Not exact matches
However, a study performed
at Edinburgh University found that much of our predisposition toward determination, sociability, self -
control, and sense of purpose is in our
genes.
What all these have in common is that, without any central
control, individual units (
genes, cells neurons or workers) respond to simple, local information, in ways that allow the whole system (cells, brains, organisms or colonies) to function: the appropriate number of units performs each activity
at the appropriate time.
«We actually do have
control over our
genes, which can be exciting and daunting
at the same time.
The reliability and stability of these methods were described by Wu et al. 27 Illumina tag sequencing of the 16S rRNA
gene V4 - V5 hypervariable region was performed
at the Marine Biological Laboratory in Woods Hole, Massachusetts, using established methods.28, 29 Details of sequencing methods, quality
control and filtering, and statistical modeling are presented in the eAppendix in the Supplement.
The feeding tube of the dying embryos was not forming properly, so researchers
at first speculated that the
gene controlled tube development.
At least 20 different
genes control lycopene production.
To receive funding from Safe
Genes, teams focused on
gene - drive technology must work on
controls plus
at least one of the program's other focus areas — remediation or inhibitors.
Psychiatrist Ming Tsuang and his colleagues
at Boston University figured that if
genes help
control what people feel when they smoke pot, then genetically identical twins should experience a similar kind of high or low when they use the drug.
At the same time, Asahina stresses, finding a
gene that influences aggression does not mean that aggression is
controlled only by
genes and always genetically programmed.
DNA methylation is a mechanism cells use to
control gene expression
at the epigenetic level.
Kevin Esvelt, head of the Sculpting Evolution lab
at MIT Media Lab, which is applying for Safe
Genes funding in collaboration with eight other research groups, predicts that eventually, perhaps around 15 years from now, an accident will allow a drive with potential to spread globally to escape laboratory
controls.
However, last August a team headed by plant ecologist Allison Snow
at Ohio State University demonstrated that this same
gene might produce some very tough weeds: She found that wild sunflowers crossed with Bt sunflowers produced offspring that suffered significantly less insect - related damage and produced 50 percent more seeds than
control plants without the
gene.
«I'm very relieved,» says Andrea Crisanti, a molecular parasitologist
at Imperial College London, who is part of an effort that seeks to use
gene drives to
control malaria.
The team also found that two clusters of these
genes control different kinds of aggression: one directed
at strangers and strange dogs, and the other directed
at the owner and other dogs in the household.
Gene drives are just the latest attempt
at biological
control systems.
The researchers also looked
at the expression of a
gene involved in the
control of wing development, and found similarity between the lab - induced supersoldiers and the natural ones.
Since beginning a lab dedicated to understanding cancer metastasis
at Rockefeller six years ago, Associate Professor Sohail Tavazoie has found that microRNAs — tiny strands of RNA that function as switches to inactivate specific
genes — play an important role in
controlling genes linked to metastasis.
«Our study provides compelling evidence that the fetus regulates the timing of its birth, and that this
control occurs after these two
gene regulatory proteins − SRC - 1 and SRC - 2 − increase the production of surfactant components, surfactant protein A and platelet activating factor,» said senior author Dr. Carole Mendelson, Professor of Biochemistry, and Obstetrics and Gynecology
at UT Southwestern.
Researchers working in the Development and Growth
Control Lab
at IRB Barcelona reveal that the Dpp
gene (BMP in humans) plays a double role in the structural organisation and growth of the wings of the fruit fly Drosophila melanogaster.
Research coordinated by Osaka University has now shown that the nuclear protein complex cohesin must be expressed
at sufficient levels in the early mouse brain to
control gene regulation and allow development of healthy neuronal networks and behavioral characteristics.
Now, using computer simulations, James Carothers and his colleagues
at JBEI have sped up the RNA design phase, creating computer tools that will help researchers design molecules to precisely
control gene expression in bacteria to optimize fuel production.
Gene Robinson, a geneticist
at the University of Illinois
at Urbana - Champaign, says that the paper «opens a new line of study on the role of epigenetics in
controlling reproductive conflict» in bumblebees.
«As a result of the previous study, we reported that SUMO is probably important for
controlling expression of active
genes because we found it on every
gene we looked
at, but only when they were turned on,» notes Rosonina.
Using an innovative crystallization technique for studying three - dimensional structures of
gene transcription machinery, an international team of researchers, led by scientists
at Penn State, has revealed new insights into the long debated action of the «magic spot» — a molecule that
controls gene expression in Eschericahia coli and many other bacteria when the bacteria are stressed.
