Furthermore, the membrane microdomains induced by BAR domains are expected to function as diffusion barriers, which may for example trap membrane - associated receptor and cargo molecules
at the endocytic bud.
Amphiphysin isoforms have a putative role in membrane deformation
at endocytic sites.
Not exact matches
WAFL, a new protein involved in regulation of early
endocytic transport
at the intersection of actin and microtubule dynamics.
Using automated high - content superresolution imaging and quantitative data analysis, we determined how more than a dozen
endocytic proteins are organised
at the nanoscale.
A host of
endocytic processes has been described
at the plasma membrane of eukaryotic cells.
We now aim
at unraveling molecular and functional links between
endocytic sorting
at the plasma membrane and retrograde sorting on early endosomes.
In the
Endocytic Trafficking and Intracellular Delivery team we study the cell biology of carbohydrate - binding proteins (lectins)
at the level of cellular entry though clathrin - independent endocytosis, retrograde sorting on early endosomes, and translocation to the cytosol.
Our group has discovered two protein - protein interaction networks that sit
at the heart of numerous
endocytic and trafficking processes: the EH (Eps15 Homology) and monoUb networks (9 - 13).