Sentences with phrase «at necrosis»

Not exact matches

The approach halts further necrosis and can save a baby's life, but it often leaves infants with insufficient intestine and puts them at risk for long - term complications, such as short bowel syndrome, which requires feeding support for life due to the intestines» decreased ability to absorb enough nutrients.

Researchers at NYU School of Medicine found that the value of the drug infliximab, marketed as Remicade, in both applications proceeds from its ability to block the contribution of the protein tumor - necrosis factor alpha, or TNF alpha, to problem - causing inflammation.

One project that AquaGen started up in 2005 was a collaboration with the Centre for Integrative Genetics (CIGENE), at the Norwegian University of Life Sciences, and the Norwegian Institute of Food, Fisheries and Aquaculture Research (Nofima) to make a precise map of the genetic markers that make certain salmon individuals resistant to the IPN (infectious pancreatic necrosis) virus.

Tumor necrosis factor inhibitor drugs (commonly called Anti-TNFs) modestly reduce the risk of acute coronary syndrome, such as heart attacks and angina, in rheumatoid arthritis patients whose inflammation places them at higher risk of developing coronary heart disease, according to new research findings presented this week at the American College of Rheumatology Annual Meeting in San Diego.

Researchers led by David Wallach of the Weizmann Institute of Science in Rehovot looked more closely at a receptor called p55, which binds to a suicide - promoting cytokine called tumour necrosis factor (TNF).

At the same time, other switches get flipped throughout the body, modifying everything from metabolism to cell growth, via other cytokines, such as IL - 6 and tumor necrosis factor — a, and things like CRP, which mark bacteria for destruction.

These human astrocytes apparently did so, the scientists suggest, by secreting a protein called tumor necrosis factor - α, which mouse astrocytes produce at much lower levels.

At the cellular level, L - arginine administration resulted in acinar cell necrosis in both WNIN / Gr - Ob and control rats.

The tick feeding site shows ulceration at the location of hypostome penetration with mixed neutrophilic / eosinophilic / histiocytic inflammation and necrosis extending into the deep dermis accompanied by disorganization of the collagen bundles (Panel D).

Paracetamol is an over-the-counter drug that is toxic in high dosages, At 4g per day, hepatic necrosis may occur.

The release of inflammatory cytokines, or intercellular signaling molecules such as interleukin - 1 (IL - 1), interleukin - 2 (IL - 6), and tumor necrosis factor alpha (TNF - α) at the site of immune activation causes other immune cells migrating throughout the lymphatic vessels of the body to express more cell adhesion molecules (CAMs).

They looked at three different inflammatory markers: tumor necrosis factor, interleukin 6, and C - reactive protein.

For example, KBs were recently reported to act as neuroprotective agents by raising ATP levels and reducing the production of reactive oxygen species in neurological tissues, 80 together with increased mitochondrial biogenesis, which may help to enhance the regulation of synaptic function.80 Moreover, the increased synthesis of polyunsaturated fatty acids stimulated by a KD may have a role in the regulation of neuronal membrane excitability: it has been demonstrated, for example, that polyunsaturated fatty acids modulate the excitability of neurons by blocking voltage-gated sodium channels.81 Another possibility is that by reducing glucose metabolism, ketogenic diets may activate anticonvulsant mechanisms, as has been reported in a rat model.82 In addition, caloric restriction per se has been suggested to exert neuroprotective effects, including improved mitochondrial function, decreased oxidative stress and apoptosis, and inhibition of proinflammatory mediators, such as the cytokines tumour necrosis factor - α and interleukins.83 Although promising data have been collected (see below), at the present time the real clinical benefits of ketogenic diets in most neurological diseases remain largely speculative and uncertain, with the significant exception of its use in the treatment of convulsion diseases.

More discussion on this important study can be found at: Tumor necrosis factor in colitis — bad actor or hero?

Dosage of 3 Gy per fraction are well tolerated and do not appear to be associated with significant delayed reactions such as brain necrosis that can be seen at higher dosages.

Tumor necrosis factor - alpha at presentation in 60 cases of spontaneous canine acute pancreatitis.

Breed specific chronic hepatitis is the inflammation and possible necrosis of the liver due at least in part to a breed predisposition for developing this disorder.

Dogs that ingest greater than 0.1 g / kg of xylitol are at risk of developing low blood sugar, and dogs ingesting greater than 0.5 g / kg are at risk for acute hepatic necrosis (liver failure).

Liver cell destruction (hepatocellular necrosis), ingestion of toxic products, tainted foods or medications (such as giving Tylenol to cats, medications at too high a dose or a unique reaction to a medication that your veterinarian could not have predicted), lack of liver blood supply (hepatic hypoxia), congestive heart failure and bile duct obstruction can all cause elevated GDH levels in your pet.

«If a simple method can be developed that acts to enhance the natural processes of dentine restoration by stimulating tertiary dentine formation, then large injuries that would certainly lead the dental pulp to undergo necrosis could be repaired by enabling reparative dentine to be formed at the site of damage.»

Complications can also occur following an amputation, including joint problems, bruising, wound opening, healing problems, infection, necrosis at the site of the amputation, and occasionally the need for additional surgery.

Plasma IL - 6 and tumor necrosis factor α (TNF - α) levels and chamber - fluid IL - 6, TNF - α, and IL - 1β levels were assayed using Quantikine High Sensitivity Immunoassay kits (R&D Systems, Minneapolis, Minn), per kit instructions, as described elsewhere.47 Samples were run undiluted in duplicate, and all samples for a couple were run at the same time.

Production of IL - 6 (A), tumor necrosis factor α (TNF - α)(B), and IL - 1β (C) was lower in the blister chambers at wound sites following the marital conflict task than after the social support task.