Sentences with phrase «at these cancer drugs»

«Our results suggest that we've been looking at these cancer drugs the wrong way — as tumour - targeting drugs — instead of what we now feel is their most important biological role: as immune stimulating therapy.»

Not exact matches

Zymeworks will be putting its two leading drug candidates, both targeted at breast cancer, into clinical trials in the next few months.

The striking example I focused on then was the cancer drug Avastin, developed by Genentech (now Roche)-- which, at the time, had been studied in at least 400 completed human clinical trials for various cancers.

or, more radically, for posting their genetic data to an anonymized, shared research database that might be used to identify those at risk for certain diseases or to identify those who respond better to specific classes of drugs, from beta blockers to cancer medicines.

Analysts at the investment bank said the Dow member's sales could boom because of Keytruda, a blockbuster drug used to treat lung cancer.

As a PhD candidate at Weill Cornell Medical School, Piraye Beim spent much of her time trying to figure out why a particular cancer drug was lifesaving for some patients but useless — or worse — for most.

But a late - stage clinical trial called CheckMate - 026 for the drug failed to meet its primary goal of halting cancer progression in advanced, untreated patients whose tumors consisted of at least 5 % PD - L1.

John Rountree, managing partner at Novasecta, discusses the fallout of a disappointing breast cancer drug trial for pharmaceutical firm Roche.

Researchers at Israel's Technion Institute of Technology are experimenting with a nanoparticle «barcode» system in order to trace the efficacy of cancer drugs.

Gilead CEO John Milligan speaks to CNBC's Meg Tirrell at the J.P. Morgan Health Care Conference about the company's M&A outlook, drug pricing and their work on cancer and Hepatitis C treatments.

In a clinical trial of more than 600 participants, Empliciti, when used with cancer drug Revlimid and steroid dexamethasone was better at delaying when the cancer worsened than just the two drugs alone.

So when a venture capitalist called last fall asking her to lead a small cancer startup, she jumped at the opportunity to focus on a single drug — with no bureaucracy or politics.

Cancer immunotherapies, or treatments that use the body's immune system to fight cancerous cells, were once again the most hotly anticipated drug class at the conference.

But still only a fraction of cancer patients at the advanced state Belvin was at, and given the drug Belvin got, experience the kind of medical «comeback» she did.

Merck — Merck was upgraded to «buy» from «neutral» at Goldman Sachs and added to Goldman's «Conviction Buy» list, based on Merck's success with its cancer drug Keytruda.

But treating cancer becomes less mysterious every day, and today Ignyta is writing a new story, identifying the genomic causes of cancer and creating targeted cancer drugs that attack cancer at its source.

At Epic Sciences, we develop clinical solutions that accelerate drug development and provide valuable insights into the dynamics of cancer growth, evolution and heterogeneity.

Highly compensated employees, like those at Chase or at Amazon headquarters, may be particularly attracted to cutting - edge cancer treatments or the latest prescription drugs, he noted.

UCSD's renowned Cancer Therapeutics Training Program, also known as CT2, addresses the shortage of professionals qualified to oversee the development of innovative, new cancer drugs through its two - year intensive post-doctoral student training at National Cancer Institute - designated Comprehensive Cancer CeCancer Therapeutics Training Program, also known as CT2, addresses the shortage of professionals qualified to oversee the development of innovative, new cancer drugs through its two - year intensive post-doctoral student training at National Cancer Institute - designated Comprehensive Cancer Cecancer drugs through its two - year intensive post-doctoral student training at National Cancer Institute - designated Comprehensive Cancer CeCancer Institute - designated Comprehensive Cancer CeCancer Centers.

Furthermore, Celgene is generating free cash flow at a rate of over $ 1 billion per quarter, giving it plenty of options to acquire new drugs, such as with the deal it announced earlier this month to buy Impact Biomedicines and its potential blockbuster drug for a rare form of blood cancer, and its latest announced buyout of CAR - T developer Juno Therapeutics.

Rick Perry and Michele Bachmann, two presidential candidates who sparred over the issue of Texas vaccinations, may be floundering in the polls, but the topic of Merck's controversial Gardasil is heating up — with an Austrian physician who studied the drug saying it is not only dangerous, but useless in reducing cervical cancer, the stated reason it was administered to young girls at the behest of Gov. Perry.

