Sentences with phrase «at doses»

Our data support recent findings that higher doses of olanzapine (> 10 mg / d) are associated with greater metabolic abnormalities.12 While data for risperidone were inconclusive, 12 our data suggest a dose - response relationship at doses higher than 1.5 mg / d.

He creates the impression that white asbestos is safe at all doses.

Remember that at doses this low, the hormesis people are claiming health benefits.

After a one - time administration of Advil to dogs, signs of irritation or damage to the GI tract are seen at doses as low as 25 milligrams per kilogram (mg / kg).

At the ASPCA Animal Poison Control Center we become concerned with naïve dogs who are exposed to trazodone at 5 mg / kg, though mild signs can be seen at doses lower than that.

A developmental neurotoxicity screening study in rats suggests that imidacloprid may also cause neurotoxicity in offspring born to imidacloprid - exposed mothers at doses which do not cause maternal toxicity.»

Some dogs have a mutation that impairs this system and inhibits removal of this drug, and others, from the body and predisposes them to toxicity issues at doses normally not expected to be problematic.

At these doses the drug can also increase friendly and interactive behavior.

Repeated use of ibuprofen will increase the risk of toxicity even at doses that would not be toxic in single exposures.

In most cases this treatment is safe and effective but some individuals have a mutation (of the MDR1 gene) which makes ivermectin very toxic at the doses used to kill mites.

For dogs, neurologic signs may be seen at doses 400 mg / kg and higher; ferrets, however, are particularly prone to developing neurologic signs and may do so at much lower doses than dogs.

In most cases this treatment is safe and effective but some individuals have a mutation which makes ivermectin very toxic at the doses used to kill mites.

In fact at the doses used, the chemotherapy is not having direct cytotoxic activity, i.e. not directly killing the cancer cells.

During initial testing spinosad was given to pregnant and nursing mother dogs at doses slightly above the recommended dose.

In most cases this treatment is safe and effective but some individuals have a mutation that makes ivermectin toxic at the doses used to kill mites.

At doses superior to 40 mg / kg of body weight cardiac signs develop, including increased heart rate, high blood pressure and cardiac arrhythmia.

Cats are much more sensitive to the effects of the toxicity, and experience toxicity at doses as low as 1.5 mL per kilogram.

Capilano claims Beeotic may benefit digestive health and improve overall health and immunity at doses of 14 ml per day.

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Using this approach, researchers have extensively studied alcohol's effects in healthy people at doses ranging from 0.16 to 1.0 grams of alcohol per kilogram of body weight (g / kg)(Williams and Salamy 1972).

However, at doses above 1 g / day, absorption falls to less than 50 % and absorbed, unmetabolized ascorbic acid is excreted in the urine [4].

Exposure of rats, mice, and dogs for several weeks showed some damage to the testes and sperm at doses of more than 26 mg boron / kg which corresponds to 15 grams of borax / day for 60 kg body weight.

I think the same is basically true of supplementing iodine at doses sufficient to remediate deficiency of this most critical nutrient.

L - leucine, administered orally during organogenesis at doses up to 1000 mg / kg body weight, did not affect the outcome of pregnancy and did not cause fetotoxicity in rats.

They opted for higher doses of pramlintide (240 ug TID [three times per day]-RRB- because in dose - escalation studies, the incidence and severity of adverse drug reactions was consistently low at all doses tested.

Systematic reviews and meta - analyses of prospective cohort studies assessing the relationship between legumes, which include dietary pulses, and the risk of CHD at doses & 4 weekly 100 - g servings provide moderate - quality evidence of a benefit.

Dietary pulses at doses of 120 — 132 g / day (0.5 — 0.75 cups / day, the equivalent of about one serving / day) have shown meaningful reductions in established cardiometabolic risk factors, including HbA1c, LDL - C, body weight, and blood pressure, with the evi - dence for these specific reductions ranging from low to moderate quality.

Six human trials have demonstrated that curcumin in particular, a diferuloylmethane in turmeric, elicits significant anti-inflammatory activity, and is safe at doses up to 8000 mg (8 grams) a day for up to three months with no toxicity (Chainani, 2003).

They report that the side effects of iodine, including hypo - or hyperthyroidism, allergies, swelling of the salivary glands and thyroid, occur in less than 5 percent.21 Urine tests confirm that iodine at these doses removes the toxic halogens fluoride and bromide from the body.22

According to these physicians, iodine at these doses does indeed reverse fibrocystic disease; allows diabetic patients to use less insulin and hypothyroid patients to use less thyroid medication; resolves symptoms of fibromyalgia; and stops migraine headaches.

In addition, this same study noted that turmeric has been found to be pharmacologically safe, with no toxicity noted at doses up to 10 grams per day.

With both the rat studies, the mother rats consumed RRL right from the start of their pregnancies, at doses much higher than what humans ingest in a cup of tea.

It is effective as a thyroid suppressor at doses of 0.9 - 4.2 mg per day for hyperthyroidism.

At no point are prescription appetite suppressants recommended to be taken at doses above 250 mg per day.

Thiamine supplements are usually taken at doses between 50 mg and 100 mg.

Patients were on a stable dose of dopamine agonist (ropinirole, mean 8 mg / day or pramipexole, mean 1.5 mg / day) therapy for ≥ 30 days, but at doses not sufficient to control Parkinson's disease symptoms.

For example, vitamin C becomes an antioxidant at doses above 600 mg, while the RDA is only 60 mg, one - tenth of that.

At doses of 750 mg / day, vitamin C has been shown to raise progesterone in women with both low progesterone and luteal phase defect.2 Henmi H., et al. «Effects of ascorbic acid supplementation on serum progesterone levels in patients with a luteal phase defect.»

At doses higher than the immune modulation doses, it is shown to reduce the body's set point and cause significant weight loss.

In light of this, one research team found that curcumin did, in fact, produce impressive increases in serotonin and noradrenaline levels when administered at doses of 10 mg per kilogram of body weight.

However, there have been a few case reports of individuals who developed sensory neuropathies at doses of less than 500 mg daily over a period of months.

Sensory neuropathy typically develops at doses of pyridoxine in excess of 1,000 mg per day.

There is a potential for side effects at those doses.

Second, Warfarin, a vitamin K inhibitor, produces a toxicity profile almost identical to that of vitamin D, but does not increase serum calcium levels.81 Third, one group used vitamin D to produce calcium deposition in the kidneys of chickens at doses that did not lead to hypercalcemia.104 This finding is consistent with a case report of four post-menopausal women who were taking undetermined doses of vitamin D without their knowledge in the form of supplements that appeared to be contaminated with large amounts of vitamin D2: these patients had abnormally high vitamin D levels, three times the calcium in their urine as is normal, and appeared, albeit inconclusively, to have associated bone loss.

Since vitamin K1 is preferentially delivered to the liver rather than to other tissues, this may be why vitamin K1 at doses found in the diet offers little if any protection against cancer.

One trial of progesterone cream at various doses showed no change in hot flashes — this time using progesterone cream at doses of 60, 40,

This essential vitamin is water soluble and generally considered safe at doses up to 2,000 mg a day, according to the Mayo Clinic.

At doses larger than that, it can potentially be problematic.

A minimum dose of 200 mcg was required to reduce TPO antibodies in clinical trials (100mcg did not have an effect), and selenium can be toxic at doses > 800mcg.

Fluoride is effective as a thyroid suppressor at doses of 0.9 - 4.2 mg per day for hyperthyroidism.