Luscombe, J. Ule (2010) iCLIP reveals the function of hnRNP particles in splicing
at individual nucleotide resolution.
Not exact matches
The research team's hunt for such age - related genetic associations involved studying more than 8 million single
nucleotide polymorphisms — changes of one
nucleotide for another
at a particular spot in the DNA — in 2,693
individuals.
Each of the genetic variants studied by the researchers is a single -
nucleotide polymorphism, or SNP — a site
at which the DNA code is altered by a single «letter» or
nucleotide in some
individuals, and where one «letter» is more commonly found in
individuals with higher fracture risk.
A single DNA sequence is formed from a chain of four
nucleotide bases and if some
individuals in a population do not carry the same
nucleotide at a specific position in the sequence, the variation is classified as an SNP.
At the highest level of resolution, the user can inspect the
nucleotide sequence of
individual genes.