First, looking
at a study of 185 cases of childhood epilepsy, Wittkowski's team found that mutations in
genes that
control axonal guidance and calcium signaling — both of which are important early in the developing brain when neurons are forming the appropriate connections — led to increased chances of having the disorder.
«
Genes previously linked to schizophrenia seem to be dependent on the
controlled release of dopamine
at specific locations in the brain.
To further identify the role of TAZ, the research team studied breast tissue
at different stages of development using two groups of mice: a
control group with the TAZ
gene and an experimental group of knock - out mice with the TAZ
gene deleted.
The ability to retain salt —
controlled in part by a
gene called CYP3A5 — varies by latitude, according to geneticists
at the University of Chicago.
Based on previous work, the researchers had reason to think it was
controlled by transcription factors — proteins that
control the expression of certain
genes by binding to DNA
at specific locations to induce (or block) the transcription of information from DNA to RNA.
Now, Darnell's team reports that FMRP sits
at the top of a protein manufacturing plant - actually supervising the production of proteins that
control genes.
The nanotechnology approach that is being tested for inhibitor
control could also improve the haemophilia treatment that is now
at the cutting edge of clinical research:
gene therapy.
Scientists of the Transfaculty Research Platform «Molecular and Cognitive Neurosciences» (MCN)
at the University of Basel and the Psychiatric University Clinics have now described a network of
genes that
controls fundamental properties of neurons and is related to working memory, brain activity and schizophrenia.
Each cell of our body is the result of an orchestra of sophisticated mechanisms that
control which
genes are and are not expressed
at any given time.
Scientists
at NYU Langone Medical Center and New York University have demonstrated that a specialized DNA - binding protein called CTCF is essential for the precise expression of
genes that
control the body plan of a developing embryo.
Believing that science and medicine are inextricably linked, he decided to do a PhD
at the MRC Mill Hill laboratories and investigated the role of regulatory elements in
controlling gene expression, graduating in 1996.
Jones, 62, is an expert in transcription elongation, a process that
controls the expression of HIV and cancer
genes; she has been
at the Salk since 1986.
The
gene that
controls shell thickness, creatively named SHELL, was identified in 2013 by researchers
at Orion, Cold Spring Harbor Laboratory in New York and the Malaysian Palm Oil Board (MPOB), a government research institute based near Kuala Lumpur.
«
At the LMB, you can approach big questions, like how is
gene expression
controlled?»
Thus, this cDNA derives from a
gene (oct - 2) that specifies an octamer binding protein expressed preferentially in B lymphocytes, proving that, for
at least one
gene, a cell - specific transcription factor exists and its amount is
controlled through messenger RNA availability.
P. falciparum is a top target of
gene sequencers because it has thwarted all attempts
at control.
And Dr. Ludovic Orlando from the Centre for GeoGenetics
at the University of Copenhagen concludes: «Perhaps even more exciting as it represents the hallmark of animal domestication, we identify
genes controlling animal behavior and the response to fear.
Dr Kat Arney, science communication manager
at Cancer Research UK, said: «Only a tiny fraction of our DNA contains actual
genes, and we know that
at least some of the bits in between — often dismissed as «junk» — play important roles in
controlling how
genes get switched on and off
at the right time and in the right place.
Another important pathway, related to the p53
gene (a protector of the genome), is also relevant when we looked
at gene expression in the skin of acne twins compared to twin
controls.»
In C. amylolentus, dozens of
genes at two different locations on the chromosomes
control what's called a tetrapolar, or four - part, mating system.
At the cellular level, the clock is
controlled by a complex network of
genes and proteins that switch each other on and off based on cues from their environment.
Peter Meyer, a molecular biologist
at the University of Leeds, and his colleagues identified a
gene they labeled Sho (for shooting), which
controls production of cytokinins, hormones that delay aging in plants.
«We have to build a large enough study to be able to look
at both
genes and environment together,» says Newschaffer, who is a principal investigator on a study by the Centers for Disease
Control that will look
at 2,700 children over the next five years.
«Clock
genes»
control our circadian rhythms, and the easiest place to extract evidence of their activity is from hair follicles, according to researchers
at Japan's Yamaguchi University.
Increasingly local adaptation to climate is being studied
at the molecular level by identifying which
genes control climate adaptation and how these vary between individuals.
Associate Professor Amanda Sainsbury - Salis expressed surprise
at the impact of the Y6
gene deletion on mice, commenting «I find it amazing that one
gene, which is expressed in the small part of the brain that
controls the body clock, has such a profound impact on how much fat is stored on the body, and how much lean tissue is maintained.»