Sentences with phrase «atherosclerotic cardiovascular disease»

After six months — the equivalent of 20 human years — the mice demonstrated an impairment of arteries that is known to lead to the development of atherosclerotic cardiovascular disease in humans.

The trial included 501 patients with atherosclerotic cardiovascular disease (ASCVD) and elevated LDL cholesterol (> 70mg / ml) despite maximum tolerated statin therapy and patients without ASCVD but with high cardiovascular risk conditions such as diabetes and familial hypercholesterolaemia in whom LDL cholesterol was > 100mg / dl despite maximally tolerated statin therapy.

In March, the Committee for Medicinal Products for Human Use (CHMP) of the European Medicines Agency (EMA) adopted a positive opinion to include a new indication for adults with established atherosclerotic cardiovascular disease (myocardial infarction, stroke or peripheral arterial disease) to reduce cardiovascular risk by lowering LDL - C levels.

He found 10 percent of the African - American patients suffered from atherosclerotic cardiovascular disease — defined as a heart attack, ischemic heart disease, angina, coronary artery disease or atherosclerotic disease of any artery.

When he tallied up patients with connective tissue disease — such as rheumatoid arthritis, lupus, scleroderma or dermatomyositis — there was a clear connection between CTD and increased risk of atherosclerotic cardiovascular disease.

Though cardiovascular disease, which is characterized in part by atherosclerosis, or plaque build - up, is a leading cause of death in the elderly, almost 60 percent of elderly patients with atherosclerotic cardiovascular disease (CVD) exhibit no conventional risk factors, or just one.

Triglyceride - rich lipoproteins and atherosclerotic cardiovascular disease - New insights from epidemiology, genetics, and biology.

American Thyroid Association guidelines recommend considering levothyroxine therapy at thyrotropin levels of 10 mIU / L or less when there are clear symptoms of hypothyroidism, positive thyroid autoantibodies or evidence of atherosclerotic cardiovascular disease (hardening of the arteries) or heart failure.

«Women should be screened for heart disease, including finding out their atherosclerotic cardiovascular disease (ASCVD) score — also called the «A-risk score,» Bairey Merz said.

«These findings raise new questions about the links between inflammation, connective tissue diseases and atherosclerotic cardiovascular disease,» said study author Francis Alenghat, MD, PhD, assistant professor of medicine in the section of cardiology at the University of Chicago.

The association of CTD with atherosclerotic cardiovascular disease «was more prominent in African - Americans and in the young,» he said.

Nonetheless, «the findings show that CTD is associated with higher prevalence of atherosclerotic cardiovascular disease, an association that is accentuated in African - Americans and in young adults,» Alenghat said.

Study investigates whether modern statin guidelines accurately identify African American patients with atherosclerotic cardiovascular disease.

ABI indicates ankle - brachial index; ALT, alanine transaminase; ASCVD, atherosclerotic cardiovascular disease; CAC, coronary artery calcium; CK, creatine kinase; FH, familial hypercholesterolemia; LDL - C, low - density lipoprotein cholesterol; MI, myocardial infarction; RCT, randomized controlled trial; and ULN, upper limit of normal.

ABI indicates ankle - brachial index; ASCVD, atherosclerotic cardiovascular disease; CAC, coronary artery calcium; hs - CRP, high - sensitivity C - reactive protein; LDL - C, low - density lipoprotein cholesterol; MI, myocardial infarction; and RCT, randomized controlled trial.

4 Thompson, P.D., et al. «Exercise and physical activity in the prevention and treatment of atherosclerotic cardiovascular disease a statement... continue Regular exercise such as running increases Brain Derived Neurotrophic Factor (BDNF), which regulates the development and plasticity of the central nervous system, although the benefit may be lower in women compared with men.

It relates to a recently discovered protein PCSK9 and tells a story of how age - related loss of LDL receptors leads to increase in LDL, associated uncontrollable cardiovascular inflammation, and atherosclerotic cardiovascular disease — the main killer -LSB-...]

In many persons, the risks of atherosclerotic cardiovascular disease, diabetes, and obesity are linked to insulin resistance.