Sentences with phrase «at higher dosages»

The sponsor's drug is given at a higher dosage than the competitor's drug.

Paradoxically, at high dosage levels IVIG can suppress, rather than enhance the immune response and is used to treat several inflammatory and autoimmune conditions.

Also, the relationship «did not occur at the lowest dosage range but did occur at higher dosages used long - term,» said one expert, Dr. Alan Manevitz, a clinical psychiatrist at Lenox Hill Hospital in New York City.

«Not all cases of dry AMD are the exactly the same, and our findings suggest that if statins are going to help, they will be most effective when prescribed at high dosages in patients with an accumulation of soft, lipid material» said Demetrios Vavvas, M.D., Ph.D., a clinician scientist at Mass..

Taking larger amounts isn't recommended due to potentially harmful side effects that can occur at high dosages.

One question, Wolk says, is whether the beneficial effect of alcohol that seemed to disappear at higher dosages does so suddenly, tails off or simply flattens out.

The small amounts bit is key, because at high dosages, guar gum can damage your esophagus.

However, in addition to those short term symptoms shared with marijuana alcohol use leads to other, far more sever, harmful effects increased risk taking at low dosage and death at high dosage meaning it's far more lethal to the user in the short term.

Ashwagandha can cause stomach upset in some users, particularly at high dosages.

4) Post-exercise (within 30 minutes) consumption of CHO at high dosages (8 — 10 g CHO / kg / day) have been shown to stimulate muscle glycogen re-synthesis, while adding PRO (0.2 g — 0.5 g PRO / kg / day) to CHO at a ratio of 3 — 4:1 (CHO: PRO) may further enhance glycogen re-synthesis.

These minor discomforts appear at higher dosages only, so you should start slowly and work your way up

The fuel system cleaner additive at the highest dosage rate will clean your injectors if they are dirty.

Dosage of 3 Gy per fraction are well tolerated and do not appear to be associated with significant delayed reactions such as brain necrosis that can be seen at higher dosages.

Regeneration of seminiferous tubules has been reported eight weeks after treatment with 5 % concentrations of CaCl2, but not at higher dosages [5].

However, at higher dosages used for dogs already infected with heartworm, these breeds may be more susceptible to side effects.

The authors of the EBioMedicine paper hypothesized that, due to the heterogeneous nature of the disease, patients with soft, lipid - rich drusen may respond better to statins prescribed at higher dosages.

We chose the most premium ingredients available and put them at the highest dosage levels we know are appropriate.

Unlike lecithin, the taste neutrality of Palsgaard ® AMP 4455 lets you use it at high dosages with applications sensitive to off - flavors such as crumb chocolate with its low content of cocoa solids, white chocolate, or white confectionary spreads.

The trouble with this is that at higher dosages, it can be toxic to the heart.

Interestingly, our data revealed that at a higher dosage (2 μg / well), the wild - type DDX3 and mutant DDX3 / AAA up - regulated the activity of p21waf1 / cip1 promoter ∼ 12-fold whereas the DDX3 / DQAD mutant only activated the p21waf1 / cip1 promoter activity ∼ 5-fold (Supplementary Fig.

Taking D - chiro - inositol alone, at high dosages, can adversely affect egg quality leading experts to warn against its use without screening for insulin resistance first (Vitagliano and Quaranta 201546).

Administration of DCI alone, at high dosage, can negatively affects oocyte quality, so don't go self - prescribing this treatment (Isabella and Raffone 2012).

At higher dosages they tend to cause sedation.

Cushing's disease occurs when a dog's body makes too much of the hormone cortisol or when corticosteroid medications are prescribed at a high dosage and / or for an extended period of time.

At high dosages, GI disturbances (e.g., vomiting, diarrhea) may be seen.