Looking at sixty - seven recent drug discovery projects based on preclinical cancer biology research, they found that in more than 75 percent of cases the published data did not match up with their in - house attempts to replicate.

These drugs were used primarily to treat cancer but they were also reasonably effective in producing medical abortion, at least up to eight weeks gestation.

The days and weeks of commemoration organized at the secular level by bodies such as the United Nations Organization and its related agencies can help orient the eucharistic communities also to issues such as children's rights, women's emancipation, the aged, foreign debt, peace, environment, food, employment, AIDS, drugs, crime, cancer... etc..

Many laboratory tests were performed and chemotherapy — requiring intravenous punctures — was resumed, even though studies had shown that this type of cancer does not respond significantly, if at all, to drug treatment, and even though complications and side effects from the drugs were expected.

This was before Mackey had won a single Iditarod, let alone four straight; before he used what he calls his marathon style — catnapping as his sled moves and covering 100 - mile chunks at a moderate pace without prolonged rest, instead of sprinting from rest stop to rest stop like most other racers — to win an unprecedented double (the Yukon Quest, the world's other 1,000 - mile dogsled race, and just weeks later the Iditarod) not once but twice; before he became so dominant that slower competitors complained they had no chance to finish within five days of him (the requirement for an official place and a commemorative belt buckle); and before a rival pushed for drug testing at the 2010 Iditarod, suspecting that Mackey's secret was his prescription for medical marijuana to alleviate the side effects of cancer treatment.

Breech Twins and higher order multiples Previous CS Pre-Eclampsia Placenta praevia Cervical incompetence Previous late stillbirth Previous premature birth Grand multiparty Age under 18 Age over 35 Smoking Drug use Severe mental health issue Epilepsy Type 1 diabetes Type 2 diabetes Gestational diabetes Asthma GBS positive Abnormal antibodies Transplant recipient Congenital heart disease Known foetal abnormality Immunosuppressive medication MS Physical disability Intellectual disability Hypothyroidism Hyperthyroidism Previous shoulder dystocia Previous 3rd or 4th degree tear Sickle Cell anaemia BMI under 18 or over 35 at conception Previous massive PPH APH in current pregnancy HIV / AIDS Hepatitis B or C Active TB IUGR Oligohydramnios Polyhydramnios Child previously removed from custody because of abuse Uterine abnormalities such as uterine septum or double uterus Previous uterine surgery for fibroids Chronic renal problems Hypertension Auto immune condition Previous stroke or blod clot Cancer Domestic violence or abusive home Prisoners Homeless women

(borrowed from Dr Kitty) Breech Twins and higher order multiples Previous CS Pre-Eclampsia Placenta praevia Cervical incompetence Previous late stillbirth Previous premature birth Grand multiparty Age under 18 Age over 35 Smoking Drug use Severe mental health issue Epilepsy Type 1 diabetes Type 2 diabetes Gestational diabetes Asthma GBS positive Abnormal antibodies Transplant recipient Congenital heart disease Known foetal abnormality Immunosuppressive medication MS Physical disability Intellectual disability Hypothyroidism Hyperthyroidism Previous shoulder dystocia Previous 3rd or 4th degree tear Sickle Cell anaemia BMI under 18 or over 35 at conception Previous massive PPH APH in current pregnancy HIV / AIDS Hepatitis B or C Active TB IUGR Oligohydramnios Polyhydramnios Child previously removed from custody because of abuse Uterine abnormalities such as uterine septum or double uterus Previous uterine surgery for fibroids Chronic renal problems Hypertension Auto immune condition Previous stroke or blod clot Cancer Domestic violence or abusive home Prisoners Homeless women

At the same time that the millionaire collects his paracetamol, cancer patients are being denied access to modern and potentially life - saving drugs because the NHS can't afford them.

«Identities of Cabinet Ministers» Parliamentary Private Secretaries begin to emerge Main Cameron promises to look at early introduction of Cancer Drugs Fund»

A diagnosis of breast cancer brings a complex range of emotional and practical concerns, and being unable to access necessary drugs can only cause extra anxiety at an already difficult time.

