Sentences with phrase «at crossing the blood brain barrier»

As will be reported at the upcoming FSMA - sponsored 11th Annual International SMA Group Meeting in June, our compounds prolong survival in mouse models of SMA and are very effective at crossing the blood brain barrier to reach motor neurons in the spinal cord.

Not exact matches

It offers cardio protection, it helps lower bad cholesterol, it may help prevent the progression of multiple sclerosis, it has the ability to regenerate brain cells after a stroke, it has the ability to cross the blood - brain barrier to potentially ward off Alzheimer's disease, apparently it's good at wiping amyloid plaque from the brain (which studies haves linked to Alzheimer's), it may help to prevent certain types of cancer, and studies have shown that it inhibits cancer cell growth and metastases (meaning it keeps cancer from spreading).

«Few drugs have the capacity to cross the tumor blood - brain barrier and specifically target tumor cells,» says principal investigator Balveen Kaur, PhD, associate professor of neurological surgery and chief of the Dardinger Laboratory of Neurosciences at the OSUCCC — James.

An experimental drug in early development for aggressive brain tumors can cross the blood - brain tumor barrier, kill tumor cells and block the growth of tumor blood vessels, according to a study led by researchers at the Ohio State University Comprehensive Cancer Center — Arthur G. James Cancer Hospital and Richard J. Solove Research Institute (OSUCCC — James).

Today in Angewandte Chemie, scientists at the Institute for Research in Biomedicine (IRB Barcelona) have presented a shuttle able to cross the blood - brain barrier and transport various substances into the brain.

«Crossing the blood - brain barrier is a rare event in part because this structure is designed to protect the brain from pathogens,» said Christopher Hunter, the Mindy Halikman Heyer President's Distinguished Professor at Penn Vet.

A team led by principal investigator Donald M. O'Rourke, MD, an associate professor of Neurosurgery at Penn, and Marcela Maus, MD, PhD, showed that CART - EGFRvIII cells had an acceptable safety profile, crossed the blood - brain barrier, infiltrated the tumor, and prompted an immune response, resulting in reduction of the EGFRvIII tumor antigen in GBM cells.

Researchers from the U.S. Military HIV Research Program at the Walter Reed Army Institute of Research (WRAIR) have found that an experimental heroin vaccine induced antibodies that prevented the drug from crossing the blood - brain barrier in mice and rats.

We are also exploring how intranasal vasopressin, which crosses the blood brain barrier in humans, influences subjective responses to faces in men and women and, through a collaboration with James Rilling at Emory University, how vasopressin modulates brain responses to those stimuli.

After only two such rounds of injection and amplification, a handful of variants emerged as those that were best at crossing the blood - brain barrier and entering astrocytes.

Researches from St. Louis and Japan (Banks A, Coon AB, Robinson SM, Moinuddin A, Shultz JM, Nakaoke R, Morley JE, et all, Triglycerides induce leptin resistance at the blood - brain barrier) found that leptin's ability to cross the blood brain barrier is interrupted by triglycerides (fats found in the blood stream).

Thus, it is possible that the CNS abnormalities observed in ME / CFS patients can be explained, at least in part, by the ability of leptin and resistin to cross and / or disrupt the blood — brain barrier (46).