These studies only looked at a single copy part of individuals» genomes and never
at ribosomal DNA.
Not exact matches
Crystal structures of the 30S
ribosomal subunit in complex with messenger RNA and cognate transfer RNA in the A site, both in the presence and absence of the antibiotic paromomycin, have been solved
at between 3.1 and 3.3 angstroms resolution.
The nascent chain was extended within the exit tunnel, making contacts with
ribosomal components
at distinct sites.
«We infected mice with Giardia, sacrificed them
at different times post-infection, and sequenced specific regions throughout the entire gastrointestinal tract using high - throughput 16S
ribosomal RNA sequencing,» said Dawson.
Of the 80
ribosomal proteins examined, 31 changed protein levels in
at least one cell type, Barna said.
First author Baoshan Xu, Ph.D., a former postdoctoral research associate in the Gerton Lab now starting his own lab
at Sun Yat - sen University in China, worked with Hua Li, Ph.D., to use computational methods to count the number of copies of
ribosomal DNA in normal and cancer cells of 162 patients from the eight projects.
Therefore, Teitell's group opted to further modify their constructs with a 3 ′ - UTR mitochondrial targeting sequence (MTS) from human mitochondrial
ribosomal protein S12 — the same essential approach used to optimize the import of allotopically - expressed proteins by Dr. Marisol Corral - Debrinski, (3,4) and subsequently advanced for multiple additional ETS subunit proteins by Dr. Matthew O'Connor's group
at the SENS Foundation Research Center (RC).
Partial copies of the extrachromosomal
ribosomal DNA (rDNA) element are found
at the ends of each chromosome, suggesting a novel telomere structure and the use of a common mechanism to maintain both the rDNA and chromosomal termini.
More than half of children with DBA have mutations in a
ribosomal protein gene, and mutations
at least 11 such genes have been linked to DBA.
At low cytostatic concentrations, ActD causes
ribosomal stress, which decreases MDM2 activity, resulting in p53 stabilization and activation.
Further,
at a low cytostatic concentration (2 nM), ActD causes
ribosomal stress leading to a decrease in HDM2 activity and thereby p53 stabilization and activation.