Sentences with phrase «at high genetic risk»

In a birth cohort study, risk of psychosis in adulthood was raised by a factor of 4 if the mother, during pregnancy, reported that a baby was unwanted.49 Separation from parents in early life has been found to predict an increased risk of psychosis in genetically vulnerable children, 50,51 and the association between immigrant status and severe mental illness may be at least partially explained by the high rates of early separation in migrant populations.52 Adolescents at high genetic risk of psychosis have also been found to be at increased risk of psychosis in later life if they report adverse relationships with their parents.53

This is especially likely to be the case if, in the absence of well - developed ToM skills, the individual is unable to attribute the negative actions of others to situational factors.137 (Consistent with this part of this model, a genetic high - risk study has reported that, in adolescents at high genetic risk of psychosis, an external locus of control predicted the later development of illness.142) These characteristics will, in turn, lead to a tendency to anticipate social threats and hence paranoid beliefs.

Assessing the usefulness of a novel MRI - based breast density estimation algorithm in a cohort of women at high genetic risk of breast cancer: the UK MARIBS study

A study led by Massachusetts General Hospital investigators has found that, even among those at high genetic risk for heart disease, following a healthy lifestyle can cut in half the probability of a heart attack or similar event.

About 30 percent of cases involved risk - reducing mastectomy in women at high genetic risk of breast cancer.

Researchers used accelerometers to measure the daily physical activity of participants, all of whom are in late middle - age and at high genetic risk for Alzheimer's disease, but presently show no cognitive impairment.

Of all four groups studied, only those at high genetic risk for Alzheimer's who did not exercise experienced a decrease in hippocampal volume (3 %) over the 18 - month period.

Those at higher genetic risk developed asthma earlier in life than did those with lower risk.

The researchers found strong evidence that people with higher genetic risk for several mental disorders — including schizophrenia, and to a lesser extent bipolar and major depressive disorder — are also at higher genetic risk for developing PTSD after a traumatic event.

«Following a healthy lifestyle can greatly reduce genetic heart attack risk: Even among those at highest genetic risk, lifestyle factors can reduce incidence by one half.»

«This work highlights the importance of severe environmental stressors in the development of suicide attempts in those at higher genetic risk for bipolar disorder.»

Not exact matches

Genetic meaning that maybe she has a personal history of mental illness or a family history of mental illness, she might be at higher biological risk because she might be an older mother, maybe has gone through infertility, pregnancy loss maybe she has multiples.

However, this study only included kids at high - risk for celiac (based on genetic markers or a first - degree relative with the disease), so it might not apply to the general population.

«The type of inflammation seen in psoriasis is known to promote insulin resistance, and psoriasis and diabetes share similar genetic mutations suggesting a biological basis for the connection between the two conditions we found in our study,» said the study's senior author Joel M. Gelfand, MD MSCE, a professor of Dermatology and Epidemiology at Penn. «We know psoriasis is linked to higher rates of diabetes, but this is the first study to specifically examine how the severity of the disease affects a patient's risk.»

Genetic alterations that can be modulated by stress have been identified in children at high risk for bipolar disorder, according to a recently published study by researchers at McGovern Medical School at The University of Texas Health Science Center at Houston (UTHealth).

The clinic monitors people who are already at high risk of pancreatic cancer due to family history or having known risk - raising genetic mutations.

According to the paper, this is one of the first times an oral biologic has been used successfully to change the natural history of a genetic disease; in this case, a mutation that puts individuals at very high risk for colon cancer.

«We believe that individuals born with this genetic mutation and who are later exposed to MAP through consuming contaminated milk or meat from infected cattle are at a higher risk of developing rheumatoid arthritis,» Naser said.

Spotting the bits of mutant DNA that underlie Alzheimer's may soon lead to genetic tests that can tell whether someone is at higher risk so he or she can take preventive steps.

At the other extreme, a high - risk release would be an indigenous weed containing a genetic implant that is not well understood.

Led by Brenda Penninx, PhD, of the VU University Medical Center in Amsterdam, the Netherlands, the study found that patients with an early age at onset and higher symptom severity have an increased genetic risk for MDD, bipolar disorder and schizophrenia.

Women with a family history of two or more immediate family members (mother, sister, daughter) with breast or ovarian cancer or with a positive genetic test for mutations in the BRCA1 or BRCA2 genes may be advised to consider having both breasts removed, because they are at high risk of a new cancer developing in the other breast.

«This test will help to determine whether an individual is at high risk of developing liver fibrosis, or whether a patient's liver disease will progress rapidly or slowly, based on their genetic makeup.

People who identify as African American, for example, are as a group at higher risk for disorders that do have a genetic component, such as hypertension and diabetes.

Should the results be confirmed by further studies, it is possible that patients with certain genetic changes in BRCA1 could be identified as being at higher risk of breast and ovarian cancer.

A test based on the genetic make - up of the Barrett's lesions could benefit patients through improved diagnosis, giving people at high risk of cancer the best care, and reducing the burden of endoscopy for those at low risk.

The results validated a previous group's discovery that measurement of the genetic diversity between Barrett's cells in any given lesion is a good predictor of which patients are at high risk of developing cancer.

«This study demonstrates that a high - risk social environment can overwhelm the protective effect of a genetic variant associated with alcohol - related behaviors,» said Emily Olfson, an MD - PhD student at Washington University School of Medicine as well as first author of this study.

