Sentences with phrase «at doses lower»

At the ASPCA Animal Poison Control Center we become concerned with naïve dogs who are exposed to trazodone at 5 mg / kg, though mild signs can be seen at doses lower than that.

Remember that at doses this low, the hormesis people are claiming health benefits.

Not exact matches

Separately, a Food and Drug Administration panel recommended that an experimental rheumatoid arthritis drug developed by Lilly and Incyte should only be approved at a lower dose.

There are some toxins, such as alcohol, that your body can deal with at a low level and that will kill you only at high doses.

They had never really before tried to limit the negative effects of low interest rates — asset - price bubbles — while at the same time as applying a heavy dose of monetary stimulus.

At an FDA advisory panel meeting in October 2016 to discuss appropriate naloxone dosing, Seamus Mulligan, chief executive of Adapt Pharma Inc., said that «lower doses of naloxone may deliver too little naloxone, too late.»

An up - close look at a new way of taking medicine: a matchstick - size device that when implanted under the skin releases a steady, continuous, and low - dose stream of medicine.

BERLIN German dialysis specialist Fresenius Medical Care cut its 2018 sales target due to lower than expected doses of calcimimetic drugs at its dialysis service business in the United States.

Many of these effects are found at very low, physiologically relevant doses.

â $ cents Results from the studies reviewed suggest that some patients exhibit symptoms at much lower doses of gluten than others.

Ramsey did very well in the euro and it showed he is better in the middle I think he is too afraid because if his broken leg or his confidence is low because he is susceptible to big mistakes and at times he seems weak Why is that I don't know but I know from watching him that he is a very good player dose he suit in the wings?

To that end some doctors will advise taking a single low dose immediately at the onset of anxiety and panic symptoms.

The drug also reduced their testosterone levels at both low and high doses.

Widespread concern and public pressure — combined with growing science on arsenic's toxicity at low doses — should have spurred the U.S. Food and Drug Administration (FDA) and the cereal industry to take high - arsenic cereals off store shelves.

In these instances, choose the lowest dose possible and hold off on starting the pill until at least 4 to 6 weeks postpartum when breastfeeding is well established.

Diagnostic Radiology at Boston Children's is designed to facilitate high - quality and rapid x-ray examinations using the lowest possible radiation doses for your child, no matter her size, age or medical condition.

Epidural analgesia associated with low - dose oxytocin augmentation increases cesarean births: a critical look at the external validity of randomized trials.

Unfortunately you failed to report the results of the most definitive research on BPA, which found no evidence of health effect at low doses, or the conclusion from the NTP review.

Of the studies that have been done, one or more studies show reproductive effects at very low doses, organ system toxicity, and developmental / reproductive toxicity!

Because there are no standard dosages based on a child's weight, stimulants are usually started at a low dosage and gradually increased to find a child's best dose, which «is the one that leads to optimal effects with minimal side effects.»

The phytoestrogen can act like estrogen at low doses but block estrogen at high doses.

Chemicals having estrogenic activity (EA) reportedly cause many adverse health effects, especially at low doses in babies and children.

This would help tamp down antibiotic resistance, while allowing doctors to lower the dosage of antibiotics that are toxic at high doses and that produce nasty side effects such as deafness and kidney damage.

«The median percentage reduction in seizure frequency was more than 29 percent for patients on a low - dose regimen of everolimus and nearly 40 percent for patients with high - dose regimen to the drug,» says David Franz, MD, founding director of the TSC Clinic at Cincinnati Children's Hospital Medical Center and the study's senior author.

They are now developing newer generations of the compound that are more potent at lower doses.

At low doses of cocaine, the GAPDH in the nucleus will stimulate the neuron, but at higher doses it activates the cell's self - destruct pathwaAt low doses of cocaine, the GAPDH in the nucleus will stimulate the neuron, but at higher doses it activates the cell's self - destruct pathwaat higher doses it activates the cell's self - destruct pathway.

«Although there was an overall dampening effect of alcohol on the prefrontal cortex, even at a low dose of alcohol we observed a significant positive relationship between dorsomedial and dorsolateral prefrontal cortex activity and alcohol - related aggression,» explains Denson.

