Quantitative single cell monitoring of protein synthesis
at subcellular resolution using fluorescently labeled tRNA.
This technique allows us to capture images of biological processes, for instance to trace individual tumor cells in mice for several weeks
at subcellular resolution.
Not exact matches
«By offering the distinct advantage of
subcellular resolution and avoiding the undesirable influence of fluorescent dyes, we believe our technique can complement FDG in clinical PET imaging for visualizing glucose uptake activity
at the cellular level,» says the lead author Fanghao Hu, a Ph.D. candidate in chemistry.
A high -
resolution map of the human cell has been generated — part of the Human Protein Atlas database — that provides the in situ localization of 12,036 human proteins
at a single - cell level, covering 30
subcellular structures, and enabling 14 major organelle proteomes to be defined.
The combination allows for the study of 3D
subcellular processes in their native multicellular environments
at high spatiotemporal (space and time)
resolution.