Sentences with phrase «at times cycled»

a course of antibiotics is often prescribed and at times cycled to prevent tolerance.

At the time cycling tours tended to focus on point - to - point excursions.

I understand yr position Steve, but at some time the cycle of «redemptive violence» needs to be challenged if we really want to move toward peace, and isn't that where the words of Jesus will be most effective.

Not exact matches

Many of the trends that the niche ETFs are chasing are actually part of boom - and - bust cycles — meaning they could suffer at the wrong time — shortly after the ETF is created.

At many times during their brand life cycles, they hit a fork in the road and had to evolve to continue their success.

In the near future, we believe that site stakeholders will be able to use this knowledge to react in real time to each individual's needs at each unique stage in the conversion cycle.

(His timing was off, he says, as he got in at the peak of the juice concentrate market cycle — yes, there is such a thing.)

You're on your diurnal cycle, and what alcohol's really good at doing is completely f — king your body clock up — you'll stay up when you're meant to go to sleep, you'll sleep at times when you're supposed to stay up.

Additionally, the layer can heat each side of the bed, measure sleep trends (but for adults, this time) and wake you up at the lightest part of your sleep cycle.

Plus, a sleep sensor attached to your bed analyzes your body movements, breathing, and heart rate to wake you up at the most beneficial time of your sleep cycle.

The entire committee meets 15 times in an admissions cycle, while subsets of the group will gather for other sessions to take a second look at candidates who were initially declined for an interview.

We saw an opportunity to buy an M&A business at the right time, the low end of the cycle.

As of January at the recent high the trailing P / E was at 21 times earnings, which really gets up there, and so I think for the next year or so as we approach and enter late cycle, that's really gonna be the big part of the conversation.

We often work with entrepreneurs who are cycling through the product - development process at the same time they're raising money.

A team of researchers at UCI had been experimenting with nanowires for potential use in batteries, but found that over time the thin, fragile wires would break down and crack after too many charging cycles.

«In a campaign cycle that has been nothing but a race to the bottom — at such a critical moment for our nation — and with so many who have tried to be respectful of a record primary vote, the time has come for Governor Pence to lead the ticket,» Huntsman told the Salt Lake Tribune.

This positive cycle allows them to justify large capital investments in their facilities and provide substantial returns for their shareholders, as share prices for these global companies are at all - time highs.

«It was just deemed too difficult to get through all of the hurdles that they would need to get through, and the level of support they were likely to receive on it was thought to be too low to generate such controversy, particularly at a sensitive (time) in an election cycle,» the source said.

That led to what Piotrowski calls a miserable existence — an endless cycle of unfulfilling contracts that had Capy working on four to five games at a time, spending about four to five months on each.

At the same time, investors are skeptical of oil and commodity investments even though they typically outperform in late - cycle periods.

«We're at a good time in the cycle right now, but I would suggest that you go back and look at the tougher years in 2009 - 2010 and see how much of a struggle it's been for the entire industry during those down cycles.»

These risks and uncertainties include: Gilead's ability to achieve its anticipated full year 2018 financial results; Gilead's ability to sustain growth in revenues for its antiviral and other programs; the risk that private and public payers may be reluctant to provide, or continue to provide, coverage or reimbursement for new products, including Vosevi, Yescarta, Epclusa, Harvoni, Genvoya, Odefsey, Descovy, Biktarvy and Vemlidy ®; austerity measures in European countries that may increase the amount of discount required on Gilead's products; an increase in discounts, chargebacks and rebates due to ongoing contracts and future negotiations with commercial and government payers; a larger than anticipated shift in payer mix to more highly discounted payer segments and geographic regions and decreases in treatment duration; availability of funding for state AIDS Drug Assistance Programs (ADAPs); continued fluctuations in ADAP purchases driven by federal and state grant cycles which may not mirror patient demand and may cause fluctuations in Gilead's earnings; market share and price erosion caused by the introduction of generic versions of Viread and Truvada, an uncertain global macroeconomic environment; and potential amendments to the Affordable Care Act or other government action that could have the effect of lowering prices or reducing the number of insured patients; the possibility of unfavorable results from clinical trials involving investigational compounds; Gilead's ability to initiate clinical trials in its currently anticipated timeframes; the levels of inventory held by wholesalers and retailers which may cause fluctuations in Gilead's earnings; Kite's ability to develop and commercialize cell therapies utilizing the zinc finger nuclease technology platform and realize the benefits of the Sangamo partnership; Gilead's ability to submit new drug applications for new product candidates in the timelines currently anticipated; Gilead's ability to receive regulatory approvals in a timely manner or at all, for new and current products, including Biktarvy; Gilead's ability to successfully commercialize its products, including Biktarvy; the risk that physicians and patients may not see advantages of these products over other therapies and may therefore be reluctant to prescribe the products; Gilead's ability to successfully develop its hematology / oncology and inflammation / respiratory programs; safety and efficacy data from clinical studies may not warrant further development of Gilead's product candidates, including GS - 9620 and Yescarta in combination with Pfizer's utomilumab; Gilead's ability to pay dividends or complete its share repurchase program due to changes in its stock price, corporate or other market conditions; fluctuations in the foreign exchange rate of the U.S. dollar that may cause an unfavorable foreign currency exchange impact on Gilead's future revenues and pre-tax earnings; and other risks identified from time to time in Gilead's reports filed with the U.S. Securities and Exchange Commission (the SEC).