The low dose required for infectivity and the severity of the disease it causes had led the Centers for Disease Control and Prevention to classify F. tularensis as a Category A bioterrorism agent, and to track tularemia cases nationwide, according to Dr. Brook Peterson, a senior scientist at the UW School of Medicine who also participated in the study.

These antianxiety drugs «are known to be safe, and we are using them at very low levels here,» study author Scheuer notes, adding he is not concerned about human patients receiving low doses of antianxiety drugs off - label.

Abiraterone's ability to lower levels of prostate - specific antigen, a surrogate marker for prostate cancer, was slightly greater for patients in the low - dose with food group when measured at 12 weeks.

At lower doses, it temporarily produces the same schizophrenia - like effects as PCP.

Frequent, low - dose chemotherapy regimens avoid this effect and may therefore be more effective at treating certain types of breast and pancreatic cancer, according to the murine study «Metronomic chemotherapy prevents therapy - induced stromal activation and induction of tumor - initiating cells,» which will be published online November 23 in The Journal of Experimental Medicine.

A separate review by Ducharme and a different group of colleagues looked at 22 studies that tested varying the dose of steroids, and found that lower doses had less of an effect on height.

At a 0.2 - millimolar sucralose dose similar to the concentration found in the blood of people with high consumption of low - calorie sweeteners — equal to four cans of diet soda per day — the researchers said they observed increased expression of genes that are markers of fat production and inflammation.

«Our preclinical data suggest that combining low doses of these inhibitors will enhance the clinical effects of both drugs as a potential treatment for patients with AML,» says the senior author, Feyruz V. Rassool, PhD, associate professor of radiation oncology at the University of Maryland School of Medicine (UM SOM) and a researcher at the University of Maryland Marlene and Stewart Greenebaum Comprehensive Cancer Center (UMGCCC).

«Our stem cell - based studies indicate that low - calorie sweeteners promote additional fat accumulation within cells compared with cells not exposed to these substances, in a dose - dependent fashion — meaning that as the dose of sucralose is increased more cells showed increased fat droplet accumulation,» said Sabyasachi Sen, M.D., Associate Professor of Medicine at George Washington University in Washington, D.C. «This most likely occurs by increasing glucose entry into cells through increased activity of genes called glucose transporters.»

The researchers found that at lower densities, the populations took longer to return to previous levels after being shocked with a dose of salt — which can harm or kill yeast — in their growth medium.

Low - dose and high - dose OIT were safe and equally effective at suppressing allergic immune responses to peanut, investigators found.

Michael Oshinsky at Thomas Jefferson University in Philadelphia, Pennsylvania, and colleagues tested the effect of low doses of ethanol — about the equivalent of a single drink — on rats prone to migraines.

It can be used to wean addicts off their drug of choice, and then is either discontinued or continued at a lower, maintenance dose.

People are increasingly taking daily, low doses of illegal psychedelic drugs to up their game at work and improve their mood.

Either way, taking antimalarials at low doses, for a short period, is a surefire way to generate resistance.

At high sugar doses, the small intestine couldn't keep up: The vein connecting the intestine and liver had a much higher ratio of fructose to glucose than at lower sugar doseAt high sugar doses, the small intestine couldn't keep up: The vein connecting the intestine and liver had a much higher ratio of fructose to glucose than at lower sugar doseat lower sugar doses.

At lower sugar doses, researchers found metabolites from labeled fructose molecules abundant in the small intestine, and only small amounts in the liver and in the vein that connects the small intestine to the liver.

The effect is most severe at lower doses, according to new research, including concentrations similar to what might be found in the environment.

This venom affects insects and mice at lower doses than prevenom, the team reports online this week in the Proceedings of the National Academy of Sciences.

«Not only that, but in testing two doses of rivaroxaban, we found that we have the option of lowering the daily dose for extended treatment,» said Dr. Jeffrey Weitz, principal investigator of the study and professor of medicine and biochemistry and biomedical sciences at the Michael G. DeGroote School of Medicine at McMaster University.

The response we've seen in flies to low doses of lithium is very encouraging and our next step is to look at targeting GSK - 3 in more complex animals with the aim of eventually developing a drug regime to test in humans.

The average litter size was reduced by 10 % to 20 % at all doses compared with controls, but it was most reduced at low doses.

In this prospective birth cohort study, researchers looked at the effects of low - dose chemical exposure in 164 pregnant women.