But heavy use of immunosuppressant drugs weakened her and she succumbed to cancer in April at the age of 49, the BBC's Hugh Schofield in Paris...

With new tests to identify women who are at heightened risk of breast cancer, new drugs aimed at preventing allergies, and the discovery of new genes that are key to the progression of conditions like Alzheimer's - to give just three examples - we are at the dawn of a whole new era:

Notes to Editors The report, «How alcohol industry organisations mislead the public about alcohol and cancer», by Mark Petticrew, Nason Maani Hessari, Cécile Knai and Elisabete Weiderpass, will be published online in Drug and Alcohol Review at 22:00 6 September 2017 The Institute of Alcohol Studies is an independent institute bringing together evidence, policy and practice from home and abroad to promote and informed debate on alcohol's impact on society.

As a result, waiting times are higher in Wales, cancer patients are being denied life - prolonging drugs which they would have access to if they lived in England, and spending on medicines has «decreased at a faster rate than elsewhere in the UK», according to the Office for Health Economics.

He has helped found at least two dozen biotech companies, with foci ranging from cancer drug delivery to products for hair and skin.

Professor Josep Tabernero, a member of the scientific committee for the EORTC - NCI - AACR Symposium and head of the medical oncology department at Vall d'Hebron University Hospital and director of the Vall d'Hebron Institute of Oncology, Barcelona, Spain, commented: «These are encouraging results, which show that galeterone has significant clinical activity in men with castration - resistant prostate cancer that fails to respond to other drugs.

«This phase III trial will be noteworthy for being the first prostate cancer trial to assess a biomarker, namely AR - V7 in circulating tumour cells, as a predictor of response at the same time as testing the efficacy of the drug,» Prof Taplin will conclude.

«Our findings provide a rationale to pursue the new use of these «old» antidepressant drugs to benefit late - stage prostate cancer patients with signs and symptoms of metastasis,» said Wu, an assistant professor of pharmacy at WSU Spokane.

She pursued a postdoc at the Moffitt Cancer Center in Tampa, Florida, in cancer drug discCancer Center in Tampa, Florida, in cancer drug disccancer drug discovery.

«Once this novel tumor - homing agent binds to the EphA2 receptor, the oncogene functions as a cancer - specific molecular Trojan horse for paclitaxel, carrying the drug inside the cancel cell, killing the cell, and thwarting metastasis,» said Maurizio Pellecchia, a professor of biomedical sciences at UCR's School of Medicine who led the research.

«Because this binding causes EphA2 internalization, we also sought to conjugate 123B9 with paclitaxel and thus direct the drug to migrating cancer cells,» said Pellecchia, who holds the Daniel Hays Chair in Cancer Research acancer cells,» said Pellecchia, who holds the Daniel Hays Chair in Cancer Research aCancer Research at UCR.

He says that using a liquid biopsy test that was developed and now offered at Dana - Farber Cancer Institute, he was able to determine that the patient did indeed have the mutation, making her a good candidate for drugs that target it.

A research team at the University of California, Riverside has discovered a way for chemotherapy drug paclitaxel to target migrating, or circulating, cancer cells, which are responsible for the development of tumor metastases.

Researchers at Houston Methodist used computer modeling to find an existing investigational drug compound for leukemia patients to treat triple negative breast cancer once it spreads to the brain.

But in patients, the drugs are «a serial failure,» says Vuk Stambolic, a cancer researcher at Princess Margaret Hospital and the Ontario Cancer Institute in Toronto, Ccancer researcher at Princess Margaret Hospital and the Ontario Cancer Institute in Toronto, CCancer Institute in Toronto, Canada.

Such keys could be used to unlock a cancer drug - filled DNA box at a tumour site.

«The fine particles of this drug allow for it to be released slowly and stay in the abdomen,» said Katherine Roby, Ph.D., research associate professor in the Department of Anatomy and Cell Biology at KU Medical Cancer, who started her pre-clinical work on Nanotax more than a decade ago.

Researchers at Southern Methodist University, Dallas, have discovered three new drug - like compounds that could ultimately offer better odds of survival to prostate cancer patients.

Tamara Minko and colleagues at Rutgers University in New Jersey decided to encapsulate the lung cancer drug doxorubicin in fatty bubbles that are small and light enough to be inhaled.