Suddenly, in a cycle that repeats every hour, the blades stop whirring, and a robotic arm swoops down and uses its powerful suction shoe to slowly pick up eight curved six - ton concrete panels one at a time and place them on the newly carved wall in a clockwise pattern.

Another advantage of having a savings account is liquidity, which means funds are accessible at any time, though that access is limited to a maximum of six withdrawals per monthly statement cycle.

At the same time that SARAO ran this lengthy cycle of the dynamic layering technique, he aggressively used the 188 - and -289-lot spoofing technique.

You could make the argument while their was less short - term volatility at the time, the greater long term systemic instability occurred after after the late 90's and 04 - 2006 tightening cycle.

Factors that could cause or contribute to actual results differing from our forward - looking statements include risks relating to: failure of DBRS to rate the Notes at the anticipated ratings levels, which is a closing condition, or at all; changes in the financial markets, including changes in credit markets, interest rates, securitization markets generally and our proposed securitization in particular; the willingness of investors to buy the Notes; adverse developments regarding OnDeck, its business or the online or broader marketplace lending industry generally, any of which could impact what credit ratings, if any, are issued with respect to the Notes; the extended settlement cycle for the scheduled closing on April 17, 2018, which may exacerbate the foregoing risks; and other risks, including those described in our Annual Report on Form 10 - K for the year ended December 31, 2017 and in other documents that we file with the Securities and Exchange Commission from time to time which are or will be available on the Commission's website at www.sec.gov.

The third reason is that not all advanced economies will be exiting from UMP at the same time, because they are at different points in the business cycle.

As is frequently detailed on this blog, stocks and ETFs trading at new 52 - week or all - time highs typically repeat the «base, breakout, base, breakout» cycle several times before eventually entering into a substantial correction, as there is a complete lack of overhead supply (no technical price resistance).

In this environment, credit spreads have a more difficult time getting back to and staying at their lowest points in the cycle despite positive fundamentals.

Moderate interest rates were associated with a whole range of subsequent returns over the following decade, and we know that those outcomes were 90 % correlated with the level of valuations at the beginning of those periods (on reliable measures such as market cap / GDP, price / revenue, Tobin's Q, the margin - adjusted Shiller P / E, and others we've presented over time - see Ockham's Razor and the Market Cycle).

In addition to removing at least $ 450 billion of bonds from its balance sheet this cycle, the Fed has communicated intentions to raise interest rates three times this year and two next year, on the back of five completed rate hikes.

At that time, it also announces new markets to be reviewed for potential market reclassification in the upcoming cycle.

However, as the market has evolved and grown, sellers have begun to use secondary sales as a portfolio management tool or to obtain liquidity at various times in the investment cycle.

At the same time, Canadian exports and business spending are still weaker than you would expect to see at this stage of the business cyclAt the same time, Canadian exports and business spending are still weaker than you would expect to see at this stage of the business cyclat this stage of the business cycle.

It is a way for investors to track the movement of any particular stock at any time to observe the progress of the movement within the stock market trading cycle.

«The world isn't really on an annual cycle anymore,» GE head of human resources Susan Peters said at the time, explaining that millennial workers in particular wanted faster, more frequent, mobile - enabled feedback.

over at Jay Baer's blog The time is ripe to ask with new data available as part of Hubspot's IPO, which confirms they are burning a lot of cash (like everyone else from startup to Amazon) If the Gartner Hype Cycle holds, Inbound and Social Media are overdue for a beating from the press Don't believe the hype, effective inbound campaigns trump everything Inbound is the right message for the mass market, and will continue to be even if the press beats on it.

Fed has hiked 14 times and 10 yr rates are unchanged while 30 yr rates are 60bp lower than at the beginning of the tightening cycle.

As the Gartner Hype Cycle celebrates its 20th year, Gartner said that as enterprises set out on the journey to becoming digital businesses, identifying and employing the right technologies at the right time will be critical.

«By the time 10 - year and 2 - year Treasuries reach parity, as is almost the case now, the economy is typically slowing and the Fed is at or near the end of its tightening cycle.»

Business cycle risk High yield issuers typically have riskier business strategies and more leveraged balance sheets, exposing them to greater risk of default at times of a downturn in business conditions.

The most extreme readings prior to the current cycle occurred at the 1929, 1972 and 1987 peaks, all at 20 times record earnings.

One is that stock prices are indeed three times the level at which they are likely to end the current market cycle.

At the time, it was believed that $ 620 million of the ICO proceeds would go toward development over a four - year cycle.

There's also the fact that, according to reports, the singer has been at work on a new album for some months, and judging by her usual release cycle - a summer single followed by an album in November - it would be just about time for things to begin rolling.

At the same time, we want to protect our ability to provide significant upside to shareholders as the economic cycle turns.

At the same time, we can't ignore the historical implications of past rate hike cycles.

This is the best time to build, at what management believes is the beginning of a new positive gold price cycle.

Unless weekly options are available, standard equity options typically trade four months at a time: the front month (nearest expiration), the next month, and two future «cycle» months.