, the rounded ends of rod - shaped bacteria like Escherichia coli.

In a new study being presented at The Allied Genetics Conference in Orlando, Florida, researchers report new insights about the underlying drivers that help cells heal and maintain their shape.

On the surface of our numerous star - shaped brain cells called astrocytes, they have found the molecule LRP4 is important in ensuring healthy levels of a brain chemical that enables learning and memory, said Dr. Lin Mei, chairman of the Department of Neuroscience and Regenerative Medicine at the Medical College of Georgia at Augusta University and Georgia Research Alliance Eminent Scholar in Neuroscience.

Alexander Graham Bell (far right) strung tetrahedral cells into a range of star - and ring - shaped kites and flew them at his Cape Breton Island estate in the early 1900s.

A hole stays open at the bottom of the cell until the larva nears pupation from her fat grub shape into a queen with wings.

«I'm interested in understanding how single cells maintain their proper shape,» said Athena Lin, graduate student at the University of California, San Francisco, and lead researcher on the project.

«We look at the cell's shape, size and texture as well as its surface biochemistry,» Goda explains.

«By changing the surface properties like the shape of the substrate at the nanoscale level, we tricked the stem cells to behave differently,» explains co-author Dr Julien Gautrot, from QMUL's School of Engineering and Materials Science and the Institute of Bioengineering.

Now, a team from Keio University in Japan, working with a researcher at Imperial College London, have discovered that the shape of the epidermal cells combined with their ability to temporarily glue together, may explain how they form this strong barrier.

To help design new structures that enable cells to «shape up,» researchers at the National Institute of Standards and Technology (NIST) have come up with a way to measure, and more importantly, classify, the shapes cells tend to take in different environments.

(Bottom) Plotting the characteristic ellipsoids for each cell by how round they are in the two major cross sections reveals that cells tend to different shapes on different scaffolds — spheres at one extreme, long narrow rods at another.

In a study published in Molecular Cell this month, Alexei V. Tulin, PhD, Associate Professor at Fox Chase Cancer Center, and colleagues reported that chemical modification of one type of histone — called H2Av — leads to substantial changes in nucleosome shape.

Responding to the TGF - β produced by its own cells, the developing tubule can apparently sense where it has the most room to grow away from itself — for example, at the narrow ends of a rectangle or the tips of a Y - shaped well.

William Ratcliff, a biologist at the Georgia Institute of Technology in Atlanta, and his collaborators have discovered a surprisingly simple route to multicellularity: a single mutation in yeast that adheres the mother cell to its daughter to create a snowflake - like shape.

The CBM now forms the core of the new Kavli Institute at Trondheim, which was inaugurated in August 2007 and where research continues on grid cells, as well as areas such as understanding the role of the hippocampus in shaping memory.

Methods: The team profiled lipids using analytical chemistry techniques and monitored changes in cell shape using capabilities in the Quiet Wing at EMSL, a Department of Energy national scientific user facility located at PNNL.

If ACT will succeed at this stage and will able to show long - term safety, it will shape and determine the future development and commercialization of embryonic stem cell - based products.

In 1973, a research team headed by Ralph Steinman at the Rockefeller University also described a new immune cell type, which they called the dendritic cell for its branching, tree - like shape.

For the first time, scientists know what happens to a virus» shape when it invades a host cell, thanks to an experiment by researchers at Penn State College of Medicine and University of Pittsburgh School of Medicine.

This visualization shows tightly - packed DNA in a mouse cell's nucleus at different stages of development, seen here in a semi-triangular form as a mature nerve cell; in a roundish shape as a multipotent stem cell; in a more oval form as a neuronal progenitor; and as a more fragmented structure that shows how removing a specialized binding protein (HP1β knockout) affects the structure of the DNA - packing material, called heterochromatin, in a mature neuron.

Mark did his postdoctoral work with Dr. Lewis Lanier at the University of California, San Francisco, where he researched the response of natural killer (NK) cells to viral infection, studying both the signaling pathways and educational programs that shape NK cell responses to infection in vivo.

Specific topics include the abilities to recognize, sort and transport important molecules; sense the environment; alter shape or surface texture; generate onboard energy to power effective robotic functions; communicate with doctors, patients, and other nanorobots; navigate throughout the human body; manipulate microscopic objects and move about inside a human body; and timekeep, perform computations, disable living cells and viruses, and operate at various pressures and temperatures.

A team at the University of Leeds has discovered that shaping gold nanoparticles in the form of minuscule tubes sees them take on a number of new properties, including the ability to be heated up to destroy cancer cells.

The Wnts in turn trigger a cascade of shape - making decisions that guide cells to take specific shapes, like curved eyelid cells or vibrating hair cells in the ear, and even make sure that arms and legs emerge at the right spots.

If you've been working relentlessly at developing your midsection and cutting down body fat, but there's still no sign of your abs» true shape and definition — you could be storing subcutaneous fluid in your cells that creates a bloated look and prevents your hard - earned muscles from fully appearing on the surface.