Sentences with phrase «at doses up»

L - leucine, administered orally during organogenesis at doses up to 1000 mg / kg body weight, did not affect the outcome of pregnancy and did not cause fetotoxicity in rats.

Six human trials have demonstrated that curcumin in particular, a diferuloylmethane in turmeric, elicits significant anti-inflammatory activity, and is safe at doses up to 8000 mg (8 grams) a day for up to three months with no toxicity (Chainani, 2003).

In addition, this same study noted that turmeric has been found to be pharmacologically safe, with no toxicity noted at doses up to 10 grams per day.

This essential vitamin is water soluble and generally considered safe at doses up to 2,000 mg a day, according to the Mayo Clinic.

Five weeks prior to initiating pembrolizumab, patients were given intralesional T - VEC injection at doses up to 4 mL per treatment (106 PFU / mL, then 108 PFU / mL every 2 weeks).

All six of them quickly fell seriously ill with multiple organ trauma, even though the stuff had worked well on rabbits and monkeys at doses up to 500 times as large.

Animal studies of the chemical have found it has no health effects on reproduction or development at doses up to at least 100 mg per kg of body - weight per day.

Not exact matches

An up - close look at a new way of taking medicine: a matchstick - size device that when implanted under the skin releases a steady, continuous, and low - dose stream of medicine.

New patients must take their daily dose at a dedicated clinic, racking up single «take - home» doses over months and years of satisfactory urinalysis results that signify they aren't taking other drugs.

Greg, Again, you were doing just fine giving praise to the Creator YHWH up until you start giving His praise to another, this dose not please the King YHWH, not none at all.

The raucous soul of Nathaniel Fisher has roamed at will through the four seasons of the series since his demise, delivering up doses of wisdom and wry humor, happily haunting the places and the people he loved.

Greens like kale, collard greens, turnip greens, Swiss chard, and mustard greens give you a healthy dose of calcium plus that important vitamin K. Eat your greens outside, and you can soak up some vitamin D at the same time!

«I had seen an earlier galley of Simply Vibrant, but I didn't know how much I needed this dose of inspiration until the physical book showed up at my door.

3 months is looked at per minimum it take more than six months for a bone to heal some very minor muscle will take 3 months a serious injury which takes 8 months and more + rehabilitation while a player is rehabilitating other injuries my form a direct result of being constrained where muscles freeze you are not playing for 8 months you cant expect the muscles to be up and running straight away players how ever want to play because of all sort of reasons one being replaced so it hampers with their full recovery hence having players regularly in the treating room but take it from me some times you are perfect you just get back bang someone heavy dose your ankle in so you are back in out off playing time I personally got very angry because my knee was ok so went back out to come back in after one game with ankle problem after a couple of weeks i will go back out I have no guarantees that some one wouldn't go heavy on me or me injuring myself going heavy on someone else its football thats the way it is if it is not a medallion for the cabinet its a leg medallion

There is no excuse there Mr wenger said it in his press conference» repeated mistakes» has no excuse partying till 3:30 at the morning just before a game is a decrease and shows contempt Unless Mr Wnger takes the bull by the horn and fixes the problems at hand immediately or face a spiral to the bottom hope though it dose not end up in panic buys but rather intelligent buys and sorting out our internal problems He has been in football for 35 years so in essence the experience should bale him out with a good fix h

Betting market: Clemson opened as 5 - point favorites at Pinnacle, and a heavy dose of public and sharp support has pushed it up to -10.

If New Zealand parents wish their baby to receive oral vitamin K, the recommended regimen is for 3 x 1 mg doses, 1 at birth, 1 at 5 days and 1 at 6 weeks.6, 20 It is up to parents to ensure that their baby receives all 3 doses if they choose this form of prophylaxis.

However, lessons were learned from these early programmes and in 2004, the Texas Fragile Families initiative reported an increase in child support orders / paternity establishment among its participants (with a «dose» effect — the longer the young father was involved in the programme, the more likely he was to establish paternity / pay child support); and employment rates up from 50 % at the start of the programme to almost 70 % at six months and 80 % at one year (Romo et al, 2004).

They involve numerous doses of food at 15 minute intervals, often beginning in the early morning and lasting for up to 6 hours.

These babies need follow up tests and further doses of vaccine against hepatitis B virus at one month, two months and twelve months of age for full protection.

If I were delivering in the hospital they would already know what was going on, which would save at least 15 - 20 minutes by eliminating both the transportation and the evaluation / explanation parts of the process, and I would probably already have an epidural so all they would have to do to operate is up the dose a notch.

If you develop a clog then you can up your dose at that time.

She may turn out to be Cuomo's secret weapon on the campaign trail, as she proved to be a natural at mingling with New Yorkers who lined up to get a hot lunch and a dose of celebrity.

Voters could turn on the government for alleged shortcomings in its precautionary planning, although Labour could claim that the need to buy up 30m doses of Tamiflu highlights the weaknesses in the «Google health» approach to medicine outlined by David Cameron in his speech to the Tory spring conference at the weekend.