Across all three prospective studies, a higher genetic risk score significantly increased the incidence of coronary events — as much as 90 percent in those at highest risk.

«Now, using a genetic approach, researchers at the University of Leicester undertaking the study on behalf of an international consortium of scientists (the CADIoGRAM + C4D consortium) have shown that the association between shorter height and higher risk of coronary heart disease is a primary relationship and is not due to confounding factors.»

Each of the genetic variants studied by the researchers is a single - nucleotide polymorphism, or SNP — a site at which the DNA code is altered by a single «letter» or nucleotide in some individuals, and where one «letter» is more commonly found in individuals with higher fracture risk.

«Increased meat consumption, especially when cooked at high temperatures, linked to elevated kidney cancer risk: Individuals with certain genetic variations more vulnerable to dietary risk.»

«If we can identify similar genetic loci in people, and if we could find biomarkers for these gene - environment interactions, then perhaps we could develop a simple blood test that identifies people who are at high risk of cancer from low - dose radiation,» says Mao.

HOUSTON --(May 8, 2017)-- Genetic alterations that can be modulated by stress have been identified in children at high risk for bipolar disorder, according to a recently published study by researchers at McGovern Medical School at The University of Texas Health Science Center at Houston (UTHealth).

Similar issues could arise from the ability to identify people at a higher risk for contracting or spreading a disease using human genetic markers.

To be certain that adoptees at high - genetic risk did not have an effect on their families as to increase dysfunction, the proportion of the families» levels of dysfunction between the low - genetic risk and high - genetic risk adoptee families were compared, and there were no significant differences found.

The key factor: Nearly half of the patients considered at high risk for recurrence might actually be low risk based on genetic factors, researchers found.

The first is that the Finnish national database that was consulted for sampling purposes is so extensive that they were able to find adoptees and families at high - and low - genetic risk for schizophrenia - spectrum disorders that were matched on demographic variables (age, education, income level, household size, etc.).

«a new genetic test to market to help determine if a person is at high risk of developing schizophrenia.»

She and her team of genetic counselors help families understand their risks for developing cancer, and provide risk - reduction strategies for those at high risk.

«It is worrisome to see so many of these women at highest risk for mutations failing even to have a visit focused on genetic counseling.»

A Lousiville, Kentucky newspaper reported this week that a company is working on bringing a new genetic test to market to help determine if a person is at high risk of developing schizophrenia.

Doctors often fail to recommend genetic testing for breast - cancer patients, even those who are at high risk for mutations linked to ovarian and other cancers, according to a study published Tuesday.

At NYU Langone's Perlmutter Cancer Center, our High - Risk Cancer Genetics Program team works together to determine a person's risk for developing cancer and to provide genetic counselRisk Cancer Genetics Program team works together to determine a person's risk for developing cancer and to provide genetic counselrisk for developing cancer and to provide genetic counseling.

The researchers examined the relationship between a risk score based on multiple genetic differences and early - onset heart disease and found that the polygenic risk score predicted a high risk for early - onset disease in one in 53 people at the same level as FH does.

Melanie Swan did not panic upon learning she had inherited a genetic mutation that seemed to put her at a higher risk of heart attack and cardiovascular disease.

Our High - Risk Cancer Genetics Program provides risk assessments and evaluations for people who may be at risk for cancer due to an inherited or genetic predispositRisk Cancer Genetics Program provides risk assessments and evaluations for people who may be at risk for cancer due to an inherited or genetic predispositrisk assessments and evaluations for people who may be at risk for cancer due to an inherited or genetic predispositrisk for cancer due to an inherited or genetic predisposition.

Presentations included: Genetics Primer & Clinical Updates by Linford Williams, MS, LGC; Genetics and Women's Health: Seeing and Foreseeing the Ethical Challenges Ahead by Ruth Farrell, MD, MA; Preimplantation Genetic Screening and Diagnosis: What You Need to Know by Marissa Coleridge, MS, LGC; Evolution of Prenatal Genetic Screening and Testing: NIPT and Beyond by Jeff Chapa, MD, MBA; Promises and Pitfalls of Prenatal Whole Exome Sequencing by Amanda Kalan, MD; Fertility Preservation and Cancer: Survivors, Previvors, and the Newly Diagnosed by Rebecca Flyckt, MD; Improving Access to Cancer Genetics via Telegenetics by Ryan Noss, MS, LGC; Breast Cancer: Management of Moderate Penetrance Predisposition Genes by Holly Pederson, MD; Use of Hormonal and Non-hormonal Therapies in Breast Cancer Survivors and Women at High Risk for Breast / Gyn Cancers by Holly Thacker, MD; Addressing Commonly Asked Patient Questions about Genetics by Rebekah Moore, MS, LGC, Christina Rigelsky, MS, LGC and Allison Schreiber, MS, LGC; and a panel discussion on Genetic Testing Reimbursement featuring Bruce Rogen, MD, MPH and John Yao, MD, MBA, MPH, which was moderated by Daniel Sullivan, MD..

The information suggests the protective effect of being reared in a healthy adoptive family, with the risk for these high - genetic - risk adoptees developing schizophrenia in healthy families at 5.8 % compared with 36.8 % for those reared in «dysfunctional» families.

A more recent interest concerns infants and children at high risk for developing autism (such as those with an older sibling with autism or who have a particular genetic variance).