Sentences with phrase «at lymphoma cells»

Not exact matches

«There is an unmet need to develop new therapies based on R - CHOP to try to increase the cure rate for diffuse large B - cell lymphoma,» says Patrick Johnston, M.D., Ph.D., a hematologist at Mayo Clinic and lead author.

Lymphomas are caused by an abnormal proliferation of white blood cells and can occur at any age.

The team, which included members of the Health Science Center departments of medicine and biochemistry, investigators from the UT Southwestern Medical Center at Dallas and a group of collaborators from Austria, found that the gene that codes the enzyme D2 - hydroxyglutarate dehydrogenase (D2HGDH) is mutated in a subset of cancers called diffuse large B - cell lymphomas.

«We've known about these cells blocking immune response for a decade, but haven't been able to shut them down for lack of an identified target,» said the paper's senior author, Larry Kwak, M.D., Ph.D., chair of Lymphoma / Myeloma and director of the Center for Cancer Immunology Research at The University of Texas MD Anderson Cancer Center.

A few have also developed cutaneous T - cell lymphoma at the site of old mustard burns.

The scientists at Leiden University Medical Center (LUMC) have shown that immune system cells, which react to gluten, produce chemicals called cytokines that can contribute to the development of a rare form of lymphoma (cancer of the white blood cells).

The FDA granted approval to Yescarta ™ (axicabtagene ciloleucel, Kite / Gilead) for the treatment of adult patients with several types of non-Hogdkin large B cell lymphoma that is refractory or has relapsed after at least two previous systemic treatments.

We also looked at gene expression in B - cell lymphomas, comparing samples from individuals with risk or non-risk haplotypes.

A specialist in leukemia, lymphoma, and blood and marrow transplantation, Dr. Collins leads the Hematologic Malignancies / Blood and Marrow Transplantation Program and the combined Adult / Pediatric Stem Cell Transplant Program at UT Southwestern Medical Center.

Brentuximab vedotin was previously approved by the FDA to treat cHL after relapse, cHL after stem cell transplant when a patient is at a high risk of relapse or progression, systemic anaplastic large cell lymphoma (ALCL) after failure of other treatment, and primary cutaneous ALCL after failure of other treatment.

Dumler was only the second patient at MD Anderson and the third in the world to receive CAR T cells to treat non-Hodgkin's lymphoma on the multicenter clinical trial.

More than 20 years ago Munson McLeod underwent a successful stem cell transplant to conquer his non-Hodgkin lymphoma by a caring, dedicated team at Rutgers Cancer Institute of New Jersey and Robert Wood Johnson University Hospital.

In the study, researchers at Case Western Reserve University School of Medicine gave mice mega-doses of bexarotene, a drug used to treat a type of skin cancer called cutaneous T - cell lymphoma.

One key weapon against cancer is to supercharge T - cells — the foot - soldiers of the immune system — to better detect and kill tumors, and a new trial at the Children's Research Institute has delivered promising results, keeping cases of Hodgkin's lymphoma at bay for years at a time.

CAR T cell therapies targeting CD19 for lymphoma are currently being tested in clinical trials at various institutions:

Ibrutinib is also approved to treat chronic lymphocytic leukemia / small lymphocytic lymphoma, including patients with 17p deletion, mantle cell lymphoma after at least one prior therapy, and patients with Waldenstrom macroglobulinemia.

One specific form of this approach, called chimeric antigen receptor (CAR) T cell therapy, has been shown in early clinical trials to be particularly effective at treating lymphoma.

One key technique is to supercharge T - cells — the foot - soldiers of the immune system — to better detect and kill tumors, and a new trial at the Children's Research Institute has delivered promising results, keeping cases of Hodgkin's lymphoma at bay for years at a time.

Cancer researcher Carlo Croce, M.D., who worked at Wistar from 1970 to 1988 and held the position of associate director from 1980 to 1988, cloned and characterized the B - Cell lymphoma (BCL2) gene in 1985, defining its role in various lymphomas.

On February 1st, after my first day at my new job, I was diagnosed with Lymphoma (anaplastic large cell alk negative; one of the rarer types of non-Hodgkin's lyLymphoma (anaplastic large cell alk negative; one of the rarer types of non-Hodgkin's lymphomalymphoma).

At this visit, no lymphoma cells were detected.

It's important to classify a patient with lymphoma classified into T or B cell, which can be done easily by a fine needle aspiration cytology flow cytometry at Colorado.

Finally, Hannibal's tumor sample made it to Breen's lab at NC State, where a genomic test and pathology report confirmed a diagnosis of T cell lymphoma.