We have estimated that up to 15 percent of patients will be candidates for dose optimization,» explained senior study author Javier F.Torres - Roca, MD, director of Clinical Research and associate member of the Department of Radiation Oncology at Moffitt.

In all environments and independent of the resource settings, two doses of human papillomavirus vaccine are recommended for girls ages 9 to 14 years, with an interval of at least 6 months and up to 12 to 15 months between doses.

«Short - term increases in inhaled steroid doses do not prevent asthma flare - ups in children: Findings challenge common practice of increasing doses at early signs of worsening symptoms.»

Based on the results of a pilot study at MGH that evaluated doses as high as 40 grams, participants in the current study received doses of up to 30 grams daily.

People are increasingly taking daily, low doses of illegal psychedelic drugs to up their game at work and improve their mood.

At high sugar doses, the small intestine couldn't keep up: The vein connecting the intestine and liver had a much higher ratio of fructose to glucose than at lower sugar doseAt high sugar doses, the small intestine couldn't keep up: The vein connecting the intestine and liver had a much higher ratio of fructose to glucose than at lower sugar doseat lower sugar doses.

They trip each other up, which prevents the axons from fully extending through the brain and delivering the usual doses of serotonin, says Tom Maniatis, a study coauthor and molecular neuroscientist at Columbia University.

By that I mean you can take 10 estrogenic chemicals at doses that on their own don't have an effect, but if you add them together, you end up with problems.

Following an initial phase in which the dose of the drug was gradually increased in patients, 72 patients enrolled in the second phase, in which two doses were tested at different administration schedules — weekly, twice monthly, and monthly — for up to two years.

These eels will throw up to 600 volts at over seven or eight amps — that's quite a dose of electricity.

Philip Laipis of the University of Florida, who has also observed tumors in AAV vector - treated mice, agrees, at least for studies using a similarly high dose of AAV to target liver cells, which are more likely than other cell types to take up the AAV vector.

In some cases, patients» tumors develop resistance to Gleevec — either the Abl protein mutates so that the drug can no longer bind to it, or the protein accumulates in such quantities that the drug can't keep up, even at the highest dose.

So I grew up with a comfortable dose of biology, at least enough to arouse my intellect.

University of Tübingen researchers in collaboration with the biotech company Sanaria Inc. have demonstrated in a clinical trial that a new vaccine for malaria called Sanaria ® PfSPZ - CVac has been up to 100 percent effective when assessed at 10 weeks after last dose of vaccine.

Muir Woods National Monument, CA Marvel at the redwoods — renowned as the tallest trees in the world — but also take a moment to taste the clover - shaped redwood sorrel that makes up much of the ground cover and has a surprisingly citrusy flavor (though it's toxic in large doses).

All 1127 patients at the hospital were kept heavily sedated for up to 14 days with massive doses of tranquillisers and barbiturates.

They were followed up one day after the first dose, and then at 1, 2, 3, and 5 weeks and 3 months after the second dose.

«We found that intensive doses of statins carry the potential for clearing up the lipid debris that can lead to vision impairment in a subset of patients with macular degeneration,» said Joan W. Miller, M.D., the Henry Willard Williams Professor and Chair of Ophthalmology at Harvard Medical School and Chief of Ophthalmology at Massachusetts Eye and Ear and Massachusetts General Hospital.

Part of the problem is that trials involving vitamin D and calcium are inconsistent — they test different doses for varying lengths of time in diverse populations, which «makes it extra tricky when you try to put them all together and come up with a final analysis,» says Erin LeBlanc, an endocrinologist at the Kaiser Permanente Center for Health Research in Portland, Ore..

«This study, one of only a few large studies to have follow - up beyond five years, demonstrates that patients who have head and neck cancers and who are being treated with radiation therapy alone have improved local - regional control and no increase in late toxicity when radiation therapy is delivered twice a day in two smaller doses which we call hyperfractionation,» said Jonathan J. Beitler, MD, MBA, FASTRO, lead author of the study and professor of radiation oncology, otolaryngology and hematology / medical oncology at the Winship Cancer Institute of Emory University School of Medicine in Atlanta.

Changes in BNP were not correlated with mean heart dose on day 1, the final day of treatment, or at the first follow - up.

Biomarker measurements were taken before RT, within 24 hours of the first dose, on the day of the last dose, and at first follow - up 1 - 2 months after completion of RT..

The authors suggest that for the future «A more complete clinical analysis should entail follow - up for at least 2 or 3 years and with an increased dose range; such a design presumably would reveal the impact of dose on both acute and late RT - related toxicity and thereby strengthen the associations observed in this analysis of acute effects.»

Stuck's team waited until their subjects had entered the REM phase of sleep, the stage at which most dreams occur, and then exposed them to a high dose of smelly air for 10 seconds before waking them up one minute later.

In the present study, we provide evidence that inhibition of the RARs at a very low daily dose (1.0 mg / kg) for a treatment period of up to 16 weeks consistently produced male sterility that was reversible upon cessation of the treatment.

Under a special allowance from the Nuclear and Industrial Safety Agency, workers at Fukushima were permitted doses of up to 250 millisieverts.